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ClinicalTrials.gov public records Last synced Oct 2, 2026, 7:02 AM EDT

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Showing 25–48 of 110 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Neuromuscular Electrical Stimulation (NMES) Clear all
Completed Not applicable Interventional Results available

Impact of Direct Current Electrical Stimulation on Spasticity Levels and Functional Muscle Use in MS

NCT04942938
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Neubie
Device
Lead sponsor
CommonSpirit Health
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Littleton, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 4, 2025 · Synced Oct 2, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional

Quadriceps Strengthening ACL Reconstruction

NCT07015541
View directory record Official record
Conditions
ACL Tear
Interventions
NMES and BFR, Standard physical therapy
Other
Lead sponsor
Stanford University
Other
Eligibility
13 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Sunnyvale, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 2, 2026, 7:02 AM EDT
Completed No phase listed Observational

Infant Modified Constraint Induced Movement Therapy Paired With Neuromuscular Electrical Stimulation: a Case Series

NCT05134272
View directory record Official record
Conditions
Hemiplegia, Cerebral Palsy, Unilateral Cerebral Palsy
Interventions
Neuromuscular electrical stimulation, Modified constraint induced movement therapy, Standard care for infant with asymmetrical hand function
Device · Behavioral
Lead sponsor
Kathy Grinde
Other
Eligibility
7 Months to 10 Months
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Maple Grove, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 27, 2023 · Synced Oct 2, 2026, 7:02 AM EDT
Completed Phase 2Phase 3 Interventional

Adjunctive Neuromuscular Electrical Stimulation for the Rehabilitation of Swallowing

NCT01279824
View directory record Official record
Conditions
Dysphagia
Interventions
swallowing therapy
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 90 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 5, 2012 · Synced Oct 2, 2026, 7:02 AM EDT
Not yet recruiting Not applicable Interventional

Determining the Effects of Ischemic Conditioning and Neuromuscular Electrical Stimulation on Overall Function After Lower Limb Amputation

NCT07664995
View directory record Official record
Conditions
Lower Limb Amputation Above Knee, Below Knee Amputation
Interventions
Blood pressure cuff, Neuromuscular Electrical Stimulation
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 2, 2026, 7:02 AM EDT
Terminated Not applicable Interventional Results available

A 12-Week Home-Based Electrical Stimulation Program for Strength in Adults With Knee Osteoarthritis

NCT05765435
View directory record Official record
Conditions
Osteoarthritis, Osteoarthritis, Knee
Interventions
12-week exercise and walking program, NMES, FES
Other · Device
Lead sponsor
Cionic, Inc.
Industry
Eligibility
22 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Electrical Stimulation to Strengthen Muscles in the Lower Legs in Patients Requiring Prolonged Mechanical Ventilation

NCT01825135
View directory record Official record
Conditions
Muscle Weakness
Interventions
Neuromuscular electrical stimulation, sham stimulation
Device
Lead sponsor
RML Specialty Hospital
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Hinsdale, Illinois
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced Oct 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

Transitional Rehabilitation in CABG Patients

NCT03892460
View directory record Official record
Conditions
Coronary Artery Disease, Coronary Artery Bypass Graft Surgery
Interventions
neuromuscular electrical stimulation
Device
Lead sponsor
University of Vermont
Other
Eligibility
50 Years to 80 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Oct 2, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromuscular Electrical Stimulation: A Novel Treatment for Improving Metabolism

NCT06722391
View directory record Official record
Conditions
Insulin Resistance
Interventions
Neuromuscular Electrical Stimulation (Sensory), Neuromuscular Electrical Stimulation, Resistance Training
Device · Other
Lead sponsor
University of Texas, El Paso
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2031
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Oct 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trigger Point Dry Needling With and Without Electrical Stimulation in Healthy Subjects

NCT07384247
View directory record Official record
Conditions
People With Identified Painful Trigger Points (Tp) Within the Soleus and Gastrocnemius Muscles Complex, Healthy Subjects or Volunteers
Interventions
Dry needling with electrical stimulation, Dry needling, Electrical stimulation, Sham
Procedure
Lead sponsor
University of Rhode Island
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Kingston, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

Alternative Exercise Program to Improve Skeletal Muscle Function and Fatigue in Cancer Survivors

NCT02739620
View directory record Official record
Conditions
Breast Cancer
Interventions
Neuromuscular electrical stimulation
Device
Lead sponsor
University of Vermont
Other
Eligibility
40 Years to 70 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Oct 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Metabolic Health in Individuals With Spinal Cord Injury (SCI)

NCT03204240
View directory record Official record
Conditions
Spinal Cord Injuries, Skeletal Muscle Atrophy, Metabolic Disease
Interventions
Neuromuscular electrical stimulation
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Oct 2, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional

Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty

NCT06953375
View directory record Official record
Conditions
Total Knee Arthroplasty, Functional Recovery, Aging, Physical Therapy
Interventions
NMES, Usual Care
Procedure · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
3,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
3
States / cities
Aurora, Colorado • Murray, Utah
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Training Intrinsic Foot Muscles

NCT03670563
View directory record Official record
Conditions
Muscular Weakness
Interventions
Short foot exercise protocol, Short foot exercise plus NMES
Other
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 30 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 3, 2019 · Synced Oct 2, 2026, 7:02 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Is There an Alternative to Immediate Home Physical Therapy Following Total Knee Arthroplasty

NCT04060251
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
CyMedica e-vive™ System; CY-1000, iGetBetter telemedicine physical therapy
Device · Other
Lead sponsor
Wolfgang Fitz, M.D.
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 7, 2023 · Synced Oct 2, 2026, 7:02 AM EDT
Terminated Not applicable Interventional

Treatment of Muscle Weakness in Critically Ill Patients

NCT02247895
View directory record Official record
Conditions
Critical Illness, Respiratory Failure, Myopathy, Weakness
Interventions
Sham Treatment, Electrical stimulation
Device
Lead sponsor
Gerald Supinski
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 22, 2020 · Synced Oct 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional

The Use of Neuromuscular Electrical Stimulation to Reverse Muscle Atrophy in Patients With Rheumatoid Arthritis

NCT00924625
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Neuromuscular electrical stimulation, Volitional exercises
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2014 · Synced Oct 2, 2026, 7:02 AM EDT
Not listed Phase 1 Interventional

Electrical Stimulation After Total Knee Arthroplasty

NCT00224913
View directory record Official record
Conditions
Total Knee Arthroplasty, Osteoarthritis
Interventions
Neuromuscular electrical stimulation, Voluntary exercise
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
45 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Oct 12, 2005 · Synced Oct 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Home-based NMES Therapy for Knee Osteoarthritis Pain

NCT04128618
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
CyMedica e-vive NMES
Device
Lead sponsor
CyMedica Orthopedics, Inc
Industry
Eligibility
21 Years to 85 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 25, 2020 · Synced Oct 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

Use of Neuromuscular Electrostimulation (NMES) for Treatment or Prevention of ICU-Associated Weakness

NCT00709124
View directory record Official record
Conditions
Intensive Care Unit, Muscle Weakness
Interventions
Neuromuscular Electrostimulation (NMES) CareStim Muscle Stimulation Device (Care Rehab; McLean, VA), Sham
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 23, 2018 · Synced Oct 2, 2026, 7:02 AM EDT
Completed Phase 1 Interventional

Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)

NCT01381354
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Progressive exercise, Neuromuscular electrical stimulation delivered using the electrical therapy device EMPI 300 PV, Modified paleolithic diet, Omega 3 fatty acids, Full Spectrum vitamin, Essential - hydroxytyrosol, Maltodextrin fiber supplement, Mineral boost (magnesium), Niacinamide, Methyl B12, Taurine, creatine, thiamine, riboflavin, N acetylcysteine, alpha lipoic acid, L acetyl carnitine, methyl folate, coenzyme Q, meditation, self massage, learning, Coconut oil
Other · Device · Dietary Supplement + 1 more
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 26, 2018 · Synced Oct 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

Neuromuscular Electrical Stimulation and Mobility in Multiple Sclerosis

NCT02152085
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Narrow pulse, Wide pulse
Device
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 55 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated May 7, 2021 · Synced Oct 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Muscle Stimulation for Physical Function During Stem Cell Transplant

NCT04364256
View directory record Official record
Conditions
Autologous Hematopoietic Stem Cell Transplant
Interventions
RS-4i Plus Sequential Stimulator (RS Medical, Vancouver, WA)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 2, 2026 · Synced Oct 2, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional

Interventions to Enhance Quadriceps Output After ACLR

NCT07674784
View directory record Official record
Conditions
ACL
Interventions
NMES, Vibration
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 2, 2026, 7:02 AM EDT