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ClinicalTrials.gov public records Last synced Sep 3, 2026, 5:31 AM EDT

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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: New ventilator Clear all
Recruiting No phase listed Observational

Exhaled Breath: A Novel Technique for Rapid Diagnosis of Respiratory Diseases and Infections

NCT06775106
View directory record Official record
Conditions
Pulmonary Disease, Critical Illness
Interventions
There is no intervention in this observational study
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 120 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 3, 2026, 5:31 AM EDT
Withdrawn Not applicable Interventional

Paradoxical Response to Chest Wall Loading in Mechanically Ventilated Patients

NCT06093958
View directory record Official record
Conditions
ARDS, COVID-19, Mechanical Ventilation Pressure High, Ventilator-Induced Lung Injury
Interventions
Manual loading of the chest wall
Diagnostic Test
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 6, 2024 · Synced Sep 3, 2026, 5:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

VentFree: A Novel Abdominal Stimulator to Assist With Ventilator Weaning

NCT02224352
View directory record Official record
Conditions
COPD, Weaning Failure
Interventions
Functional neuromuscular electrical stimulation
Device
Lead sponsor
Edward Hines Jr. VA Hospital
Federal
Eligibility
18 Years to 90 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
2
States / cities
Hines, Illinois • Hinsdale, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced Sep 3, 2026, 5:31 AM EDT
Active, not recruiting Not applicable Interventional

A Communication Tool to Improve Communication in the ICU

NCT05780918
View directory record Official record
Conditions
Serious Injury, Communication
Interventions
Best Case/Worst Case-ICU Communication Tool
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
7,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
8
States / cities
Birmingham, Alabama • Davis, California • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 3, 2026, 5:31 AM EDT
Completed Not applicable Interventional Results available

Real-time Effort Driven VENTilator Management

NCT03266016
View directory record Official record
Conditions
Ventilation Therapy; Complications, Diaphragm Disease, Pediatric Respiratory Diseases
Interventions
Computerized Ventilator Protocol, Esophageal Manometry, Respiratory Inductance Plethysmography (RIP), Diaphragm Ultrasound, Maximal Inspiratory Pressure
Other · Diagnostic Test
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
30 Days to 18 Years
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 3, 2026, 5:31 AM EDT
Completed No phase listed Observational

CTTI Risk Factors for HABP/VABP Study

NCT02689531
View directory record Official record
Conditions
Pneumonia, Ventilator-Associated, Pneumonia, Bacterial, Pneumonia, Hospital-Acquired
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
7,530 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
15
States / cities
Birmingham, Alabama • Los Angeles, California • Chicago, Illinois + 12 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2023 · Synced Sep 3, 2026, 5:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessment of Novel Respiratory Protective Devices in Healthcare

NCT02082158
View directory record Official record
Conditions
Comfort, Tolerability
Interventions
Study Procedures
Other
Lead sponsor
National Center for Occupational Health and Infection Control
Federal
Eligibility
18 Years to 90 Years
Enrollment
382 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 22, 2016 · Synced Sep 3, 2026, 5:31 AM EDT
Completed Not applicable Interventional Results available

Physiological Changes With High-Flow Nasal Cannula

NCT03700606
View directory record Official record
Conditions
Respiratory Distress Syndrome in Premature Infant
Interventions
High flow nasal cannula, Nasal CPAP
Procedure
Lead sponsor
Sharp HealthCare
Other
Eligibility
23 Weeks to 28 Weeks
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 3, 2026, 5:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessment of N-95 Facemask for Use in COVID-19 Pandemic in Case of Shortage of Personal Protective Equipment

NCT04416919
View directory record Official record
Conditions
Coronavirus Infection, Disease Prevention
Interventions
Assembled mask
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced Sep 3, 2026, 5:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Transparent Elastomeric Respirator for Aerosol-based Protection

NCT04511390
View directory record Official record
Conditions
Personal Protective Equipment
Interventions
Transparent, reusable respirator
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
3
States / cities
Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Sep 3, 2026, 5:31 AM EDT
Not listed Not applicable Interventional

Proportional Open Ventilation (POV) Device and Its Efficacy in Managing Acute Respiratory Failure in COVID-19 Patients

NCT04581161
View directory record Official record
Conditions
Acute Respiratory Failure, Covid19
Interventions
Life2000® Ventilator
Device
Lead sponsor
Hill-Rom
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Sep 3, 2026, 5:31 AM EDT
Completed Not applicable Interventional Results available

Comparison Between Two Methods of Spontaneous Breathing Trial (SBT)

NCT00400881
View directory record Official record
Conditions
Respiratory Failure
Interventions
automatic tube compensation
Other
Lead sponsor
Texas Tech University Health Sciences Center, El Paso
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Sep 3, 2026, 5:31 AM EDT
Recruiting Not applicable Interventional

ADHERE-LPV Advancing Delivery of High-Quality Evidence-Based Respiratory Efforts in Lung-Protective Ventilation

NCT06895148
View directory record Official record
Conditions
Ventilation
Interventions
New ventilator, control ventilator
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
1,125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 3, 2026, 5:31 AM EDT
Not listed Not applicable Interventional

Novel Lung Trial: Normothermic Ex Vivo Lung Perfusion (Evlp) As An Assessment Of Extended/Marginal Donor Lungs

NCT01365429
View directory record Official record
Conditions
Lung Transplant
Interventions
XPS™ with Steen Solution™
Device
Lead sponsor
XVIVO Perfusion
Industry
Eligibility
18 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
18
States / cities
Los Angeles, California • Aurora, Colorado • Gainesville, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Mar 6, 2018 · Synced Sep 3, 2026, 5:31 AM EDT
Completed Not applicable Interventional Results available

Efficacy Study on Silver-coated ETT Cleaned With a Novel Device

NCT02120001
View directory record Official record
Conditions
Ventilator Associated Pneumonia, Critically Ill
Interventions
ETT cleaning maneuver
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2017 · Synced Sep 3, 2026, 5:31 AM EDT
Terminated Not applicable Interventional

Variable Ventilation During Acute Respiratory Failure

NCT01083277
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
variable ventilation, Conventional ventilation
Device · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2017 · Synced Sep 3, 2026, 5:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

New Reusable Mask Design With Superior Filtration and Fit

NCT04826809
View directory record Official record
Conditions
Covid19, Tuberculosis, Respiratory Viral Infection
Interventions
N95 mask, Nordell single E-100 layer mask, Nordell double E-100 layer mask
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Mankato, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 6, 2023 · Synced Sep 3, 2026, 5:31 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Project 4A: Inspiratory Muscle Training and Diaphragm Strength

NCT02367170
View directory record Official record
Conditions
Sepsis
Interventions
Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure, Midazolam, Volitional Measurement of Maximal Inspiratory Pressure (MIP), Inspiratory Muscle Strength Training (IMST), SHAM Inspiratory Muscle Strength Training (IMST), Diaphragm thickness measurement, Blood and Urine samples
Procedure · Drug · Device + 1 more
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 6, 2018 · Synced Sep 3, 2026, 5:31 AM EDT
Completed Not applicable Interventional Results available

Efficacy Study of a Novel Device to Clean the Endotracheal Tube

NCT01765530
View directory record Official record
Conditions
Endotracheal Extubation, Airway Obstruction, Airway Control, Pneumonia, Ventilator-Associated, Breathing Mechanics
Interventions
ETT cleaning maneuver
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 99 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 17, 2017 · Synced Sep 3, 2026, 5:31 AM EDT