- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Collagen Disorders and/or Avascular Necrosis of the Femoral Condyle, Post-traumatic Loss of Joint Configuration, Moderate Valgus, Varus, or Flexion Deformities
- Interventions
- NexGen TM Monoblock Tibia, NexGen TM Modular Tibia
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 7
- States / cities
- Torrance, California • Wheat Ridge, Colorado • Mooresville, Indiana + 4 more
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–10
of 10
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Osteoarthritis
- Interventions
- Total Knee Replacement
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 842 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2018
- U.S. locations
- 11
- States / cities
- Orange, California • San Diego, California • Fort Collins, Colorado + 8 more
- Conditions
- Knee Osteoarthritis
- Interventions
- Zimmer, Stryker
- Device
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities, Rheumatoid Arthritis
- Interventions
- PERSONA Total Knee, Vanguard Total Knee, NexGen Total Knee
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 181 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 5
- States / cities
- Vail, Colorado • Westminster, Colorado • Springfield, Illinois + 2 more
- Conditions
- Total Knee Arthroplasty, Osteoarthritis
- Interventions
- NexGen CR-Flex Fixed Bearing Knee, NexGen CR Knee
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 189 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2010
- U.S. locations
- 8
- States / cities
- Milford, Delaware • Chicago, Illinois • Rockford, Illinois + 5 more
- Conditions
- Knee Prosthesis
- Interventions
- Stryker posterior cruciat retaining (PCR) total knee arthroplasty (TKA), Zimmer PCR TKA
- Device
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 40 Years to 70 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 4
- States / cities
- Knoxville, Tennessee
- Conditions
- Osteoarthritis, Traumatic Arthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus, Valgus, Flexion Deformities
- Interventions
- NexGen LPS-Flex Mobile Bearing Knee
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- Not listed
- Enrollment
- 266 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2021
- U.S. locations
- 3
- States / cities
- Tamarac, Florida • Auburn Hills, Michigan • Knoxville, Tennessee
- Conditions
- Revision Arthroplasty, Knee
- Interventions
- Condylar Constrained knee system. ( NexGen Legacy Condylar Constrained Knee by Zimmer Biomet), Rotating Hinge Knee ( NexGen Rotating Hinge Knee by Zimmer Biomet)
- Device
- Lead sponsor
- Medstar Health Research Institute
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 186 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2037
- U.S. locations
- 2
- States / cities
- Washington D.C., District of Columbia • Olney, Maryland
- Conditions
- Total Knee Arthroplasty
- Interventions
- The Zimmer NexGen Legacy Knee System, modular cemented tibia, The Zimmer NexGen Legacy Knee System, non-modular cemented tibia., The Zimmer NexGen Legacy Knee System, non-modular uncemented tibia
- Device
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 20 Years to 85 Years
- Enrollment
- 397 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2007
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Total Knee Arthroplasty, Osteoarthritis
- Interventions
- NexGen LPS-Flex Fixed Bearing Knee, NexGen Legacy Posterior Stabilized Knee
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 331 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2010
- U.S. locations
- 14
- States / cities
- Birmingham, Alabama • Decatur, Georgia • Springfield, Illinois + 11 more