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ClinicalTrials.gov public records Last synced Oct 13, 2026, 8:26 PM EDT

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Showing 337–360 of 423 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Nicotine Replacement Therapies Clear all
Completed Phase 4 Interventional Results available

Testing Integrative Smoking Cessation for HIV Patients

NCT05030766
View directory record Official record
Conditions
Smoking, Smoking Cessation, HIV Infections
Interventions
Nicotine Replacement Therapy, Mindfulness Training Smoking Cessation Intervention, Contingency Management Smoking Cessation Intervention
Drug · Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 13, 2026, 8:26 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Social Media Support Groups for Adolescent Vaping Cessation

NCT07540780
View directory record Official record
Conditions
Vaping, Vaping Cessation, Nicotine Dependence
Interventions
Social Media Intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Smoking Cessation in Hispanic Construction Workers

NCT02873377
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicorette Gum, Nicoderm CQ, Smoking Quitline Referral, Behavioral Smoking Cessation Counseling
Drug · Other · Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older · Male only
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Nov 7, 2019 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Phase 4 Interventional Results available

A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV

NCT04490057
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Nicotine patch, nicotine gum, nicotine nasal spray, nicotine inhaler, Varenicline or bupropion, Contingency Management
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
4
States / cities
Bridgeport, Connecticut • New Haven, Connecticut • Brooklyn, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Not applicable Interventional Results available

Contingency Management for Smoking in Substance Abusers

NCT00807742
View directory record Official record
Conditions
Substance Abuse
Interventions
Nicotine Replacement Treatment (NRT), Brief Advice, Contingency Management, Non-Contingent Reinforcement
Drug · Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 23, 2019 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Phase 3 Interventional Results available

Telephone Counseling and the Distribution of Nicotine Patches to Smokers

NCT00851357
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine Patch, Telephone Counseling, Placebo, Self-Help Materials
Drug · Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
4,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 13, 2026, 8:26 PM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Effects of Nicotine Replacement Therapy and D-cycloserine on Nicotine Treatment Seekers

NCT01907594
View directory record Official record
Conditions
Cigarette Smoking
Interventions
D-cycloserine, Nicotine Replacement Therapy (patch), Smoking Cue Exposure, Progressive Muscle Relaxation, Placebo
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 55 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Smoking Treatment in HIV Clinical Care Settings

NCT00297453
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Internet-based smoking treatment, Individual Counseling, self-help
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2012 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Tailored Tobacco Quitline for Rural Veterans

NCT01592695
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Nicotine replacement therapy - transdermal nicotine patch, Tailored behavioral intervention, Tobacco quit line referral, Nicotine replacement therapy - nicotine gum, Nicotine replacement therapy - nicotine lozenge, Bupropion Sustained Release, Varenicline, Combination pharmacotherapy - transdermal nicotine patch + nicotine gum, Combination pharmacotherapy - transdermal nicotine patch + nicotine lozenge, Combination pharmacotherapy - transdermal nicotine patch + bupropion, Alcohol use risk reduction, Behavioral activation for the treatment of depression, Behavioral management of post-cessation weight gain
Drug · Behavioral
Lead sponsor
Iowa City Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 99 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 2, 2019 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Phase 4 Interventional Results available

Combination Nicotine Replacement for Alcoholic Smokers

NCT00064844
View directory record Official record
Conditions
Smoking, Alcoholism
Interventions
Cognitive Behavior Therapy for alcohol and smoking cessation, Nicoderm CQ nicotine patch, Placebo gum, Nicotine gum - Nicorette®
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Newington, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 13, 2021 · Synced Oct 13, 2026, 8:26 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Smoking Cessation for Depressed Smokers

NCT00494728
View directory record Official record
Conditions
Smoking, Depression
Interventions
Smoking Cessation Treatment, Nicotine Replacement Therapy, CBASP
Behavioral · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
16 Years and older
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Not applicable Interventional

Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings

NCT05030272
View directory record Official record
Conditions
Tobacco Use Disorder, Mental Illness, Recurring Major Depressive Disorder, Bipolar Disorder, Schizophrenia, Schizoaffective Disorder, Persistent Depressive Disorder
Interventions
Quit on the Go App (formerly "Learn to Quit " App), Brief advice, Nicotine patch, Smartphone coaching, Nicotine gum, Nicotine Lozenges
Device · Behavioral · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Buffalo, New York • Durham, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Not applicable Interventional

Clinical Effort Against Smoke Exposure in Cystic Fibrosis

NCT04777344
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Tobacco Treatment Specialist (TTS) intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Determinants of Smoking Cessation Among Latinos

NCT01008748
View directory record Official record
Conditions
Smoking Cessation
Interventions
Nicotine Replacement Therapy (NRT), Questionnaire, Counseling, Self-Help Materials
Drug · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 19, 2020 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Not applicable Interventional

Electronic Cigarettes as a Harm Reduction Strategy Among People Living With HIV/AIDS

NCT04218708
View directory record Official record
Conditions
Nicotine Addiction
Interventions
Nicotine patch and gum, Minnesota Nicotine Withdrawal Scale (MNWS), ASSIST (the Alcohol, Smoking and Substance Involvement Screening), Counseling, NIDA Standardized Research E-cigarettes (SREC)
Other · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 20, 2024 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Jail-Based Use of Smoking Cessation Treatment Study

NCT03799315
View directory record Official record
Conditions
Tobacco Use
Interventions
Nicotine Replacement Therapy, Counseling
Drug · Behavioral
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years to 64 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 14, 2020 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adolescent Inpatient Tobacco and ENDS Intervention

NCT05936099
View directory record Official record
Conditions
Vaping, Smoking
Interventions
E-cigarette & Tobacco Use Treatment Intervention
Behavioral
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
14 Years to 21 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Not applicable Interventional Results available

Quit For Life (QFL): Smoking Cessation Among Chinese Smokers Living With HIV

NCT05020899
View directory record Official record
Conditions
Smoking Cessation, HIV Infections
Interventions
Sessions with a trained counselor, Cell phone messages, Offered nicotine replacement therapy, Self-help guide for quitting smoking
Behavioral · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Oct 13, 2026, 8:26 PM EDT
Terminated Phase 3 Interventional Results available

Study to Determine if a New Nicotine Replacement Therapy Can Safely Help Smokers to Quit Smoking

NCT01296698
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Placebo, Nicotine
Drug
Lead sponsor
McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.
Industry
Eligibility
18 Years and older
Enrollment
257 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
19
States / cities
Muscle Shoals, Alabama • Oceanside, California • Griffin, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2012 · Synced Oct 13, 2026, 8:26 PM EDT
Active, not recruiting Not applicable Interventional

Nicotine Replacement Therapy Prescribing and Lung Cancer Screening in Hospitalized Patients

NCT07164404
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
EHR alert
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Not applicable Interventional

Web-Delivered Acceptance & Commitment Therapy for Smokers With Bipolar Disorder

NCT02750904
View directory record Official record
Conditions
Smoking, Bipolar Disorder
Interventions
Experimental plus Nicotine Replacement Therapy, Control plus Nicotine Replacement Therapy
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
4
States / cities
Palo Alto, California • Denver, Colorado • Bedford, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2019 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Pilot Text Messaging Intervention to Reduce Smoking in Office-based Buprenorphine and Inpatient Detoxification Patients

NCT02665208
View directory record Official record
Conditions
Smoking Cessation
Interventions
Treatment As Usual (TAU), Nicotine Replacement Therapies, Text Message Intervention (TMI)
Other · Drug · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Phase 4 Interventional Results available

Integrating Financial Management Counseling and Smoking Cessation Counseling to Reduce Health and Economic Disparities in Low-Income Immigrants

NCT03187730
View directory record Official record
Conditions
Smoking Cessation
Interventions
Integrated Smoking Cessation and Financial Counseling, Waitlist Integrated Smoking Cessation and Financial Counseling, Nicotine Replacement Therapy (NRT)
Behavioral · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 18, 2021 · Synced Oct 13, 2026, 8:26 PM EDT
Completed Not applicable Interventional Results available

Tech and Telephone Smoking Cessation Treatment for Young Veterans With PTSD

NCT03552978
View directory record Official record
Conditions
Smoking Cessation
Interventions
Tech-Facilitated IC Intervention, VA Quitline
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 45 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Oct 13, 2026, 8:26 PM EDT