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ClinicalTrials.gov public records Last synced Oct 29, 2026, 2:48 PM EDT

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Showing 73–96 of 162 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Nicotine cessation program Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Research and Innovation to Stop E-cigarette/Vaping in Young Adults

NCT04974580
View directory record Official record
Conditions
Nicotine Dependence, E-Cig Use
Interventions
Nicotine patch, Phone Counseling, Digital Coaching
Drug · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 24 Years
Enrollment
508 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Phase 4 Interventional Results available

Engagement With an Adaptive Mobile Health Smoking Cessation Intervention

NCT04020718
View directory record Official record
Conditions
Tobacco Use Cessation
Interventions
Brief telephone advice plus tailored text messages, Mailed nicotine replacement therapy, Proactive telephone coaching
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Oct 29, 2026, 2:48 PM EDT
Suspended Not applicable Interventional

SmokefreeSGM Español Pilot, Beta Testing a Text-based Smoking Cessation Intervention for Sexual and Gender Minority(SGM) Groups Preferring Spanish Language

NCT06487806
View directory record Official record
Conditions
Smoking Cessation
Interventions
SmokefreeSGM
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Not applicable Interventional

Women Engaging in Quitting Smoking Together (WE QUIT)

NCT02051803
View directory record Official record
Conditions
Smoking Cessation
Interventions
Distress Tolerance Treatment for Weight Concern (DT-W), Health Education (HE)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 31, 2015 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

End Nicotine Dependence Clinic

NCT03290430
View directory record Official record
Conditions
Smoking Cessation
Interventions
Group Counseling, Individual Counseling, Phone Counseling, Video Counseling, Texting support, Nicotine Replacement Therapy
Behavioral · Drug
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 14, 2020 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Effectiveness of Pharmacists in Implementing the SCRIPT Protocol

NCT02433860
View directory record Official record
Conditions
Pregnancy
Interventions
pharmacist nicotine cessation counseling using SCRIPT protocol
Behavioral
Lead sponsor
Providence Medical Research Center
Other
Eligibility
18 Years and older · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Sep 25, 2017 · Synced Oct 29, 2026, 2:48 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Digitally Enhanced Smoking Cessation for High Risk Smokers

NCT04691297
View directory record Official record
Conditions
Smoking, Smoking Cessation, Lung Cancer Screening, Smoking, Tobacco, Smoking Behaviors
Interventions
Escape, Standard Care
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
55 Years to 77 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tobacco Treatment for Employable Californians, Total IMPACT Study

NCT02478697
View directory record Official record
Conditions
Tobacco Dependence
Interventions
ProChange ExpertSystem
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
3
States / cities
Menlo Park, California • San Francisco, California • San Rafael, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Not applicable Interventional Results available

Comparative Effectiveness of Post-Discharge Strategies for Hospitalized Smokers

NCT01714323
View directory record Official record
Conditions
Cigarette Smoking, Tobacco Smoking, Tobacco Use Disorder
Interventions
Sustained Care, Standard Care
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
1,359 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Boston, Massachusetts • Salem, Massachusetts • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 8, 2018 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Safety and Effectiveness of Sustained Release Bupropion in Treating Individuals With Schizophrenia Who Smoke

NCT00307203
View directory record Official record
Conditions
Tobacco-Use Disorder, Schizophrenia, Psychotic Disorders
Interventions
bupropion SR, Cognitive Behavioral Group Therapy, nicotine replacement therapy
Drug · Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2004
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Financial Incentives to Reduce Pediatric Tobacco Smoke Exposures

NCT03099811
View directory record Official record
Conditions
Asthma, Incentives, Tobacco Smoking
Interventions
Incentive plan, Smoking cessation
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
2 Years to 12 Years
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Phase 1 Interventional

Smoking Termination / Anxiety Reduction Treatment (ST/ART)

NCT01789125
View directory record Official record
Conditions
Smoking, Anxiety Disorders
Interventions
Nicotine Patch, Smoking Termination and Anxiety Reduction Treatment, Education-Supportive Psychotherapy
Drug · Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 23, 2019 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Cancer Disparities Among Latinos in Texas

NCT01504919
View directory record Official record
Conditions
Psychosocial Problem
Interventions
Health Education, Questionnaires, Telephone Counseling Sessions, Nicotine Patches
Behavioral · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
301 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2022
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 31, 2022 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Message Priming and Enrollment in, and Response to, a Smoking Cessation Program: A Pilot Study

NCT00596882
View directory record Official record
Conditions
Smoking Cessation
Interventions
Message Prime
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 2, 2009 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Not applicable Interventional Results available

Preventing Weight Gain and Controlling Blood Pressure During Smoking Cessation in Hypertensive Smokers

NCT00113074
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Hypertension
Interventions
Nicotine Replacement Therapy, Diet
Drug · Behavioral
Lead sponsor
Mark Vander Weg
Other
Eligibility
Not listed
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
2
States / cities
Iowa City, Iowa • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Development of a mHealth Intervention for Ambivalent Smokers

NCT04560868
View directory record Official record
Conditions
Tobacco Use Disorder, Smoking Cessation, Motivation, Behavior, Smoking
Interventions
Control mHealth program, Experimental mHealth program, Nicotine patch
Device · Drug
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 23, 2023 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Early Phase 1 Interventional Results available

Pilot Study on Mindfulness for Tobacco and Alcohol in University Students

NCT01679236
View directory record Official record
Conditions
Nicotine Dependence, Alcohol Use
Interventions
Mindfulness Training for Smokers, Interactive Learning for Smokers
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 29 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 24, 2014 · Synced Oct 29, 2026, 2:48 PM EDT
Recruiting Not applicable Interventional

Pain and Smoking Study 2.0: A Randomized Clinical Trial of Smoking Cessation Among Veterans With Chronic Pain

NCT06442514
View directory record Official record
Conditions
Smoking, Pain, Smoking Cessation
Interventions
PASS2, Treatment as Usual
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 29, 2026, 2:48 PM EDT
Completed No phase listed Observational Results available

Evaluation of a Smoking Cessation Program for Long-Term Abstinence

NCT06746025
View directory record Official record
Conditions
Nicotine Addiction, Smoking Cessation
Interventions
Quit Center cessation program
Behavioral
Lead sponsor
Quit Center LLC
Industry
Eligibility
18 Years and older
Enrollment
371 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Naples, Florida
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Not applicable Interventional Results available

WeChat Quit Coach Pilot Study

NCT05130788
View directory record Official record
Conditions
Smoking Cessation
Interventions
WeChat Quit Coach, Leaflet, Optional Nicotine Replacement Therapy (NRT) Patches or Lozenges
Behavioral · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Smoking, Stress, and Mobile Technology

NCT04838236
View directory record Official record
Conditions
Smoking, Tobacco
Interventions
MASP app + NRT, QuitGuide app + NRT
Other
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
227 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Oklahoma City, Oklahoma • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 29, 2026, 2:48 PM EDT
Recruiting Phase 4 Interventional

Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking Cessation Package for Smokers in HIV Clinical Care

NCT06598397
View directory record Official record
Conditions
Human Immunodeficiency Virus (HIV), Smoking Cessation
Interventions
Motivational Interviewing (MI) Counseling, Peer Mentoring, Skills-based Text Messaging, Combination NRT
Behavioral · Drug
Lead sponsor
New York University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Impact of Alternative Nicotine-Delivery Products on Combustible Cigarette Use

NCT04084210
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Juul Electronic cigarette, Very Low Nicotine Cigarettes, Active Nicotine Patch, Placebo Patch
Device · Other · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years and older
Enrollment
209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
Madison, Wisconsin • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 25, 2023 · Synced Oct 29, 2026, 2:48 PM EDT
Completed Not applicable Interventional

Study on Sit to Quit Phone Intervention

NCT02840435
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Sit to Quit, Quit for Life
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 13, 2019 · Synced Oct 29, 2026, 2:48 PM EDT