- Conditions
- Nicotine Dependence
- Interventions
- Intravenous Nicotine, Progesterone
- Drug
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 18 Years to 40 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2015
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
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Showing 25–42
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- Conditions
- Nicotine Dependence
- Interventions
- Intravenous Nicotine
- Drug
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 18 Years to 40 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2015
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Nicotine Dependence
- Interventions
- Intravenous Nicotine, Progesterone
- Drug
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 18 Years to 40 Years · Female only
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2015
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Nicotine Dependence
- Interventions
- Suvorexant 20 mg, Suvorexant 10 mg, Placebo oral tablet
- Drug
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Nicotine Dependence
- Interventions
- Nicotine, Progesterone
- Other
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 18 Years to 40 Years · Female only
- Enrollment
- 45 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2016
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts
- Conditions
- Smoking
- Interventions
- Nicotine gum - 2 mg and 4 mg, Nicotine lozenges - 2 mg and 4 mg, Nicotine inhaler (4 mg yield) - low and high "dosage" by frequency of puffing, Computer learning
- Drug · Other
- Lead sponsor
- US Department of Veterans Affairs
- Federal
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2009
- U.S. locations
- 1
- States / cities
- West Los Angeles, California
- Conditions
- Tobacco Use Disorder
- Interventions
- Nicotine patch
- Drug
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2005
- U.S. locations
- 2
- States / cities
- Piscataway, New Jersey
- Conditions
- Coronary Artery Disease
- Interventions
- Medical/Behavioral therapy, Standard of Care, Registry
- Other
- Lead sponsor
- Emory University
- Other
- Eligibility
- 21 Years to 90 Years
- Enrollment
- 276 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2028
- U.S. locations
- 5
- States / cities
- Atlanta, Georgia
- Conditions
- Cigarette Smoker, Tobacco Use Disorder
- Interventions
- Nicotine Lozenge, Nicotine Patch, Placebo, Tobacco Cessation Counseling, Varenicline
- Drug · Other
- Lead sponsor
- M.D. Anderson Cancer Center
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 631 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2026
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- THC, Cannabis, Cannabis Use, Cannabis Smoking, Tobacco Use, Vaping
- Interventions
- Cannabis, Nicotine, Pax Loose Leaf Vaporizer, Placebo Marijuana
- Drug · Device · Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Nicotine Dependence
- Interventions
- Cognitive Behavioural Therapy, Contingency Management, Nicotine Transdermal Patch
- Behavioral · Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 14 Years to 19 Years
- Enrollment
- 154 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2015
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Tobacco Use Cessation
- Interventions
- Nicotine lozenge, Nicotine gum, Nicotine patch, Maryland Quitline, John Hopkins Tobacco Treatment Clinic
- Drug · Other
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Tobacco Use Disorder
- Interventions
- ModafinilNicotine Replacement Therapy, Modafinil
- Drug
- Lead sponsor
- Catherine Martin, MD
- Other
- Eligibility
- 16 Years to 40 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003 – 2011
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Dual Use of Cigarettes and E-cigarettes
- Interventions
- Text- and web-based support, Nicotine Replacement Therapy (NRT, nicotine patch), Nicotine replacement therapy lozenge
- Behavioral · Drug
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 321 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2031
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Cigarette Smoking-Related Carcinoma
- Interventions
- Cigarette Smoking, Nicotine Oral Pouch, Questionnaire Administration
- Behavioral · Drug · Other
- Lead sponsor
- Ohio State University Comprehensive Cancer Center
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 55 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Cannabis Use, Tobacco Use, Electronic Cigarette Use
- Interventions
- THC High Dose, THC Low Dose, THC 0mg, E-Cigarette Full Nicotine, E-Cigarette Placebo Nicotine
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Tobacco Use Cessation
- Interventions
- Varenicline, Nicotine Patch, Placebo Patch, Placebo Tablet, Questionnaires, Counseling Sessions, Lab Session, Saliva Test
- Drug · Behavioral · Other
- Lead sponsor
- M.D. Anderson Cancer Center
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 204 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2028
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Nicotine Dependence
- Interventions
- Nicotine
- Other
- Lead sponsor
- Mclean Hospital
- Other
- Eligibility
- 18 Years to 40 Years · Female only
- Enrollment
- 72 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2016
- U.S. locations
- 1
- States / cities
- Belmont, Massachusetts