- Conditions
- Cognitive Impairment Associated With Schizophrenia
- Interventions
- Nicotine patch, MK-4334, Placebo patch, Placebo capsule
- Drug
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 38 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022
- U.S. locations
- 2
- States / cities
- Long Beach, California • Marlton, New Jersey
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Showing 1–9
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- Conditions
- Tobacco Use Disorder
- Interventions
- ModafinilNicotine Replacement Therapy, Modafinil
- Drug
- Lead sponsor
- Catherine Martin, MD
- Other
- Eligibility
- 16 Years to 40 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003 – 2011
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Cigarette Smoking
- Interventions
- D-cycloserine, Nicotine Replacement Therapy (patch), Smoking Cue Exposure, Progressive Muscle Relaxation, Placebo
- Drug · Behavioral
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 21 Years to 55 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Nicotine Dependence, Smoking Cessation
- Interventions
- EVP-6124, Placebo Capsule, NicoDerm Patch (Active), NRT Patch (Placebo), Brief Supportive and Behavioral Treatment
- Drug · Behavioral
- Lead sponsor
- A. Eden Evins
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 345 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2015
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Smoking Cessation
- Interventions
- Meclizine, Nicotine Patch, Placebo
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 146 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 4
- States / cities
- Charlotte, North Carolina • Durham, North Carolina • Raleigh, North Carolina + 1 more
- Conditions
- Cigarette Smoking
- Interventions
- Nicotine Patch, Varenicline, Placebo Nicotine Patch, Placebo Capsule
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 125 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Basic Science Study of the Mechanisms of Attentional Enhancement by Compounds Acting on the Nicotinic Receptor
- Interventions
- Placebo patch & placebo capsule, Placebo patch & galantamine capsule, Nicotine patch & placebo capsule, Nicotine patch and galantamine capsule
- Drug
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 21 Years to 55 Years
- Enrollment
- 43 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Catonsville, Maryland
- Conditions
- Magnetic Resonance Imaging, Cognition, Nicotine, Mecamylamine
- Interventions
- Placebo, Nicotine, Mecamylamine
- Drug
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 21 Years to 50 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2013
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland
- Conditions
- Tobacco Use Disorder, Nicotine Dependence, Cigarette Smoking
- Interventions
- Propranolol, Nicotine Patch, Placebo Propranolol, Placebo Patch
- Drug
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 21 Years to 60 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Tulsa, Oklahoma