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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:41 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 313–336 of 429 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Nicotine replacement Clear all

Conditions: Nicotine Dependence
Interventions: Internet-based smoking treatment, Individual Counseling, self-help; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 207 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Smoking Cessation
Interventions: Tech-Facilitated IC Intervention, VA Quitline; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 45 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Smoking, HIV Infections
Interventions: Varenicline tartrate, Nicotine Replacement Therapy, Biological Control, Motivational Interview; Drug · Other · Behavioral
Lead sponsor: Philip Diaz; Other
Eligibility: 18 Years and older
Enrollment: 294 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Smoking
Interventions: Nicotine Replacement Therapy, Questionnaire; Drug · Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 220 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Pulmonary Complications, HIV Infections
Interventions: Smoking Cessation; Other
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Cigarette Smoking
Interventions: Mindfulness-Based Addiction Treatment, Nicotine Replacement Therapy, Self-help materials, iQuit Mindfully; Behavioral · Drug
Lead sponsor: Georgia State University; Other
Eligibility: 18 Years and older
Enrollment: 504 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Smoking, Depression
Interventions: Smoking Cessation Treatment, Nicotine Replacement Therapy, CBASP; Behavioral · Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 16 Years and older
Enrollment: 91 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cigarette Smoking, Veterans
Interventions: Healthy Changes Nicotine Replacement Therapy (NRT), Cessation Treatment Nicotine Replacement Therapy (NRT), Cessation Treatment Counseling, Healthy Changes Counseling; Drug · Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2031
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Nicotine Dependence
Interventions: Sustained Care, Usual Care; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years and older
Enrollment: 422 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Smoking, Cigarette
Interventions: JUUL, Treatment As Usual; Device · Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 21 Years to 99 Years
Enrollment: 350 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Smoking
Interventions: nicotine replacement therapy and bupropion, smoking cessation counseling and referrals; Drug · Behavioral
Lead sponsor: Atlantic Health System; Other
Eligibility: 21 Years and older
Enrollment: 900 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Morristown, New Jersey

Conditions: Carcinoma In Situ, Current Smoker, Malignant Neoplasm, Primary Neoplasm, Recurrent Neoplasm, Smoking Cessation
Interventions: Behavioral, Psychological or Informational Intervention, Nicotine Replacement, Quality-of-Life Assessment, Survey Administration, Tobacco Cessation Counseling; Other · Drug
Lead sponsor: ECOG-ACRIN Cancer Research Group; Network
Eligibility: 18 Years and older
Enrollment: 306 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 42
States / cities: Anchorage, Alaska • Atlanta, Georgia • Augusta, Georgia + 32 more

Conditions: Cardiovascular Diseases, Heart Diseases, Hypertension
Interventions: Nicotine Replacement Therapy, Diet; Drug · Behavioral
Lead sponsor: Mark Vander Weg; Other
Eligibility: Not listed
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2011
U.S. locations: 2
States / cities: Iowa City, Iowa • Rochester, Minnesota

Conditions: Peripheral Artery Disease (PAD)
Interventions: Offer and Report Protocol; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 156 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 8
States / cities: Gainesville, Florida • Chicago, Illinois • Shreveport, Louisiana + 5 more

Conditions: COPD
Interventions: E-cigarette (EC), Nicotine Replacement Therapy (NRT), Smoking Harm Reduction Counseling Sessions; Other · Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 21 Years to 75 Years
Enrollment: 146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Smoking, Tobacco Use, Lung Cancer
Interventions: Nicotine patch and lozenges, Telephone counseling sessions, Access to a web-based video, Florida Tobacco Quitline; Drug · Behavioral
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Smoking Cessation
Interventions: Mailed nicotine replacement therapy, Text messaging, Brief advice; Drug · Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Smoking Cessation, Smoking, Cigarette, Smoking Reduction, Smoking, Smoking, Tobacco, Quitting Smoking
Interventions: 4 weeks of Nicotine lozenge, 8 weeks of Nicotine Replacement Therapy Patch, QuitAid, Smokefree TXT, Tobacco Quitline, 4 weeks of Nicotine Replacement Therapy Patch, 8 Weeks Nicotine Lozenge; Drug · Behavioral
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 768 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Smoking Cessation, HIV Infections
Interventions: Sense2Quit App; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Tobacco Cessation, Tobacco Abstinence, Tobacco Use, Tobacco Use Cessation, Tobacco Dependence
Interventions: Nicotine Replacement Therapy (NRT), Wellness Coaching; Drug · Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Smoking Cessation
Interventions: Nicotine Replacement Therapy (NRT), Questionnaire, Counseling, Self-Help Materials; Drug · Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2016
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Smoking Cessation
Interventions: Self-help materials, nicotine patch, Smartphone-delivered automated treatment, Counseling; Behavioral · Drug · Other
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 99 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Smoking Cessation
Interventions: Automated Mobile Contingency Management (CM), Standard Care (SC); Behavioral · Other
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years and older
Enrollment: 532 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Tobacco Dependence
Interventions: Innovative System, Standard Treatment Control (STC); Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 175 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: San Francisco, California

Search by objective public record fields.

Smoking Treatment in HIV Clinical Care Settings

Tech and Telephone Smoking Cessation Treatment for Young Veterans With PTSD

Smoking Cessation Using Motivational Therapy and Varenicline

Risk Perception Among Quitting Smokers

Longitudinal Studies of HIV-Associated Lung Infections and Complications (Lung HIV)

Mindfulness-based Smoking Cessation Enhanced With Mobile Technology

Smoking Cessation for Depressed Smokers

Evaluating an Innovative Tobacco Treatment Approach for Veterans in Substance Use Treatment

Smoking Cessation Following Psychiatric Hospitalization

Switching to a Vaping Device: Evaluating Risk Reduction Among Quitline Treatment Failures

Smoking Cessation Program: A Quality Improvement Trial in a Resident-Based Outpatient Clinic

Implementing a Virtual Tobacco Treatment for Cancer Patients in Community Oncology Practices

Preventing Weight Gain and Controlling Blood Pressure During Smoking Cessation in Hypertensive Smokers

Vascular Physician Offer and Report (VAPOR) Trial

Electronic Cigarettes as a Harm Reduction Strategy Among Patients With COPD

Project HEALS (Helping and Empowering pAtients for Living a Life Smoke-free

A Text Messaging Program for Smokers in Primary Care

Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

Development and Pilot Testing of the Sense2Quit App

Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness

Determinants of Smoking Cessation Among Latinos

Smartphone-delivered Automated Video-assisted Smoking Treatment for Patrons of a Food Resource Center

Mobile Contingency Management for Smoking Cessation

Tobacco Intervention in Buprenorphine Treatment