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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:10 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 429 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Nicotine replacement Clear all

Conditions: Tobacco Use Disorder
Interventions: nicotine transdermal system; Drug
Lead sponsor: New York University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 585 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 13
States / cities: Los Angeles, California • Tarzana, California • Miami, Florida + 8 more

Conditions: Newly Diagnosed Cancer Patients
Interventions: Hospital Counseling + Nicotine Replacement Therapy. questionaires, Hospital Counseling + Nicotine Replacement + Presurgical Scheduled Reduced Smoking, questionaires; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 204 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Cigarette Smoker, Tobacco Use Disorder
Interventions: Behavioral Intervention, Laboratory Biomarker Analysis, Nicotine Patch, Questionnaire Administration, Smoking Cessation Intervention; Behavioral · Other · Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 85 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Smoking Cessation
Interventions: Nicotine transdermal patch; Drug
Lead sponsor: University of Texas at Austin; Other
Eligibility: 23 Years to 60 Years · Male only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Smoking Cessation
Interventions: Nicotine (2 mg), Nicotine (4 mg); Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 19 Years to 55 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Electronic Nicotine Delivery Systems, Tobacco Products, Cigarette Smoking
Interventions: EQUIP, Standard Care; Behavioral
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 26 Years
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Endothelial Dysfunction
Interventions: Nicotine Replacement Therapy (NRT), Gamma-Tocopherol, Placebo, Smoking cessation; Other · Dietary Supplement · Behavioral
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years to 60 Years
Enrollment: 67 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Storrs, Connecticut

Conditions: Secondhand Smoke
Interventions: Quitline Delivered Treatment; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 18 Years and older
Enrollment: 484 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Tobacco Smoking
Interventions: Motivational Interviewing, Nicotine Replacement Therapy Sampling, Referral Only; Behavioral · Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 65 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Smoking Cessation
Interventions: WEB, Social Network, Nicotine Replacement Therapy (NRT); Behavioral
Lead sponsor: Truth Initiative; Other
Eligibility: 18 Years and older
Enrollment: 5,292 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Lung Cancer
Interventions: smoking cessation intervention, bupropion hydrochloride, nicotine, psychosocial assessment and care; Behavioral · Drug · Procedure
Lead sponsor: SWOG Cancer Research Network; Network
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2004
U.S. locations: 175
States / cities: Anniston, Alabama • Mobile, Alabama • Phoenix, Arizona + 115 more

Conditions: Tobacco Use Disorder
Interventions: ModafinilNicotine Replacement Therapy, Modafinil; Drug
Lead sponsor: Catherine Martin, MD; Other
Eligibility: 16 Years to 40 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2011
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Tobacco Use
Interventions: Behavioral and pharmacological support to reduce combustible tobacco use.; Behavioral
Lead sponsor: Rose Research Center, LLC; Industry
Eligibility: 21 Years and older
Enrollment: 100 participants
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Cigarette Smoking
Interventions: Group counseling and nicotine replacement, Group counseling, nicotine replacement, and text messaging support; Behavioral
Lead sponsor: RAND; Other
Eligibility: 18 Years to 25 Years
Enrollment: 77 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 3
States / cities: Los Angeles, California • Venice, California

Conditions: Tobacco Prevention, Environmental Tobacco Smoke Exposure, Tobacco Cessation
Interventions: LifeSkills Training, Healthy Lifestyle Behavior Choices, NRT and Motivational Interviewing (MI); Behavioral
Lead sponsor: Augusta University; Other
Eligibility: 8 Years and older
Enrollment: 688 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2014
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Nicotine Dependence
Interventions: nicotine patch (Nicoderm Committed Quitter (CQ), Habitrol), denicotinized cigarettes (Quest 3 cigarettes); Drug · Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years to 60 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: HIV/AIDS
Interventions: Storytelling Narrative Intervention; Combination Product
Lead sponsor: University of Massachusetts, Boston; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Smoking Cessation
Interventions: individualized counselor-led MI sessions, general health education session, NRT; Behavioral
Lead sponsor: Temple University; Other
Eligibility: 18 Years to 110 Years
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: ST+ABR, ST+SHAM, ST-only
Interventions: ST+ABR, ST+Sham, ST Only; Behavioral
Lead sponsor: University of Houston; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cigarette Smoking, Overweight, Obesity
Interventions: Weight gain prevention and smoking cessation, Smoking cessation; Behavioral
Lead sponsor: Consumer Wellness Solutions; Industry
Eligibility: 18 Years and older
Enrollment: 2,540 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Cigarette Smoking
Interventions: D-cycloserine, Nicotine Replacement Therapy (patch), Smoking Cue Exposure, Progressive Muscle Relaxation, Placebo; Drug · Behavioral
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 21 Years to 55 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Tobacco Use
Interventions: EX program; Behavioral
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 18 Years to 120 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Urbana, Illinois

Conditions: Tobacco Use Cessation, Cancer Prevention
Interventions: Nicotine Patch, Questionnaires, Carbon Monoxide (CO) Test, Health Education and Handouts, Culturally Tailored Reading Materials, Counseling Sessions; Drug · Behavioral · Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cigarette Smoking, Smoking Cessation
Interventions: Contingency Management (CM), Transdermal nicotine skin patches (i.e. Habitrol), Supportive Counseling; Behavioral · Drug · Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Durham, North Carolina

Search by objective public record fields.

Smoking Cessation Treatment With Transdermal Nicotine Replacement Therapy - 1

Smoking Cessation Intervention for Cancer Patients

Behavioral Activation Therapy and Nicotine Replacement Therapy in Increasing Smoking Cessation

Smoking Cessation and Sexual Health in Men

Nicotine Lozenge Bioequivalence Study

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

Impact of Smoking Cessation and γ-Tocopherol to Restore Vascular Endothelial Function

Parent eReferral to Tobacco Quitline

Tobacco and Socioeconomic Disadvantage

Improving Adherence to Web-Based Cessation Programs: A Social Network Approach

S0002 - A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone Surgery

Safety of Combining Modafinil and Nicotine Replacement Therapy in Treating Nicotine Dependent Adolescents

Comparative Tobacco Interventions for Individuals With Severe and Persisting Behavioral Health Disorders

Text Messaging-Based Smoking Cessation Program for Homeless Youth

The Impact of a Tobacco Control Intervention in African-American Families

Gender Differences in Response to Nicotine Replacement Therapy and De-Nicotinized Cigarettes

Storytelling Narrative Communication Intervention for Smoking Cessation in Women Living With HIV

Smoking Cessation in NYC

Shaping Habitual Impulses For a Tobacco-free Style

Comparative Effectiveness of Adding Weight Control to Smoking Cessation Quitlines

Effects of Nicotine Replacement Therapy and D-cycloserine on Nicotine Treatment Seekers

Be A Quitter: Illinois Small Business EX Program Dissemination

Project Impact 2: A Culturally Tailored Smoking Cessation Intervention for Latino Smokers

Contingency Management, Quitting Smoking, and ADHD