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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Nitrate-rich beetroot Juice Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Exercise Fatiguability in Older Adults: The Protective Effects of Dietary Nitrate Supplementation

NCT05313490
View directory record Official record
Conditions
Aging
Interventions
Beetroot Juice, Placebo Beetroot Juice
Dietary Supplement · Other
Lead sponsor
Marquette University
Other
Eligibility
60 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 23, 2022 · Synced Sep 4, 2026, 1:29 AM EDT
Active, not recruiting Phase 4 Interventional

Nitrite-boosting Therapy for Improving Physiological Function in Patients With Chronic Kidney Disease

NCT03826147
View directory record Official record
Conditions
Chronic Kidney Disease
Interventions
Nitrate-rich beetroot juice, Nitrate-depleted beetroot juice
Dietary Supplement
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
30 Years to 80 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 4, 2026, 1:29 AM EDT
Recruiting Phase 3 Interventional

Improving Mobility After Revascularization in Peripheral Artery Disease

NCT06686121
View directory record Official record
Conditions
Peripheral Artery Disease, Intermittent Claudication, Peripheral Vascular Disease, Mobility Limitation, Revascularization
Interventions
Home Based Exercise, Nitrate Rich Beetroot Juice, Attention Control, Placebo Beetroot Juice Without Nitrate
Behavioral · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
7
States / cities
Tucson, Arizona • Downey, California • Atlanta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 4, 2026, 1:29 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Postmenopausal Women and Their Endothelium

NCT03644472
View directory record Official record
Conditions
Postmenopausal Women
Interventions
nitrate rich beetroot juice, nitrate depleted beetroot juice
Drug
Lead sponsor
Penn State University
Other
Eligibility
Up to 70 Years · Female only
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 26, 2023 · Synced Sep 4, 2026, 1:29 AM EDT
Not listed Phase 1 Interventional

The Effects of Oral Inorganic Nitrate Supplementation on Lower Limb Perfusion During Exercise in Patients With PAD

NCT05036213
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Diseases
Interventions
BEET IT - Concentrate Beet root juice, BEET IT - Concentrate Beet root juice (nitrate depleted)
Drug
Lead sponsor
University of Virginia
Other
Eligibility
40 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Sep 4, 2026, 1:29 AM EDT
Completed Phase 2 Interventional

Effect of Inorganic Nitrates (Beetroot Juice) on Arterial Hemodynamics and Exercise Capacity

NCT01919177
View directory record Official record
Conditions
Heart Failure With Normal Ejection Fraction
Interventions
Nitrate rich beetroot juice, Nitrate depleted beetroot juice
Dietary Supplement
Lead sponsor
Corporal Michael J. Crescenz VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 27, 2015 · Synced Sep 4, 2026, 1:29 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effect of Beetroot Juice on Blood Pressure Regulation in Post Menopausal Women

NCT03380000
View directory record Official record
Conditions
Postmenopausal Women
Interventions
Beetroot juice, Beetroot juice placebo
Drug
Lead sponsor
Penn State University
Other
Eligibility
55 Years to 80 Years · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Sep 4, 2026, 1:29 AM EDT
Not listed Not applicable Interventional

The Effect of a Dietary Supplement Rich in Nitric Oxide in Patients Diagnosed With Primary Ciliary Dyskinesia.

NCT04489472
View directory record Official record
Conditions
Primary Ciliary Dyskinesia
Interventions
Beet-it Juice
Dietary Supplement
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
4 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Sep 4, 2026, 1:29 AM EDT
Completed Not applicable Interventional

Open Label Clinical Trial of Vascanox® HP on Nitric Oxide and Blood Pressure

NCT05928676
View directory record Official record
Conditions
Hypertension, Elevated Blood Pressure
Interventions
Vascanox® HP
Dietary Supplement
Lead sponsor
Calroy Health Sciences
Industry
Eligibility
25 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Sep 4, 2026, 1:29 AM EDT
Recruiting Phase 3 Interventional

SMART Exercise for PAD

NCT06032065
View directory record Official record
Conditions
Peripheral Arterial Disease, Aging, Peripheral Vascular Diseases, Walking, Difficulty
Interventions
Supervised Treadmill Exercise, Home-Based Exercise, Nitrate-rich beetroot Juice
Behavioral · Dietary Supplement
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
3
States / cities
Chicago, Illinois • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 4, 2026, 1:29 AM EDT
Recruiting Phase 2 Interventional

Response to Exercise and Nitric Oxide in PAD

NCT06657976
View directory record Official record
Conditions
Peripheral Artery Disease, Exercise, Intermittent Claudication, Nitric Oxide
Interventions
Supervised Treadmill Exercise, Attention Control, Nitrate-Rich Beetroot Juice + supervised exercise therapy, Placebo + supervised exercise therapy
Behavioral · Combination Product
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 4, 2026, 1:29 AM EDT
Completed Early Phase 1 Interventional

Nitrate Supplementation and Cerebrovascular and Cognitive Function in Metabolic Syndrome

NCT05532423
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Beetroot Juice - Active, beetroot juice - Placebo
Drug
Lead sponsor
Penn State University
Other
Eligibility
55 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2025 · Synced Sep 4, 2026, 1:29 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men

NCT07161973
View directory record Official record
Conditions
Mitochondrial Energetics, Dietary Nitrate, Disuse Atrophy (Muscle) of Lower Leg
Interventions
Beetroot Juice - Active, Placebo Beetroot Juice Without Nitrate
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 44 Years · Male only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 4, 2026, 1:29 AM EDT
Terminated Not applicable Interventional

Effects of Dietary Nitrate in Women With Secondary Amenorrhea

NCT07019129
View directory record Official record
Conditions
Secondary Amenorrhea
Interventions
Beetroot Juice - Active, Placebo Beetroot Juice Without Nitrate
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 4, 2026, 1:29 AM EDT
Not yet recruiting Not applicable Interventional

Inorganic Nitrate as a Treatment for ANOCA: NO-ANOCA

NCT06948201
View directory record Official record
Conditions
Coronary Microvascular Dysfunction (CMD), Angina Patients With Non-obstructive Coronary Artery Disease
Interventions
70mL Nitrate Rich Beetroot Juice followed by placebo (Nitrate depleted beetroot juice), Placebo (70 mL Nitrate depleted beetroot juice) followed by 70mL Nitrate Rich Beetroot Juice
Dietary Supplement
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 28, 2025 · Synced Sep 4, 2026, 1:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Influence of Early Menopause on Sympathetic Activation and Cardiovascular Function in Older Women

NCT03692572
View directory record Official record
Conditions
Early Menopause, Menopause
Interventions
Nitrate supplementation, placebo
Dietary Supplement
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
60 Years to 70 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Sep 4, 2026, 1:29 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Inorganic Nitrate and Intensity of Exercise on Cardiovascular Health in Post-Menopausal Females

NCT05221905
View directory record Official record
Conditions
Vascular Dilation, Arterial Stiffness
Interventions
BEET IT - Concentrate Beet root juice, BEET IT - Concentrate Beet root juice (nitrate depleted)
Drug
Lead sponsor
University of Virginia
Other
Eligibility
45 Years to 75 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Sep 4, 2026, 1:29 AM EDT
Completed Phase 2 Interventional Results available

Nitrite Supplementation in Long COVID Patients

NCT05618574
View directory record Official record
Conditions
Long COVID, Cardiorespiratory Fitness
Interventions
140 ml per day of Beet-It nitrate beverage (James White Drinks Ltd., Ipswich, UK), 210 ml of nitrate-depleted placebo
Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 4, 2026, 1:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Nitrate-rich Fruit and Vegetable Supplement on Blood Pressure

NCT03486145
View directory record Official record
Conditions
High Blood Pressure, Flow Mediated Dilation
Interventions
fruit and vegetable juice supplement, Placebo
Dietary Supplement
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 40 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 2, 2018 · Synced Sep 4, 2026, 1:29 AM EDT
Recruiting Not applicable Interventional

Interaction Between Inorganic Nitrate Supplementation and Metformin in Individuals With Prediabetes

NCT07131384
View directory record Official record
Conditions
Males, Females, Sedentary, Metformin, Prediabetes
Interventions
Dietary Supplement: Inorganic Nitrate (Beetroot juice), Dietary supplement: Placebo (Nitrate-depleted beetroot juice)
Dietary Supplement
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 4, 2026, 1:29 AM EDT
Completed Not applicable Interventional

Effect of Beet Juice Supplementation on Vascular and Inspiratory Muscle Function

NCT04920799
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Nitrate rich beetroot juice, Nitrate depleted beetroot juice
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
60 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 4, 2026, 1:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of the Combination of Nitrate and Caffeine on Critical Power In Trained Male Cyclists

NCT07501806
View directory record Official record
Conditions
Exercise Performance of Fit Athletes, Exercise Performance, Cycling Performance
Interventions
Dietary Nitrate, Caffeine, Placebo
Dietary Supplement · Other
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 4, 2026, 1:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nitrate Supplementation and Muscle Blood Flow

NCT03459027
View directory record Official record
Conditions
Vasodilation, Blood Pressure, Active Hyperemia, Aging
Interventions
Super Beets, Beetroot powder
Dietary Supplement
Lead sponsor
University of Iowa
Other
Eligibility
60 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Sep 4, 2026, 1:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nitrate Supplementation and Exercise Tolerance in Patients With Type 2 Diabetes

NCT02804932
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Super Beets, Super Beets Placebo
Dietary Supplement · Other
Lead sponsor
Darren P Casey
Other
Eligibility
40 Years to 77 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 27, 2024 · Synced Sep 4, 2026, 1:29 AM EDT