- Conditions
- Major Depressive Disorder, Treatment Resistant Depression
- Interventions
- Nitrous oxide gas for inhalation, Placebo
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 30
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- PTSD
- Interventions
- Nitrous Oxide, Midazolam, Nitrogen, Oxygen, Saline
- Drug
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Major Surgery, Coronary Artery Disease
- Interventions
- Vitamin B12 and folic acid, Nitrous oxide and placebo, standard of care
- Drug · Other
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 687 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2016
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Major Depressive Disorder, Depression, Mood Disorders, Suicidal Ideation
- Interventions
- Nitrous Oxide, Placebo gas
- Drug
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2026
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- Nitrous oxide 10% & placebo, Nitrous oxide 20% & placebo, Nitrous oxide 30% & placebo, Nitrous oxide 40% and placebo
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 32 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1996 – 1997
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Post-Amputation Phantom Limb Pain
- Interventions
- Cryoneurolysis, Sham Comparator
- Device
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 144 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 6
- States / cities
- Palo Alto, California • San Diego, California • Gainesville, Florida + 2 more
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 30% Nitrous oxide, 0.4% Sevoflurane, 0.2% sevoflurane, Placebo
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- Not listed
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1996 – 1999
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Contraceptive Devices, Long-Acting Reversible Contraception, Analgesia, Adolescent Health, Gynecology
- Interventions
- Nitrous oxide gas for inhalation, Oxygen Gas for Inhalation
- Drug
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 14 Years to 24 Years · Female only
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Tinnitus
- Interventions
- Nitrous oxide gas for inhalation, Placebo gas for inhalation
- Drug
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Labor Pain, Induced; Birth
- Interventions
- Nitrous oxide, Oxygen
- Drug
- Lead sponsor
- Jefferson Drapkin
- Other
- Eligibility
- 18 Years to 45 Years · Female only
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Brooklyn, New York
- Conditions
- Asthma
- Interventions
- Antipyrine-benzocaine otic solution, Glycerin with Oxyquinoline Sulfate
- Drug · Other
- Lead sponsor
- Global United Pharmaceutical Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Augusta, Georgia
- Conditions
- Healthy
- Interventions
- Nitrous Oxide Gas for Inhalation
- Drug
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 21 Years to 40 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Cardiovascular Abnormalities
- Interventions
- B12-Folic Acid, nitrous oxide, Nitrous oxide (NO) and placebo, Placebo, oxygen nitrogen
- Drug · Other
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Rib Fracture, Rib Fracture Multiple
- Interventions
- Cryoneurolysis, Local anesthetic peripheral nerve block, Sham Cryoneurolysis, Sham peripheral nerve block
- Device · Procedure
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 5
- States / cities
- La Jolla, California • Bethesda, Maryland • Boston, Massachusetts + 1 more
- Conditions
- ACL Reconstruction (ACLR) With a Bone-patellar Tendon-bone (BPTB) Autograft
- Interventions
- Pacira Iovera Cryoneurolysis device, Placebo/Sham device
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Overactive Bladder, Neurogenic Bladder, Urge Incontinence, Pain, Urinary Incontinence, Urinary Bladder, Overactive, Urinary Bladder, Neurogenic, Urinary Bladder Neurogenesis, Urinary Incontinence, Urge, Pelvic Floor Disorders
- Interventions
- Pro-Nox Nitrous Oxide/Oxygen Delivery System, Standard Care for Bladder Botox Injection, Sham Mask
- Drug · Other
- Lead sponsor
- TriHealth Inc.
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 96 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 2
- States / cities
- Cincinnati, Ohio
- Conditions
- Safety and Efficacy of Intranasal Dexmedetomidine
- Interventions
- Dexmedetomidine, Midazolam Hydrochloride, Nitrous Oxide
- Drug
- Lead sponsor
- Bon Secours Pediatric Dental Associates
- Other
- Eligibility
- 3 Years to 6 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Contraception
- Interventions
- IUD insertion, Povidone-Iodine, Chlorhexidine, Oxygen, Nitrous oxide
- Procedure · Drug · Other
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 12 Years and older · Female only
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Amnesia
- Interventions
- Nitrous Oxide 0%, Nitrous oxide 33%, Nitrous oxide 66%
- Drug
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- 6 Years to 12 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Suicidal Ideation, Major Depressive Disorder, Treatment Resistant Depression
- Interventions
- Nitrous oxide gas for inhalation, Placebo
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years to 65 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 30% N2O, 0.2% isoflurane, 0.4% isoflurane, 100% oxygen
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 32 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1994 – 1996
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Adenotonsillitis, Tonsillitis
- Interventions
- Acetaminophen (paracetamol), Normal Saline Flush, Midazolam, Sevoflurane, Nitrous Oxide/Oxygen, Propofol, Morphine, Ondansetron, Dexamethasone
- Drug
- Lead sponsor
- Nationwide Children's Hospital
- Other
- Eligibility
- 2 Years to 9 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Abortion in First Trimester
- Interventions
- Nitrous oxide administration
- Other
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 140 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Preeclampsia, Labor, Premature
- Interventions
- Monoket Pill, Placebo
- Drug
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years to 42 Years · Female only
- Enrollment
- 176 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Columbus, Ohio