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ClinicalTrials.gov public records Last synced Sep 25, 2026, 8:38 PM EDT

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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: No Acoustic Stimulation (SHAM) Clear all
Recruiting Not applicable Interventional

Acoustic Stimulation, Sleep, and Cognitive-Emotional Processes in Young Adults With Anxiety and Depression Symptoms

NCT05802004
View directory record Official record
Conditions
Acoustic Stimulation
Interventions
Acoustic Stimulation (STIM), No Acoustic Stimulation (SHAM), Daily acoustic stimulation (STIM2), No daily acoustic stimulation (SHAM2)
Device
Lead sponsor
Michelle Stepan
Other
Eligibility
18 Years to 25 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 25, 2026, 8:38 PM EDT
Recruiting Not applicable Interventional

Sleep Architecture & Cognition in Focal Epilepsy

NCT05794295
View directory record Official record
Conditions
Focal Epilepsy
Interventions
Acoustic Stimulation (AS), SHAM Stimulation
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 25, 2026, 8:38 PM EDT
Completed Not applicable Interventional Results available

Pilot Study Comparing the Effectiveness of Two Different Methods of Acoustic Stimulation

NCT03600194
View directory record Official record
Conditions
Sleep Deprivation, Insufficient Sleep Syndrome, Healthy
Interventions
PowerSleep Stim, Northwestern Stim, PowerSleep Sham, NorthWestern Sham
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 50 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 13, 2021 · Synced Sep 25, 2026, 8:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sounds Locked to ElectroEncephalogram Phase For the Acceleration of Sleep Onset Time

NCT05743114
View directory record Official record
Conditions
Sleep, Sleep Disturbance
Interventions
Elemind Neuromodulation (ENMod)
Device
Lead sponsor
Elemind Technologies, Inc.
Industry
Eligibility
21 Years to 55 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 19, 2024 · Synced Sep 25, 2026, 8:38 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

TMS-Induced LH Response in Healthy Women in Luteal Phase

NCT07363421
View directory record Official record
Conditions
Healthy Women
Interventions
Transcranial Magnetic Stimulation Active, Transcranial Magnetic Stimulation Sham
Device
Lead sponsor
The City College of New York
Other
Eligibility
22 Years to 40 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Sep 25, 2026, 8:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of SmartSleep Technology for Improving the Efficiency and Restorative Quality of Sleep in Healthy Adults

NCT03911154
View directory record Official record
Conditions
Sleep
Interventions
Philips SmartSleep Technology--Continuous Fixed Interval modality, Philips SmartSleep Technology--Block modality, Philips SmartSleep Technology--In-Phase Adjustable modality
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 55 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Sep 25, 2026, 8:38 PM EDT
Not yet recruiting Not applicable Interventional

Ultrasound for Peripheral Nerve Modulation

NCT07572591
View directory record Official record
Conditions
Neuropathic Pain, Chronic Pain
Interventions
Ultrasound, Sham (No Treatment)
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 25, 2026, 8:38 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Auditory Stimulation Effect on Brain Oscillations and Sleep Dependent Learning

NCT06688526
View directory record Official record
Conditions
Healthy Control
Interventions
Quiet Sounds, Sham Sounds
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 25, 2026, 8:38 PM EDT
Recruiting Not applicable Interventional

Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease

NCT07207122
View directory record Official record
Conditions
Parkinson Disease
Interventions
Gen0Bh Transcranial Focused Ultrasound System (Active), Gen0Bh Transcranial Focused Ultrasound System (Sham)
Device
Lead sponsor
Sanmai Technologies PBC dba Sanmai
Industry
Eligibility
22 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Tucson, Arizona • Santa Monica, California • Gainesville, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 25, 2026, 8:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Closed Loop Acoustic Stimulation During Sedation With Dexmedetomidine

NCT04206059
View directory record Official record
Conditions
Sleep, Sedation Complication
Interventions
MRI, Quantitative Sensory Testing (QST), Home sleep study, Acoustic stimulation (65 decibels or db) up-slope of EEG with QST, Acoustic stimulation (65db) down-slope of EEG with QST, 0 db with QST, Dexmedetomidine, Breathe-Squeeze Task
Radiation · Diagnostic Test · Other + 1 more
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 40 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 25, 2026, 8:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Slow-wave Enhancement in Adults Aged 30-49

NCT04611828
View directory record Official record
Conditions
Sleep
Interventions
Philips SmartSleep
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
30 Years to 49 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Sep 25, 2026, 8:38 PM EDT
Active, not recruiting Not applicable Interventional

Acoustic Stimulation for Seizure Suppression

NCT03198494
View directory record Official record
Conditions
Epilepsy
Interventions
Acoustic 1Hz Stimulation, Sham Background Noise
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 60 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 25, 2026, 8:38 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurophysiologic Correlates of Hypersomnia

NCT01719315
View directory record Official record
Conditions
Major Depressive Disorder, Primary Hypersomnia, Bipolar Disorder, Narcolepsy, Primary Insomnia
Interventions
Acoustical slow wave induction
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 60 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 23, 2018 · Synced Sep 25, 2026, 8:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using Combined EEG and Non-invasive Brain Stimulation to Examine and Improve Reward Functioning in Opioid Use Disorder

NCT04432493
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Active repetitive transcranial magnetic stimulation (rTMS), Sham repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
Rutgers University
Other
Eligibility
18 Years to 55 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced Sep 25, 2026, 8:38 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Acoustic Stimulation During Restricted Sleep After Sleep Deprivation

NCT05309473
View directory record Official record
Conditions
Sleep Deprivation, Sleep Restriction, Acoustic Stimulation, Performance, Alertness
Interventions
Philips SmartSleep Acoustic Stimulation Device, Sham (no Acoustic Stimulation)
Device
Lead sponsor
Walter Reed Army Institute of Research (WRAIR)
Federal
Eligibility
18 Years to 39 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Sep 25, 2026, 8:38 PM EDT