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Showing 1–24 of 25 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: No blood flow restriction training Clear all
Completed Not applicable Interventional

Trial of Neurostimulation and Blood Flow Restriction for PFPS in Active Duty

NCT04086615
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
NMES and exercise supplemented with high BFR, NMES and exercise supplemented with low BFR
Device
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 44 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Fort Campbell North, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 5, 2022 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lower Extremity BFR-randomized Controlled Trial Healthy Volunteers

NCT05868304
View directory record Official record
Conditions
Healthy
Interventions
BFR, Stanard strengthening program.
Device · Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Influences of Single Chamber Vs. Multi-chamber Blood Flow Restriction Cuffs with Bicep Curls

NCT06754618
View directory record Official record
Conditions
Blood Vessel Disease, Muscle Edema
Interventions
Delfi
Device
Lead sponsor
Salisbury University
Other
Eligibility
18 Years to 40 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Salisbury, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 31, 2024 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction and Creatine Supplementation in Women

NCT05877417
View directory record Official record
Conditions
Physical Inactivity
Interventions
Creatine Monohydrate, Blood Flow Restriction, Exercise
Dietary Supplement · Device · Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blood Flow Restriction Training for The Shoulder

NCT04540367
View directory record Official record
Conditions
Healthy
Interventions
Blood flow restriction therapy
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Autoregulated and Non-autoregulated Blood Flow Restrictive Exercise on Indices of Arterial Stiffness

NCT05719090
View directory record Official record
Conditions
Arterial Stiffness, Healthy Lifestyle
Interventions
Delfi Personal Tourniquet Systems
Device
Lead sponsor
Salisbury University
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salisbury, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 25, 2026, 11:04 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Blood-Flow Restriction Exercise Following a Knee Replacement

NCT04018638
View directory record Official record
Conditions
Knee Injuries, Knee Osteoarthritis, Knee Arthritis
Interventions
B-FREE
Other
Lead sponsor
Michigan Technological University
Other
Eligibility
40 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Houghton, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting Not applicable Interventional

The Impact of Blood Flow Restriction Training in Adolescents After ACL Reconstruction: A Randomized Controlled Trial

NCT05754632
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries, Knee Injuries, Quadriceps Muscle Atrophy
Interventions
Blood Flow Restriction using Delfi Personalized Tourniquet System
Device
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Following Hip Arthroscopy

NCT04113759
View directory record Official record
Conditions
Labral Tear, Glenoid, Femoral Acetabular Impingement
Interventions
Blood Flow Restriction Rehabilitative Therapy, Sham BFR Rehabilitative Therapy
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional

Blood Flow Restriction Exercise Study

NCT02868021
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Strength testing, Short Physical Performance Battery (SPPB), Six-minute walk (SMW), Numerical pain scale, Self-assessed function, Muscle biopsies, Determination of 1 Repetition Maximum (1-RM), Blood flow restriction exercise, Borg CR10 scale
Device · Behavioral · Procedure
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional

Use of Blood Flow Restriction (BFR) Therapy in Post-operative Rehabilitation Following Distal Biceps Tendon Repair

NCT04503421
View directory record Official record
Conditions
Bicep Tendon Rupture
Interventions
Blood Flow Restriction Therapy
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 7, 2023 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting Not applicable Interventional

Evaluating the Efficacy of Blood Flow Restriction Therapy in a Randomized Clinical Trial for Postoperative Rehabilitation Following Ankle Ligament Reconstruction

NCT07451210
View directory record Official record
Conditions
Ankle Reconstruction, Blood Flow Restriction Therapy, Physical Therapy
Interventions
blood flow restriction
Device
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
5
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Enrolling by invitation No phase listed Observational

Blood Flow Restriction Following ACLR w/Quad Autograft

NCT06636045
View directory record Official record
Conditions
Autografts, Blood Flow Restriction Therapy, Rehabilitation Outcome, Quadriceps Muscle Strength, Anterior Cruciate Ligament Reconstruction
Interventions
Not applicable- observational study
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
14 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional Results available

The Back Exercises to Neutralize Disability Study

NCT02308189
View directory record Official record
Conditions
Low Back Pain
Interventions
Exercise with blood flow restriction, Exercise
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
18 Years to 50 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Personalized Blood Flow Restriction for Anterior Cruciate Ligament Rehabilitation

NCT04635579
View directory record Official record
Conditions
Anterior Cruciate Ligament Tear
Interventions
Blood flow restriction
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 27, 2022 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction (BFR) Training on the Ulnar Collateral Ligament (UCL)

NCT06664827
View directory record Official record
Conditions
Healthy, Healthy Male and Female Subjects, Healthy Volunteers
Interventions
Delfi PTS Blood Flow Restriction Tourniquet System
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 21, 2025 · Synced Sep 25, 2026, 11:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Influences of Single Chamber vs. Multi-chamber Blood Flow Restriction Cuffs

NCT06276673
View directory record Official record
Conditions
Blood Vessel Disease, Muscle Edema
Interventions
Delfi
Device
Lead sponsor
Salisbury University
Other
Eligibility
18 Years to 40 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Salisbury, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 25, 2024 · Synced Sep 25, 2026, 11:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Autoregulated and Non-autoregulated Blood Flow Restrictive Bicep Curls

NCT05748821
View directory record Official record
Conditions
Arterial Stiffness, Healthy Lifestyle
Interventions
Delfi Personal Tourniquet Systems
Device
Lead sponsor
Salisbury University
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Salisbury, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting Not applicable Interventional

REVASC-PAD: REstricted VASCular Exercise for Peripheral Arterial Disease - A Feasibility Study at University of Tennessee Medical Center

NCT07223437
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Blood Flow Restriction Cuff System, Low-load Resistance Training, High-load Resistance Training
Behavioral
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional Results available

Blood Flow Restriction Following ACL Reconstruction

NCT03758755
View directory record Official record
Conditions
Anterior Cruciate Ligament Rupture
Interventions
Blood Flow Restriction Therapy, ACL Reconstruction rehabilitation
Device · Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
13 Years to 50 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training for People With Disabilities

NCT06441422
View directory record Official record
Conditions
Weakness, Muscle
Interventions
Blood flow restriction training, No blood flow restriction training
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 25, 2026, 11:04 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training on Upper Extremity Grip Strength

NCT06535373
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Blood flow restriction
Other
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years to 35 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Limb Occlusion Pressure Attainment on Cardiovascular, Perceptual, and Performance Responses

NCT06718582
View directory record Official record
Conditions
Blood Flow Restriction (BFR) Training Effects, Arterial Stiffness, Blood Pressure, Muscle Morphology, Perceptions
Interventions
Delfi Training Device
Device
Lead sponsor
Teri Herberger
Other
Eligibility
18 Years to 40 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Salisbury, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Sep 25, 2026, 11:04 PM EDT
Completed Not applicable Interventional

Low-Load Blood Flow Restriction on Patients With Multiple Sclerosis

NCT05177952
View directory record Official record
Conditions
Training Study, Multiple Sclerosis, Blood Flow Restriction
Interventions
Blood Flow Restriction, Standard of Care
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Sep 25, 2026, 11:04 PM EDT