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ClinicalTrials.gov public records Last synced Nov 7, 2026, 9:12 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 553–576 of 871 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: No diet Clear all

Conditions: Esophageal Achalasia, Esophageal Spasm, Diffuse, Esophageal Motility Disorders
Interventions: peroral endoscopic myotomy, Botulinum toxin injection; Procedure
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Overweight, Type 2 Diabetes Mellitus, Type 1 Diabetes Mellitus
Interventions: Lifestyle Intervention, No Intervention; Other
Lead sponsor: Joslin Diabetes Center; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hepatitis C
Interventions: Rifaximin, Placebo; Drug
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Smoking, Smoking Cessation, Adherence, Nicotine Dependence, Motivation
Interventions: Short Term Combination Nicotine Replacement Therapy (patch + gum), Long Term Combination Nicotine Replacement Therapy (patch + gum), Intensive Maintenance Counseling, Cognitive Medication Adherence Counseling (CAM), Electronic Medication Monitoring Device (the Helping Hand) + Feedback, Automated Adherence Prompting Phone Calls; Drug · Behavioral
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 99 Years
Enrollment: 544 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Healthy
Interventions: Base diet + high beta-carotene tomato juice, Base diet + high lycopene tomato juice, Base diet + placebo beverage; Other
Lead sponsor: USDA Beltsville Human Nutrition Research Center; Federal
Eligibility: 21 Years to 75 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Beltsville, Maryland

Conditions: Diabetes Mellitus, Type 1, Overweight and Obesity
Interventions: Hypocaloric, low carbohydrate diet, Hypocaloric, moderate low fat diet, Mediterranean diet, no caloric restriction; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 19 Years to 30 Years
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 2
States / cities: Palo Alto, California • Chapel Hill, North Carolina

Conditions: Non-Alcoholic Fatty Liver Disease, Obesity
Interventions: Moderately carbohydrate-restricted diet, Fat-restricted diet; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 10 Years to 17 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Obesity
Interventions: incentives for dietary self-monitoring, incentives for interim weight loss, incentives for both; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 105 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Polycystic Ovary Syndrome
Interventions: Metformin, Dietary Restriction, Exercise Training; Drug · Behavioral
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 20 Years to 40 Years · Female only
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Obesity, Overweight
Interventions: Intermittent Fasting group, control group; Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 30 Years to 65 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Diastolic Heart Failure, Hypertensive Heart Disease
Interventions: DASH/sodium-restricted diet (DASH/SRD), Control Diet; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 50 Years and older
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Caloric Intake
Interventions: Variety, Non-Variety; Behavioral
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 3 Years to 6 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Intra-abdominal Fat, Metabolic Syndrome, High Cholesterol, Triglycerides High, Diet Habit, High Blood Sugar, Liver Fat, Dietary Modification, HDL Cholesterol, Low Serum, Cardiovascular Diseases, High Density Lipoprotein Deficiency, Low-density-lipoprotein-type, Cardiovascular Risk Factor, Diabetes
Interventions: Intervention Daily Avocado; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 25 Years and older
Enrollment: 1,008 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 4
States / cities: Loma Linda, California • Los Angeles, California • Boston, Massachusetts + 1 more

Conditions: Healthy, Impaired Glucose Tolerance
Interventions: Dietary supplement regimen, Dietary supplement and intermittent fasting regimen; Dietary Supplement · Other
Lead sponsor: Unicity International, Inc.; Industry
Eligibility: 30 Years to 69 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Addison, Illinois

Conditions: Cognition, Immunity
Interventions: Mango group; Dietary Supplement
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Fermented Vegetable Intake, Fermented Vegetable Acceptability, Gut Health, Gut Microbiome, Gastrointestinal Immune Function, Microbiome
Interventions: Fermented vegetable intervention; Other
Lead sponsor: USDA, Western Human Nutrition Research Center; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Davis, California

Conditions: Metabolic Disease, Obesity, Exercise
Interventions: Sodium Nitrate, Beetroot Juice no Nitrate, Beetroot Juice; Dietary Supplement
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 40 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Obesity, Energy Metabolism
Interventions: C (smoothies based on soy protein containing no additional calcium), B (smoothies based on soy protein containing calcium), A (smoothies based on dairy protein containing calcium); Dietary Supplement
Lead sponsor: Purdue University; Other
Eligibility: 12 Years to 15 Years
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004
U.S. locations: 1
States / cities: West Lafayette, Indiana

Conditions: Barrett's Esophagus, Obesity
Interventions: Omega-3 polyunsaturated fatty acids, Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 85 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Obesity
Interventions: Communications, Pricing, Combined (Communications & Pricing); Other
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 21 Years to 100 Years
Enrollment: 444 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Diabetes Type II
Interventions: Low Carbohydrate Diet, American Diabetes Association Diet, Mindfulness and Positive Affect Skills; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Healthy Volunteer
Interventions: Urolithin A, Placebo; Dietary Supplement
Lead sponsor: National Institute on Aging (NIA); NIH
Eligibility: 55 Years to 100 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Chronic Kidney Disease, Diet Interventions, Disease Prevention
Interventions: Immediate delivery of low-sodium DASH (Dietary Approaches to Stop Hypertension) diet group coaching plus hand-on cooking program, Delayed delivery of low-sodium DASH (Dietary Approaches to Stop Hypertension) diet group coaching plus hand-on cooking program; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Immune Surveillance
Interventions: Yeast Fermentate (EpiCor); Dietary Supplement
Lead sponsor: Cargill; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Klamath Falls, Oregon

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Peroral Endoscopic Myotomy Versus Botulinum Toxin Injection in Spastic Esophageal Disorders

Impact of Metabolic Health on Sperm Epigenetic Marks in Humans

Rifaximin to Prevent Recurrent HCV-Related Fibrosis After Liver Transplant

Evaluation of Treatments to Improve Smoking Cessation Medication Adherence

Novel Metabolites of Beta-Carotene and Lycopene

ACT1ON Phase 2 (SMART Pilot) and Phase 3 (Efficacy Trial Development)

Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents

Incentivizing Behavior Change Skills to Promote Weight Loss

Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS

Can Intermittent Fasting Mimic the Metabolic and Cardiovascular and Anti-aging Effects of Calorie Restriction?

Dietary Approaches to Stop Hypertension in 'Diastolic' Heart Failure 2 (DASH-DHF 2)

The Influence of Dietary Variety and Course Sequence on Fruit Intake in Preschool-Aged Children

Habitual Diet and Avocado Trial

Effects of an Intermittent Fasting and Dietary Supplement Regimen on Glycemic Variability

Immune and Cognitive Benefits of Mango Intake in Young Adults

Fermented Vegetables and Gut Microbiome Pilot Study

Determination of the Independent Effects of Beetroot Juice Components, Dietary Nitrate and Antioxidants, on Exercise Tolerance and Health Benefits in Individuals With Obesity

Calcium, Dairy, and Body Fat in Adolescents

Modulation of Esophageal Inflammation in Barrett's Esophagus by Omega-3 Fatty Acids

Multi-level Communications and Access Strategies to Improve the Food Environment

A Pilot Study of the Effects of Diet and Behavioral Interventions on Health in Diabetics

Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical Trial

Dine and DASH Into Wellness Pilot Study

EpiCor Clinical Study on Rapid Immune Modulating Effects