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Showing 241–264 of 266 matching trials from the live ClinicalTrials.gov search.
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Pre-Exposure Prophylaxis in YMSM

NCT01033942
Conditions
HIV
Interventions
coformulated emtricitabine (FTC) and tenofovir disoproxil fumarate (TDF) as PrEP, Placebo, Many Men, Many Voices (3MV)
Drug · Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 22 Years · Male only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Chicago, Illinois
Conditions
Depression, Anxiety, Mood
Interventions
Unified Protocol, Therapist Support
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mission Reconnect-Veterans and Their Partners to Manage Pain and PTSD (MR)

NCT03593772
Conditions
PTSD, Chronic Musculoskeletal Pain
Interventions
Mission Reconnect
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
730 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
3
States / cities
Tampa, Florida • Ann Arbor, Michigan • Seattle, Washington
Terminated Phase 4 Interventional Accepts healthy volunteers

Testing Pharmacological Therapies for Pregnant Smokers

NCT00224419
Conditions
Smoking, Pregnancy
Interventions
Motivational interviewing for smoking cessation, Cognitive behaviors therapy, CBT + NRT
Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2003
U.S. locations
2
States / cities
Durham, North Carolina • Fayetteville, North Carolina
Completed Not applicable Interventional Results available

Cleaner Air for Better Cardiac Biomarkers

NCT05379400
Conditions
Cardiovascular Diseases
Interventions
Portable air cleaner (PAC), Sham Portable air cleaner (PAC)
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Conditions
Music Exposure
Interventions
Music in Sport Based Youth Development, No Music Exposure
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
10 Years to 12 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Intensive Cognitive-Behavioral Therapy For Obsessive-Compulsive Disorder

NCT01368510
Conditions
Obsessive-Compulsive Disorder (OCD)
Interventions
Intensive Cognitive Behavioral Therapy (CBT), Waitlist
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Head Impact Exposure in Hawaii High School Football

NCT04020874
Conditions
Head Trauma, Cognitive Change, Confidence, Self, Sports Injuries in Children
Interventions
HuTT-2x, HuTT-4x
Behavioral
Lead sponsor
University of Massachusetts, Lowell
Other
Eligibility
14 Years to 19 Years
Enrollment
496 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Honolulu, Hawaii
Conditions
Language Development Disorders
Interventions
Language Intervention
Behavioral
Lead sponsor
Karla McGregor
Other
Eligibility
4 Years to 7 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Newark, Delaware
Conditions
HIV Infection
Interventions
FTC/TDF (Truvada®)
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
15 Years to 22 Years · Male only
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
12
States / cities
Los Angeles, California • Aurora, Colorado • Miami, Florida + 9 more
Active, not recruiting No phase listed Observational

Post-Marketing Study of Prucalopride Safety In Pregnancy

NCT04869280
Conditions
Chronic Idiopathic Constipation (CIC)
Interventions
No Intervention
Other
Lead sponsor
Takeda
Industry
Eligibility
Female only
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
La Jolla, California
Conditions
Sleep Deprivation, Critical Illness, Sleep-Wake Disorders, Bundle Care, Implementation Science, Delirium
Interventions
Nighttime noise & light reduction, Clustering patient-care interactions, Non-pharmacologic sleep aids, Daytime light exposure, Encourage out-of-bed activity, Medication management to support nighttime sleep
Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
62,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
7
States / cities
La Jolla, California • San Francisco, California • Orlando, Florida + 4 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Transmasculine One-on-One and Group Empowerment for Targeted HIV Reduction

NCT06182280
Conditions
HIV Infections, Adherence, Medication
Interventions
PrEP4T, LS4TM
Behavioral
Lead sponsor
Fenway Community Health
Other
Eligibility
18 Years and older · Male only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional

Safe Options for ACL Recovery

NCT04225468
Conditions
Anterior Cruciate Ligament Injuries, Opioid Use
Interventions
ACL Opioid Exposure Reduction Program
Behavioral
Lead sponsor
Karen Derefinko, PhD
Other
Eligibility
12 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Post Traumatic Stress Disorders, Unsafe Sex, Substance Use Disorders
Interventions
Cognitive Processing Therapy-Cognitive
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Toppenish, Washington
Conditions
Retinoid, Skin Aging, Epigenomics
Interventions
Night Cream Usage, No Night Cream Usage
Other
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
40 Years to 65 Years · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
High Point, North Carolina
Conditions
Muscular Atrophy, Spinal
Interventions
No Intervention
Other
Lead sponsor
Biogen
Industry
Eligibility
18 Years to 54 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
4
States / cities
Palo Alto, California • Boston, Massachusetts • Cambridge, Massachusetts + 1 more
Conditions
Smoking Cessation
Interventions
Personnel Training and Coaching Calls
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
1,094 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
49
States / cities
Newark, Delaware • Augusta, Georgia • Savannah, Georgia + 36 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Bright Light on Co-occurring Cancer-related Symptoms in Breast Cancer Survivors

NCT03304587
Conditions
Breast Cancer
Interventions
Polysomnography (PSG), Rectal thermistor 400 Series, Bright blue-green light, Dim red light, Digital foot candle datalogging light meter, Patient-Reported Outcomes Measurement Information System (PROMIS)-Cancer-Fatigue, Patient-Reported Outcomes Measurement Information System (PROMIS)-Sleep Disturbance, Patient-Reported Outcomes Measurement Information System (PROMIS)-Depression, Patient-Reported Outcomes Measurement Information System (PROMIS)-Physical Function, Pittsburgh Sleep Quality Index (PSQI), Center for Epidemiological Studies - Depression, Montreal Cognitive Assessment (MoCA), European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire (EORTC QLQ-C30), Daily Log
Diagnostic Test · Other
Lead sponsor
Michigan State University
Other
Eligibility
21 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
East Lansing, Michigan
Conditions
Obsessive-compulsive Disorder, Social Phobia, Generalized Anxiety Disorder, Specific Phobia, Separation Anxiety Disorder, Selective Mutism, Anxiety Disorder, Not Otherwise Specified
Interventions
Parent-Led Exposure Therapy, Treatment As Usual
Behavioral · Other
Lead sponsor
University of South Florida
Other
Eligibility
3 Years to 7 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
St. Petersburg, Florida
Completed No phase listed Observational Accepts healthy volunteers Results available

An MRI Investigation of Soft Tissues in Total Hip Arthroplasty

NCT01750606
Conditions
Tissue Reaction, Elevated Blood Ion Levels
Interventions
Not listed
Lead sponsor
Zimmer Biomet
Industry
Eligibility
Not listed
Enrollment
397 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
5
States / cities
Flint, Michigan • New Albany, Ohio • Columbia, South Carolina + 2 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Individually Tailored Lighting System to Improve Sleep in Older Adults

NCT01855126
Conditions
Sleep Disturbances
Interventions
Blue light, Red light
Other
Lead sponsor
Rensselaer Polytechnic Institute
Other
Eligibility
65 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Troy, New York
Completed Not applicable Interventional Accepts healthy volunteers

CRUSH-PrEP for Women Project

NCT02852226
Conditions
Sexually Transmitted Diseases, HIV
Interventions
Pre Exposure Prophylaxis, Characteristics of women who enroll, referral sources of women who enroll
Other · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Oakland, California
Conditions
Fetal Exposure Timing Unspecified
Interventions
There is no other intervention, only clinical treatment.
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Little Rock, Arkansas