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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:12 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 55 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Non-Bracing Clear all

Conditions: Spinal Cord Injury
Interventions: C-Brace II, Traditional Care KAFO intervention; Device
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Distal Radius Fractures
Interventions: Plaster Splint, Velcro Brace, Soft Dressing; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 2
States / cities: Fresno, California

Conditions: Thoracolumbar Burst Fracture
Interventions: Not listed
Lead sponsor: AO Innovation Translation Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 213 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 4
States / cities: San Diego, California • East Syracuse, New York • Philadelphia, Pennsylvania + 1 more

Conditions: Atrophy, Disuse, Muscle Atrophy, Muscular Disorders, Atrophic, Disuse Atrophy, Disuse Atrophy Muscle of Thigh
Interventions: Unilateral leg immobilization, Contralateral active leg; Other
Lead sponsor: United States Army Research Institute of Environmental Medicine; Federal
Eligibility: 18 Years to 39 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Natick, Massachusetts

Conditions: Healthy
Interventions: BOOT, HFC, SAC, HFC+BOOT, SAC+BOOT; Device
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 45 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Anterior Knee Pain
Interventions: Tri-Compartment Unloader Brace; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Scoliosis Idiopathic Adolescent Treatment, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis
Interventions: Standard of Care (SOC), Yoga; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 10 Years to 20 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Aseptic Revision Knee Arthroplasty, Stiffness Following Revision Knee Arthroplasty
Interventions: Knee immobilizer, No Knee Immobilizer; Device
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years and older
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Stroke, Acute, Gait Disorders, Neurologic
Interventions: Keeogo, Traditional Stair Training; Device · Other
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Balance Training Group, Control Group
Interventions: Balance training; Other
Lead sponsor: Old Dominion University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Norfolk, Virginia

Conditions: Thoracic Fracture, Lumbar Fracture, Compression Fracture of Thoracic Vertebral Body, Compression Fracture of Lumbar Spine, Burst Fracture of Thoracic Vertebra, Burst Fracture of Lumbar Vertebra
Interventions: Spinal Orthosis (LSO, TLSO), No orthosis; Other
Lead sponsor: St. Louis University; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Adolescent Idiopathic Scoliosis
Interventions: AbobotulinumtoxinA, Placebos, Custom Thoracolumbosacral Orthosis; Drug · Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 10 Years to 16 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Knee Osteoarthritis
Interventions: Patellofemoral realigning knee brace, Non-aligning knee brace; Device
Lead sponsor: Boston University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Interventions: KneeStim mobile rehabilitation assistance device; Device
Lead sponsor: Articulate Labs; Industry
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Cartilage Loss, Microfracture
Interventions: Unloader Bracing, Non-Bracing; Device
Lead sponsor: Stanford University; Other
Eligibility: 15 Years to 40 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Gait, Drop Foot, Chemotherapy-induced Peripheral Neuropathy, Acute Lymphocytic Leukemia, Pediatric, Rhabdomyosarcoma, Wilms Tumor
Interventions: Solid ankle foot orthotic, Resting night splint; Device
Lead sponsor: Children's Hospitals and Clinics of Minnesota; Other
Eligibility: 5 Years to 14 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 2
States / cities: Minneapolis, Minnesota • Memphis, Tennessee

Conditions: Pectus Excavatum
Interventions: Magnetic Mini-Mover Procedure (Magnimplant); Device
Lead sponsor: Michael Harrison; Other
Eligibility: 8 Years to 14 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2018
U.S. locations: 3
States / cities: Sacramento, California • San Francisco, California • Kansas City, Missouri

Conditions: Chronic Pain, Cancer Survivor, Opioid Dependence
Interventions: Multimodal pain care, Medication optimization, Buprenorphine rotation, Opioid tapering; Behavioral · Drug · Device + 1 more
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 99 Years
Enrollment: 294 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 2
States / cities: Indianapolis, Indiana • Ann Arbor, Michigan

Conditions: Distal Radius Fracture
Interventions: molded brace; Other
Lead sponsor: Foundation for Orthopaedic Research and Education; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Clubfoot Deformity
Interventions: Surgical, Non-Surgical, Non-surgical + surgical; Procedure
Lead sponsor: Texas Scottish Rite Hospital for Children; Other
Eligibility: Up to 18 Years
Enrollment: 2,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2029
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Migraine, Migraine Disorders, Migraine With Aura, Migraine Without Aura, Migraine, Classic
Interventions: Chiropractic Treatment; Other
Lead sponsor: Harvard University Faculty of Medicine; Other
Eligibility: 20 Years to 55 Years · Female only
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pediatric Femur Fracture
Interventions: Functional Brace, Hip Spica Cast; Device
Lead sponsor: Children's Hospital Los Angeles; Other
Eligibility: Up to 5 Years
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2025
U.S. locations: 2
States / cities: Los Angeles, California • Aurora, Colorado

Conditions: Diabetic Foot Ulcer, Diabetes Mellitus, Foot Ulcer, Foot Ulcer, Diabetic, Ulcer, Ulcer Foot, Ulcer, Leg, Ankle Ulcer
Interventions: Total Contact Soft Cast, Cam Boot; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Low Back Pain
Interventions: Inextensible LSO (stiff back support), Extensible LSO, a back support that is flexible, Standard of Care; Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: Charleston, South Carolina

Search by objective public record fields.

C-Brace II Spinal Cord Injury

Immobilization of Postoperative Distal Radius Fractures

Thoracolumbar Burst Fractures Study Comparing Surgical Versus Non-surgical Treatment

Molecular Mechanisms Underlying Anabolic Resistance to Protein Intake During Muscle Disuse

iWalk Hands Free Crutch

Spring Loaded Tri-Compartment Unloader Knee Brace Study

Yoga for Back Pain in Adolescent Scoliosis

Does Joint Immobilization Following Revision Total Knee Arthroplasty Improve Range of Motion Following Surgery?

The Effect of Powered-Knee Exoskeleton Assist on Stair Climbing in Acute CVA

Cross-Education for Chronic Ankle Instability

Effect of Bracing Versus No Bracing in Stable Thoracolumbar Compression and Burst Fractures

Dysport ® as an Adjunctive Treatment to Bracing in the Management of Adolescent Idiopathic Scoliosis

Knee Bracing for People With Patellofemoral Osteoarthritis

Dynamic Quadriceps Muscle Stimulation for Treatment of Patellofemoral Pain

Effects of Unloader Bracing in Clinical Outcome and Cartilage Physiology Following Microfracture of Chondral Defects

Impact of an Orthotic Intervention in Children With Peripheral Neuropathy

Multicenter Trial of Magnetic Mini-Mover for Pectus Excavatum

Better Options for Chronic Cancer Pain

Prospective, Observational Clinical Investigation of the Exos Reformable Brace

Prospective Evaluation of Treatment for Clubfoot

Integrative Migraine Pain Alleviation Through Chiropractic Therapy

Femur Fracture: Functional Bracing vs. Hip Spica Cast

Total Contact Soft Cast in Diabetic Foot Ulcers

Comparison of Extensible and Inextensible Lumbosacral Orthoses for Lower Back Pain