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ClinicalTrials.gov public records Last synced Oct 23, 2026, 7:29 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–162 of 162 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Non-Operative Pain Management Clear all

Conditions: Analgesia
Interventions: Epidural Catheter for Analgesia; Device
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Post Operative Pain
Interventions: Oxycodone, Tramadol and Oxycodone; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 560 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Shoulder Pain
Interventions: Tylenol and NSAIDS (Ibuprofen, diclofenac); Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Columbia, Maryland

Conditions: Low Back Pain, Chronic Pain, Surgery, Back Pain, Low, Back Pain Lower Back Chronic
Interventions: Standard Care (SC), Enriched Pain Management Pathway (EPM); Behavioral
Lead sponsor: Dan Rhon; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 267 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 3
States / cities: Honolulu, Hawaii • San Antonio, Texas • Tacoma, Washington

Conditions: Postoperative Nausea and Vomiting
Interventions: Automated recommendation at the start of the case, Automated notification at the start of surgery, Preoperative recommendations: by email, Automated notification at the end of surgery, Anesthesia Information Management System (AIMS), Perioperative Data Warehouse (PDW), General anesthesia, Elective surgery, Propofol, Sevoflurane, Isoflurane, Desflurane, Scopolamine, Droperidol, Haloperidol, Dexamethasone, Promethazine, Meclizine, Aprepitant, Metoclopramide, Fentanyl, Sufentanil, Alfentanil, Remifentanil, Morphine, Meperidine, Hydromorphone, Methadone, Oxycodone, Oxymorphone, Hydrocodone, Ketamine, Ondansetron, Granisetron, Dolasetron mesylate, Palonosetron, Tropisetron, Ramosetron; Procedure · Device · Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 27,034 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Acute Pain
Interventions: Mindfulness, Suggestion, Psychoeducation; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 727 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Orthopaedic Related Pain (Musculoskeletal Pain), Opioid, Pain, Pilot Study
Interventions: Discharge pain medication prescription; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Mammaplasty
Interventions: Breast Reconstruction (Mammaplasty), Pecs blocks, Exparel, Bupivacaine; Procedure · Device · Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Respiration Disorders
Interventions: Study to evaluate a Respiratory Monitoring System (RMS) with a Tracheal Sound Sensor (TSS) for detecting and predicting opioid induced respiratory Depression (OIRD).; Device
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Anterior Cruciate Ligament Reconstruction Rehabilitation, Dry Needling, Strength
Interventions: Dry Needling; Procedure
Lead sponsor: Children's Mercy Hospital Kansas City; Other
Eligibility: 10 Years to 20 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 3
States / cities: Kansas City, Kansas • Overland Park, Kansas • Kansas City, Missouri

Conditions: Opioid Use
Interventions: opioid-containing analgesic, two over-the-counter analgesics; Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 1,815 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 5
States / cities: Chicago, Illinois • Baltimore, Maryland • Ann Arbor, Michigan + 2 more

Conditions: Bupivacaine, Pain, Postoperative
Interventions: Bupivacaine, Liposomal bupivacaine, Placebos; Drug
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years and older · Female only
Enrollment: 132 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

Conditions: Macromastia (Symptomatic)
Interventions: Pectoral II Nerve Block, Post Operative Pain Relievers; Procedure · Drug
Lead sponsor: Carilion Clinic; Other
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Surgery
Interventions: Routine Elective Surgery- In patient or out patient elective surgery, Blood test for genetic testing, Drug-genetic Profile; Procedure · Diagnostic Test · Other
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 1,900 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: LC Pelvic Fracture
Interventions: LC fracture surgical fixation, LC fracture non-operative management; Procedure
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 80 Years
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 2
States / cities: Indianapolis, Indiana • Baltimore, Maryland

Conditions: Opioid Tapering
Interventions: Treatment as Usual (TAU), Telephonic Support (TS) Providers, DOTS Intervention; Other
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Breast Cancer, Postoperative Pain
Interventions: Liposomal bupivacaine, Bupivacaine with epinephrine, Morphine sulfate, Hydrocodone/acetaminophen, Diazepam; Drug
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 99 Years · Female only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Post Operative, Post Operative Analgesia, Urogynecologic Surgery
Interventions: Tizanidine, Standard-of-Care Therapy; Drug · Other
Lead sponsor: Hartford Hospital; Other
Eligibility: 18 Years to 89 Years · Female only
Enrollment: 186 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Hartford, Connecticut

Search by objective public record fields.

Epidural Anesthesia /Analgesia Versus PCA for Laparoscopic Complex Ventral Hernia Repair: A Randomized Controlled Trial

Efficacy And Safety Of Tramadol And Oxycodone Versus Oxycodone Monotherapy For Pain Control After Primary Total Knee And Total Hip Arthroplasty

Post-Operative Pain Control Following Shoulder Surgery

Non-pharmacological Treatment for Pain After Spine Surgery

Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis

Psychosocial Support for Pre-operative Pain and Distress

Two Post-Operative Pain Protocols at Discharge for Orthopaedic Patients

The Use of Pecs Blocks in Combination With Exparel in Breast Reconstruction Surgery

Respiratory Monitoring System That Detects & Predicts OIRD

Dry Needling and Quad Strength After Anterior Cruciate Ligament Reconstruction

Opioid Analgesic Reduction Study

Wound Infiltration of Liposomal Bupivacaine v Plain Bupivacaine for Post-Op Pain Control in Elective Cesarean Delivery

Pectoral Block in Breast Reduction for Pain Control

The ImPreSS Trial: Pharmacogenomic Decision Making at Time of Surgery

Pelvis RCT: Impact of Surgery on Pain in Lateral Compression Type Pelvic Fractures

Opioid Tapering After Hospital Discharge: Testing an Intervention to Improve Post-operative Opioid Prescribing

Liposomal Bupivacaine in Implant Based Breast Reconstruction

Postoperative Tizanidine Use in Pelvic Reconstructive Surgery: A Pilot Study