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Conditions: Prostate Cancer
Interventions: Weight Loss Program, Standard of Care; Other
Lead sponsor: Jill Hamilton-Reeves, PhD RD LD; Other
Eligibility: 50 Years to 72 Years · Male only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Chronic Pain, Opioids, Opioid-use Disorder
Interventions: I-COPE; Behavioral
Lead sponsor: University of Chicago; Other
Eligibility: 65 Years and older
Enrollment: 20,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Chronic Pain
Interventions: Brief Cognitive Behavioral Therapy for Chronic Pain (BCBT-CP), BCBT-CP Booster; Behavioral · Other
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years and older
Enrollment: 716 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 3
States / cities: Bethesda, Maryland • Fort Hood, Texas • San Antonio, Texas

Conditions: Smoking, Smoking Cessation
Interventions: TAMI Coach; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 440 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: San Francisco, California

Conditions: Sleep
Interventions: Sleep Smart Latino, Basic Sleep Hygiene and Child Health; Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 11 Years to 13 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Attention Deficit Hyperactivity Disorder
Interventions: Mindfulness-Based ADHD Treatment for Children, Goal-Standard Medication (Treatment as Usual); Behavioral · Biological
Lead sponsor: Yale University; Other
Eligibility: 7 Years to 13 Years
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Mental Health Screening Adherence
Interventions: Perinatal Psychoeducation Articles, Bi-weekly Perinatal Mental Health Screening, Chatbot-Guided Journaling, Perinatal-Focused Meditations, Themed Perinatal Learning Pathways; Behavioral
Lead sponsor: Poisera, Inc.; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Dietary Intervention, Produce Prescription, Chronic Disease Management, Social Needs Screening
Interventions: Culturally Tailored Cooking Classes, Prescription Produce Plan; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: BRCA1 Mutation, POLD1 Gene Mutation, CDKN2A Mutation, BRCA2 Mutation, POLE Gene Mutation, APC Gene Mutation, ATM Gene Mutation, MLH1 Gene Mutation, BARD1 Gene Mutation, MSH2 Gene Mutation, BRIP1 Gene Mutation, MSH6 Gene Mutation, CHEK2 Gene Mutation, PMS2 Gene Mutation, PALB2 Gene Mutation, EPCAM Gene Mutation, RAD51C Gene Mutation, BMPR1A Gene Mutation, RAD51D Gene Mutation, SMAD4, PTEN Gene Mutation, GREM1
Interventions: Intervention Arm At-risk Relative/ARR Contacts, MyGene Portal, Standard of Care; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 25 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 8
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Parkinson Disease
Interventions: MultiContext for PD Strategy Training, Standard of Care; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 40 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Depression
Interventions: RESCUE Problem Solving Intervention; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Not listed
Enrollment: 210 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2024
U.S. locations: 3
States / cities: Gainesville, Florida • Orlando, Florida • Tampa, Florida

Conditions: HIV, Heart Failure
Interventions: Exercise Intervention, Tailored Education sessions, Behavioral coaching, Mobile health support, General education; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 40 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Obesity, Overweight, Overnutrition, Nutrition Disorders, Signs and Symptoms
Interventions: Intervention Program; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 21 Years and older
Enrollment: 443 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Suicidal Thoughts and Behaviors, Social Isolation
Interventions: Qnnections, Enhanced Usual Care; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: San Diego, California

Conditions: Intellectual Disability, Developmental Disability, Axis I Diagnosis, Mental Illness, Covid19, Coronavirus
Interventions: Generic Best Practices, Tailored Best Practices; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 415 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: ADHD
Interventions: Classroom Behavior Support (CBS) Condition, Standard Problem Solving Consultation; Behavioral
Lead sponsor: Ohio University; Other
Eligibility: 5 Years to 12 Years
Enrollment: 125 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Athens, Ohio

Conditions: Social Needs Status, Unmet Health-Related Social Needs and Access to Community Resources, Primary Health Care and Access to Primary Care, Technology Use to Support Caregivers, Caregiver Burden, Health Status, Child and Infant Care, Preventative Care Services
Interventions: DAPHNE Chatbot Intervention, Standard HRSN Screening and Referral (Usual Care); Behavioral · Other
Lead sponsor: Emre Sezgin; Other
Eligibility: Not listed
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Smoking Cessation
Interventions: Personalization, Integration, Dynamic Tailoring, Message Intensity, Optimal-Adherence Text; Behavioral
Lead sponsor: Truth Initiative; Other
Eligibility: 18 Years and older
Enrollment: 1,485 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Aromatase Inhibitor, Musculoskeletal Symptoms, Postmenopausal Breast Cancer Survivors
Interventions: APA, Sham APA control, Education control; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Parent-Child Relations, Parenting Self Efficacy, Child Mental Health
Interventions: Project Support, Case Management Services; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 6 Years to 13 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Low Back Pain, Neck Pain
Interventions: Engagement of clinic leadership (System Intervention - Usual Care), Engagement of clinic leadership (System Intervention - STEPPT), Patient Registry (System Intervention - STEPPT), Delivery of Patient Education Materials (System Intervention - Usual Care), Delivery of Patient Education Materials (System Intervention - STEPPT), Referral Specialist Training (System Intervention - Usual Care), Patient Health Navigator Training (System Intervention - STEPPT), Care Navigation (System Intervention - STEPPT), Care navigation audit and feedback (System Intervention - STEPPT), Primary Care Provider training (Provider Intervention - STEPPT), Nurse/Medical Assistant Training (Provider Intervention - STEPPT), Provider feedback on PT referral and adherence (Provider Intervention - STEPPT), Patient education on spine pain condition (Patient Intervention - Usual Care), Patient education on spine pain condition (Patient Intervention - STEPPT), Patient Education on Physical Referral by Providers (Patient Intervention - Usual Care), Patient Education on Physical Referral by Providers (Patient Intervention - STEPPT), Electronic Patient Education on Physical Therapy Referral (Patient Intervention - STEPPT), Patient education on physical therapy referral by Referral Specialist (Patient Intervention - Usual Care), Patient education on physical therapy referral by Patient Health Navigator (Patient Intervention - STEPPT), Care Navigation (System Intervention - Usual Care), Monitoring of PT referral and adherence rates (System Intervention - STEPPT), Monitoring of PT referral and adherence rates (System intervention - Usual Care); Behavioral
Lead sponsor: San Diego State University; Other
Eligibility: 18 Years and older
Enrollment: 17,587 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: San Diego, California

Conditions: Head and Neck Cancer
Interventions: educational materials; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Atrial Fibrillation (AF)
Interventions: discontinue anticoagulation therapy, Anticoagulant drugs, Catheter Ablation; Behavioral · Drug · Procedure
Lead sponsor: China National Center for Cardiovascular Diseases; Government
Eligibility: 18 Years and older
Enrollment: 3,160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Mild Traumatic Brain Injury
Interventions: TEaM Intervention, Standard of Care; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 5 Years and older
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 3
States / cities: Atlanta, Georgia

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Energy Balance for Prostate Cancer Survivorship

I-COPE Study: Opioid Use and Pain Management in Older Adults

Chronic Pain Management In Primary Care Using Behavioral Health Consultants

Technology Assisted Motivational Interviewing

A Sleep Hygiene Intervention to Improve Sleep Quality in Urban, Latino Middle School Children - Phase 2

Mindfulness-Based ADHD Treatment for Children: a Feasibility Study

Evaluating Screening Adherence Between Moment for Parents App and Attention Control

Promoting Nutrition Security and Chronic Disease Management Through a Produce Prescription Program

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Feasibility and Effect of a Strategy-Based Cognitive Intervention for Parkinson Disease

Spanish Intervention for Caregivers of Veterans With Stroke

Proof-of-concept of a Behavioral Intervention to Improve the Cardiovascular Health of People Living With HIV

Balance: A Pragmatic Trial of a Digital Health Intervention to Prevent Weight Gain in Primary Care

Qnnections: Refinement and Pilot Trial of a Suicide Prevention Intervention to Increase Social Connection

Best Practices to Prevent COVID-19 Illness in Staff and People With Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Classroom Behavior Support (CBS) Project

AI-Based Personalized Health and Self-Care

Optimizing Text Messaging to Improve Adherence to Web-Based Cessation Treatment

Auricular Point Acupressure to Self-Manage Chronic Pain or Aromatase Inhibitor Musculoskeletal Symptoms in Breast Cancer Survivors: Effectiveness and Scientific Underpinnings

Examining Whether Project Support Works

Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT)

Studying Survivorship Care Plans in Head and Neck Cancer

Discontinuation of Anticoagulations After Successful Catheter Ablation of Atrial Fibrillation

TBI Evaluation and Management (TEaM)