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ClinicalTrials.gov public records Last synced Nov 14, 2026, 9:24 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 161 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Normal Saline (NS) Clear all

Conditions: Subarachnoid Hemorrhage
Interventions: desferrioxamine (DFO), placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Prostate Cancer, Lower Urinary Tract Symptoms, Radioactive Seed Implantation
Interventions: Botox injection, Saline injection; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: Ends 2012
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Alopecia Areata, Scarring Alopecia
Interventions: tSVF by lipoaspiration, PRP Concentration, Emulsification tSVF, cSVF isolation and concentration, cSVF in Normal Saline IV; Procedure
Lead sponsor: Regeneris Medical; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2025
U.S. locations: 3
States / cities: Irvine, California • North Attleboro, Massachusetts • Stevensville, Montana

Conditions: Injuries, Shock, Traumatic
Interventions: normal saline control, vasopressin; Drug
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years and older
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Radiocontrast Nephropathy
Interventions: N-Acetylcysteine (NAC), 0.9% Sodium-chloride; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 120 Years
Enrollment: 399 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cancer
Interventions: Normal Saline Group, Heparin Group; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 142 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Breast Cancer, Non-Hodgkin's Lymphoma
Interventions: Mesna, Saline, Doxorubicin, Cyclophosphamide; Drug
Lead sponsor: Mara Chambers; Other
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Acute Myeloid Leukemia
Interventions: Gemtuzumab ozogamicin, Mitoxantrone, Etoposide; Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 70 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Hypertrophic Scar
Interventions: PRP Injection, Saline Injection; Biological · Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 70 Years
Enrollment: 3 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Pain
Interventions: Ketamine, Placebo; Drug
Lead sponsor: The Brooklyn Hospital Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Pediatric Cardiac Surgery, Complication of Extracorporeal Circulation
Interventions: Tranexamic acid, Epsilon Aminocaproic Acid; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 3 Months to 17 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Oak Lawn, Illinois

Conditions: Peripheral Artery Disease
Interventions: Contrast Injection, Dextran Injection, CO2 Injection, Heparinized Normal Saline Injection; Procedure
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Malignant Rhabdoid Tumor, Atypical Teratoid Rhabdoid Tumor
Interventions: alisertib, methotrexate, cisplatin, carboplatin, cyclophosphamide, etoposide, topotecan, vincristine, Surgical resection, Radiation therapy; Drug · Procedure · Radiation
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: Up to 21 Years
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2027
U.S. locations: 9
States / cities: Palo Alto, California • San Diego, California • Aurora, Colorado + 6 more

Conditions: Esophageal Stenosis, Anastomotic Stenosis
Interventions: Mitomycin C, Control; Drug · Other
Lead sponsor: Fox Chase Cancer Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Prostate Cancer, Localized Prostate Carcinoma
Interventions: Leuprolide, Degarelix, Relugolix, Triptorelin, Bicalutamide, 18-F Flotufolastat PSMA PET, Radical prostatectomy; Drug · Diagnostic Test · Procedure
Lead sponsor: Baptist Health South Florida; Other
Eligibility: 18 Years and older · Male only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Postdural Puncture Headache
Interventions: Morphine, Sterile normal saline; Drug
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 4
States / cities: Newark, New Jersey • New York, New York

Conditions: Thrombocytopenia
Interventions: Tranexamic Acid, Placebo; Drug
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 330 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 3
States / cities: Chapel Hill, North Carolina • Pittsburgh, Pennsylvania • Seattle, Washington

Conditions: Wrinkles in Decolletage, Pigmentation, Décolleté Wrinkles
Interventions: KB304, 0.9% Normal Saline (NS); Biological · Drug
Lead sponsor: Krystal Biotech, Inc.; Industry
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Newport Beach, California

Conditions: Strabismus
Interventions: subtenons anesthetic - preservative-free bupivacaine 0.75%, topical anesthetic - 0.5 cc of lidocaine 3.5% ophthalmic gel, topical control - 0.5 cc of Hypromellose 0.3% gel, subtenons control - 0.5 cc of Normal Saline; Drug
Lead sponsor: Duke University; Other
Eligibility: 1 Year to 7 Years
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2013
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Knee Osteoarthritis
Interventions: Placebo, Dextrose prolotherapy (DPT); Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 40 Years to 80 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Avian Influenza, Influenza Immunisation
Interventions: A/H7N9, MF59, Phosphate Buffered Saline (PBS) diluent; Biological · Drug · Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 64 Years
Enrollment: 372 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 7
States / cities: Birmingham, Alabama • St Louis, Missouri • Cincinnati, Ohio + 4 more

Conditions: Shock
Interventions: Ascorbic Acid, Ringers Lactate or Normal Saline; Drug · Other
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Schizotypal Personality Disorder, SPD
Interventions: DAR 0-100A, Placebo; Drug
Lead sponsor: Antonia New; Other
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Cardiac Arrest
Interventions: amiodarone, Lidocaine, Normal saline; Drug · Other
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 3,024 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 7
States / cities: Birmingham, Alabama • San Diego, California • Portland, Oregon + 4 more

Search by objective public record fields.

Deferoxamine to Prevent Delayed Cerebral Ischemia After Subarachnoid Hemorrhage

Botulinum Toxin Injection With Prostate Brachytherapy

Biocellular-Cellular Regenerative Treatment Scaring Alopecia and Alopecia Areata

Low Dose Vasopressin in Traumatic Shock

N-Acetylcysteine to Prevent Radiocontrast Nephropathy in Emergency Department Patients

Heparin Versus Normal Saline in Peripherally Inserted Central Catheter Lines

Trial of Mesna to Prevent Doxorubicin-induced Plasma Protein Oxidation and Tumor Necrosis Factor Alpha (TNF-α) Release

Phase I/II Study of Mitoxantrone, Etoposide and Gemtuzumab Ozogamicin for Acute Myeloid Leukemia

Use of Autologous Platelet-Rich Plasma to Treat Hypertrophic Burn Scars

Ketamine For Acute Treatment of Pain in Emergency Department

A Pilot Study Comparing Anti-Inflammatory Effects Of TXA Versus EACA In Pediatric Congenital Heart Surgery

Optical Imaging Measurement of Intravascular Solution Efficacy Trial

Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors

Efficacy of Topical Mitomycin C for Complex Benign Esophageal Anastomotic Strictures

Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA PET/CT

2 Dose Neuraxial Morphine for Prevention of PDPH

American Trial Using Tranexamic Acid in Thrombocytopenia

A Study Assessing KB304 for the Treatment of Wrinkles in Women

Postoperative Subtenons Anesthesia for Postoperative Pain in Pediatric Strabismus Surgery

Intraarticular Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis

Safety/Efficacy Study of Seqirus A/H7N9 IIV With or Without MF59(R) Adjuvant to Prevent Avian Influenza

High Dose Vitamin C in the Critically Ill Patient

A D1 Agonist For Working Memory

Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Tachycardia