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Showing 1–24 of 217 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Normal Sleep Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms of Endothelial Cell Dysfunction in Sleep Apnea

NCT00859950
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hypoxemia
Interventions
Continuous Positive Airway Pressure (CPAP)
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
21 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Menopausal Sleep Fragmentation and Body Fat Gain

NCT03047330
View directory record Official record
Conditions
Menopause
Interventions
Estradiol withdrawal, Fragmented sleep
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Phase 3 Interventional Results available

Brain Function in Premenopausal Women Receiving Tamoxifen With or Without Ovarian Function Suppression for Early-Stage Breast Cancer on Clinical Trial IBCSG 24-02

NCT00659373
View directory record Official record
Conditions
Breast Cancer, Fatigue, Sleep Disorders
Interventions
Tamoxifen, triptorelin, Exemestane
Drug
Lead sponsor
ETOP IBCSG Partners Foundation
Network
Eligibility
Up to 120 Years · Female only
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
13
States / cities
Sacramento, California • Fort Collins, Colorado • Norwalk, Connecticut + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2016 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Not applicable Interventional

A Pilot Study to Examine Sleep and Fatigue in Pediatric Brain Tumor Patients Hospitalized for High Dose Chemotherapy

NCT00666614
View directory record Official record
Conditions
Sleep, Fatigue
Interventions
Sleep Environment Intervention, Normal Hospital Environment
Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
4 Years to 21 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 18, 2019 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Peanut Butter on Sleep Quality and Daily Energy Levels in Fire Fighters

NCT06364202
View directory record Official record
Conditions
Sleep, Body Composition, Blood Pressure, Physical Activity
Interventions
Peanut Butter
Dietary Supplement
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 14, 2024 · Synced Sep 5, 2026, 2:42 PM EDT
Recruiting Not applicable Interventional

Restorative Early Sleep Treatment After the Emergency Department

NCT07121270
View directory record Official record
Conditions
Insomnia, Nightmares Associated With Trauma and Stress, Nightmares, PTSD - Post Traumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy for Insomnia, Cognitive Behavioral Therapy for Insomnia and Nightmares, Sleep Education, Sleep Education enhanced with Nightmare Education
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Sep 5, 2026, 2:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Atlas of Retinal Imaging in Alzheimer's Study

NCT03862222
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Mild Dementia, Aging, Cognitive Change
Interventions
Retinal Imaging, Pupillometry, Contrast Sensitivity, Neuropsychological Evaluation, APOE genotyping, blood draw, Gait Assessment, Actigraphy
Other · Diagnostic Test · Genetic
Lead sponsor
University of Rhode Island
Other
Eligibility
55 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
4
States / cities
Clearwater, Florida • St. Petersburg, Florida • Kingston, Rhode Island + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 5, 2026, 2:42 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Age-Related Changes in Sleep-Dependent Emotional Memory

NCT04141722
View directory record Official record
Conditions
Sleep, Age, Emotional Valence
Interventions
Overnight sleep, Wake
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 27, 2019 · Synced Sep 5, 2026, 2:42 PM EDT
Active, not recruiting Not applicable Interventional

Addressing Financial and Social Needs Among Patients With Cancer

NCT06430840
View directory record Official record
Conditions
Cancer, Financial Hardship
Interventions
CostCOM (Cost Communication, Financial navigation and counseling), Provision of local and national resources to address financial and social needs, Financial Education, Usual care, Screening for financial and social needs
Behavioral · Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
6
States / cities
Costa Mesa, California • Fountain Valley, California • Irvine, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 5, 2026, 2:42 PM EDT
Terminated Phase 4 Interventional Results available

Palatal Implants in Combination With Continuous Positive Airway Pressure to Treat Obstructive Sleep Apnea

NCT00730041
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Pillar Palatal Implant System, Sham system
Device
Lead sponsor
Medtronic Xomed, Inc.
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
7
States / cities
Little Rock, Arkansas • Berkeley, California • Denver, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2010 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Snooze Control: Sleep Duration & Glucose Metabolism

NCT02583750
View directory record Official record
Conditions
Glucose Metabolism Disorders
Interventions
OGTT after deprived sleep first, OGTT after sufficient sleep first
Behavioral
Lead sponsor
Xuewen Wang
Other
Eligibility
18 Years to 25 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 21, 2015 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Motor Training in PD

NCT02457832
View directory record Official record
Conditions
Parkinson Disease
Interventions
Adapted Tango Dancing, Behavioral Control (BC) Condition
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 70 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 5, 2026, 2:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Heart Rate Changes During Normal Activity, Exercise, and Sleep in Normal Healthy Subjects With and Without Epilepsy

NCT01202682
View directory record Official record
Conditions
Healthy, Exercise
Interventions
Not listed
Lead sponsor
Cyberonics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 23, 2011 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Timing and Energy Balance

NCT01866280
View directory record Official record
Conditions
Sleep, Meals
Interventions
Normal sleep, Normal meals, Late sleep, Late meals
Behavioral
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
20 Years to 45 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2015 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Timing on Energy Intake and Energy Expenditure

NCT05096585
View directory record Official record
Conditions
Obesity
Interventions
Delayed bedtime sleep restriction, Early wake sleep restriction
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 45 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 9, 2023 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Repeated Challenge of Insufficient Sleep: Endothelial Effects

NCT01523535
View directory record Official record
Conditions
Repeated Short Sleep Schedule
Interventions
repeated cycles of short sleep
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
25 Years to 55 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2020 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Not applicable Interventional

Sleep, Blood Pressure and Vascular Health

NCT04017039
View directory record Official record
Conditions
Blood Pressure, Sleep
Interventions
Targeted Sleep Intervention
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
45 Years to 65 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Sleep Restriction on Adipose Tissue and Skeletal Muscle Insulin Sensitivity

NCT04286451
View directory record Official record
Conditions
Sleep Disturbance, Postmenopausal Symptoms, Insulin Sensitivity, Cardiovascular Risk Factor
Interventions
Sleep Restriction, Habitual Sleep
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 15, 2022 · Synced Sep 5, 2026, 2:42 PM EDT
Enrolling by invitation Phase 4 Interventional Accepts healthy volunteers

MIBG in Aging and Neurologic Disorders

NCT05514106
View directory record Official record
Conditions
Lewy Body Disease, Dementia, Parkinsonism, Mild Cognitive Impairment, REM Sleep Behavior Disorder
Interventions
meta-iodobenzylguanidine (MIBG) (123I), 123I-MIBG scintigraphy
Drug · Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Not applicable Interventional

A Comparison of Two Different Methods of Physical Therapy to Treat Acute and Subacute Low Back Pain

NCT02060617
View directory record Official record
Conditions
Low Back Pain
Interventions
Patient Education, Manual therapy of the thoracolumbosacral spine and hips, Motor control exercises, Treatment-Based Classification intervention
Behavioral · Procedure
Lead sponsor
Hendricks Regional Health
Other
Eligibility
18 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Plainfield, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 28, 2016 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Phase 2 Interventional

ROAR-DIGAP: A Widely Inclusive, Largely Virtual Pilot Trial Utilizing DIGAP (Deep Integrated Genomics Analysis Platform) To Personalize Treatments

NCT06429059
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis ALS
Interventions
Astaxanthin, Protandim, Melatonin, MitoQ
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Sep 5, 2026, 2:42 PM EDT
Completed Not applicable Interventional

The Influence of Cardiorespiratory Fitness on Firefighter Cardiovascular Health Under Exercise Conditions

NCT04514354
View directory record Official record
Conditions
Cardiovascular Diseases, Post-Exercise Hypotension
Interventions
GEST
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Sep 5, 2026, 2:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Sleep Restriction on Blood Pressure Reactivity

NCT07489417
View directory record Official record
Conditions
Sleep, Blood Pressure
Interventions
Sleep Restriction
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 45 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 5, 2026, 2:42 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Adaptions and Resiliency to Multi-Stressor OpeRations

NCT06455969
View directory record Official record
Conditions
Musculoskeletal Injury, Hypogonadism, Hormonal Contraception
Interventions
Goserelin 3.6 MG, Multi-Stressor Training, Testosterone gel (AndroGel 5g), Testosterone gel (AndroGel 1.25g)
Drug · Other
Lead sponsor
Bradley Nindl
Other
Eligibility
18 Years to 40 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 5, 2026, 2:42 PM EDT