Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 9, 2026, 6:28 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2377–2400 of 2,691 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Normal saline solution Clear all

Conditions: Arthroplasty, Replacement, Knee, Total Knee Arthroplasty
Interventions: Lidocaine IV, Saline IV; Drug
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Pain
Interventions: Hypertonic Saline, Normal Saline; Drug · Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 4 Years to 17 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: San Diego, California

Conditions: Cytomegalovirus Infection
Interventions: mRNA-1647, Placebo; Biological
Lead sponsor: ModernaTX, Inc.; Industry
Eligibility: 16 Years to 40 Years · Female only
Enrollment: 7,454 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 181
States / cities: Birmingham, Alabama • Dothan, Alabama • Guntersville, Alabama + 141 more

Conditions: Pain
Interventions: Ropivacine and Chloroprocaine mixture, Ropivacaine only; Drug
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Intracranial Embolism, Cerebral Thromboembolism, Carotid Stenosis
Interventions: ARC1779 Injection, Placebo (normal saline); Drug
Lead sponsor: Archemix Corp.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 2
States / cities: Hackensack, New Jersey • Houston, Texas

Conditions: Cervical Dystonia
Interventions: botulinum toxin type A, botulinum toxin type A Formulation 2, Normal Saline; Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 242 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Surgical Recovery, Pain, Postoperative
Interventions: N-acetyl cysteine, Normal Saline; Drug · Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Stanford, California

Conditions: Severe Sepsis or Septic Shock
Interventions: Calcitriol, Placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Friedreich Ataxia
Interventions: plethysmography; Diagnostic Test
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 79 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Hypoglycemia
Interventions: Exendin (9-39), Placebo; Drug · Other
Lead sponsor: Tracey McLaughlin; Other
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2014
U.S. locations: 1
States / cities: Stanford, California

Conditions: Squamous Cell Carcinoma in Situ
Interventions: STP705, Placebo Saline; Drug · Other
Lead sponsor: Sirnaomics; Industry
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 7
States / cities: Scottsdale, Arizona • Aventura, Florida • West Palm Beach, Florida + 4 more

Conditions: Infant, Newborn, Diseases, Cardiovascular Insufficiency
Interventions: Hydrocortisone, Placebo; Drug
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: 34 Weeks and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 18
States / cities: Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 14 more

Conditions: Wound, Ulcer, Burns
Interventions: Negative pressure wound therapy coupled with instillation, Standard Negative Pressure Wound Therapy; Device
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Paroxysmal Atrial Fibrillation, Indications for CABG
Interventions: botulinum toxin injection, 0.9% normal saline injection, Implantable loop recorder; Biological · Device
Lead sponsor: Meshalkin Research Institute of Pathology of Circulation; Network
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: New York, New York

Conditions: Kidney Transplant Failure and Rejection
Interventions: Tacrolimus (TAC), Sirolimus, Alemtuzumab, Mycophenolate mofetil (MMF); Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Mastectomy, Nerve Block, Analgesia, Postoperative
Interventions: Pectoralis block, Normal saline injection, Ropivacaine Injection; Procedure · Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Scorpion Sting Envenomation
Interventions: Antivenin Centruroides (scorpion) equine immune F(ab)2, Placebo; Biological · Other
Lead sponsor: Instituto Bioclon S.A. de C.V.; Industry
Eligibility: 6 Months to 18 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 2
States / cities: Tucson, Arizona

Conditions: Familial Hypercholesterolemia - Heterozygous
Interventions: Inclisiran, Placebo; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 6 Years to 11 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 9
States / cities: San Francisco, California • Washington D.C., District of Columbia • Boca Raton, Florida + 4 more

Conditions: Prediabetes, Obesity
Interventions: Exenatide, Saxagliptin, Exenatide extended-release (ER), Placebo; Drug · Other
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 30 Years to 70 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Anorexia Nervosa
Interventions: Isoproterenol, placebo; Drug · Other
Lead sponsor: Laureate Institute for Brain Research, Inc.; Other
Eligibility: 18 Years to 40 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: Tulsa, Oklahoma

Conditions: Opioid Dependence, Pain, Addiction
Interventions: Placebo, Hydromorphone, Buprenorphine; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Nausea
Interventions: Inhaled isopropyl alcohol, Oral ondansetron, Inhaled normal saline, Oral placebo; Drug
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 122 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Incisional Pain
Interventions: TAP Catheter and Infusion of Study Solution; Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: San Diego, California

Conditions: Post-traumatic Stress Disorder
Interventions: Stellate Ganglion Block, Sham Stellate Ganglion Block; Procedure
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 410 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 6
States / cities: Long Beach, California • Tampa, Florida • Minneapolis, Minnesota + 3 more

Search by objective public record fields.

Systemic Lidocaine Versus Ultrasound-guided Adductor Canal Block for Patients Undergoing Total Knee Arthroplasty

Hypertonic Saline as Therapy for Pediatric Concussion

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Healthy Participants 16 to 40 Years of Age

Trial Comparing the Onset and Duration of Ultrasound Guided Supraclavicular Nerve Blocks Using Ropivacaine Versus Ropivacaine-Chloroprocaine Mixture

Effect of ARC1779 on Cerebral Microembolism in Patients Undergoing Carotid Endarterectomy

Study to Evaluate Safety, Efficacy of Botulinum Toxin Type A in Patients With Cervical Dystonia

Oxidative Stress and Surgical Recovery

Randomized Controlled Trial of Calcitriol vs. Placebo Among Critically-ill Patients With Sepsis

Coronary Artery Disease in Patients With Friedreich's Ataxia

Role of GLP-1 in Hyperinsulinemic Hypoglycemia Post-bariatric Surgery

A Study to Evaluate Safety, Efficacy of Intralesional Injection of STP705 in Patients With isSCC

Hydrocortisone for Term Hypotension

Coupling Negative Pressure Wound Therapy With Instillation

Botulinum Toxin Injection in Epicardial Fat Pads To Treat Atrial Fibrillation After Cardiac Surgery

A Trial of Two Steroid-Free Approaches Toward Mycophenolate Mofetil-Based Monotherapy Immunosuppression

Effect of Pectoralis Block on Analgesia After Simple Mastectomy

Double-Blind, Alacramyn® vs. Placebo in Pediatric Patients

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Effects of Antidiabetic Medications on the Postprandial State in Prediabetes

Augmented Interoceptive Exposure Training in Anorexia Nervosa

Study of the Treatment of Experimental Pain in Opioid Dependent Persons on Methadone or Buprenorphine Maintenance

Isopropyl Alcohol vs Ondansetron for Nausea in the Emergency Department

Continuous Transversus Abdominis Plane Nerve Block for Postoperative Analgesia

Stellate Ganglion Block for PTSD