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ClinicalTrials.gov public records Last synced Nov 9, 2026, 7:15 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2401–2424 of 2,691 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Normal saline solution Clear all

Conditions: Healthy
Interventions: Recombinant Human Prolactin; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Osteoarthritis, Knee
Interventions: Bone Marrow Derived MSCs, Corticosteroid, Bone Marrow Aspirate; Biological · Drug · Device
Lead sponsor: Next Generation Regenerative Medicine LLC; Network
Eligibility: 18 Years to 80 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 3
States / cities: Chesterfield, Missouri • Steubenville, Ohio • Salt Lake City, Utah

Conditions: Cytomegalovirus Infection
Interventions: mRNA-1647, Placebo; Biological · Other
Lead sponsor: ModernaTX, Inc.; Industry
Eligibility: 18 Years to 40 Years
Enrollment: 315 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 9
States / cities: Sacramento, California • Peoria, Illinois • Lenexa, Kansas + 5 more

Conditions: Neuroblastoma, Pheochromocytoma, Paraganglioma
Interventions: I-131 MIBG; Radiation
Lead sponsor: Jubilant DraxImage Inc.; Industry
Eligibility: 12 Months and older
U.S. locations: 19
States / cities: Los Angeles, California • Aurora, Colorado • Atlanta, Georgia + 16 more

Conditions: Hip Fractures, Anesthesia, Spinal, Anesthesia, General, Neuromuscular Blockade
Interventions: Rocuronium, Sugammadex, Normal saline; Drug
Lead sponsor: Loyola University; Other
Eligibility: 55 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: Placebo, sodium nitrite 45 mg, sodium nitrite 60 mg; Drug
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 1,502 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Acute Respiratory Distress Syndrome (ARDS), Acute Lung Injury (ALI)
Interventions: methylprednisolone, Normal Saline (0.9%); Drug
Lead sponsor: University of Tennessee; Other
Eligibility: 1 Month to 18 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Postoperative Complications
Interventions: Normal saline, Lactated Ringer's solution; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 8,616 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Infections
Interventions: Normal saline pressurized irrigation, sub-q gentamicin; Procedure · Drug
Lead sponsor: Dallas VA Medical Center; Federal
Eligibility: 18 Years to 95 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Iron Deficiency
Interventions: Iron-dextran, Saline, Blood Donation, 24-hour PTR; Drug · Procedure
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Opioid Use, Surgical Recovery, Vaginal Hysterectomy, Prolapse Pelvic, Postoperative Pain
Interventions: Bupivacaine-epinephrine, Normal saline; Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Raleigh, North Carolina

Conditions: Healthy
Interventions: 5 mg/N6022, Placebo, 10mg/N6022, 20mg/N6022; Drug
Lead sponsor: Nivalis Therapeutics, Inc.; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Ebola Virus Infection
Interventions: TKM-100802 for Injection, Placebo; Drug
Lead sponsor: Arbutus Biopharma Corporation; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Respiratory Syncytial Virus Infections
Interventions: ALN-RSV01, Normal Saline; Drug
Lead sponsor: Alnylam Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 18
States / cities: Phoenix, Arizona • Los Angeles, California • Denver, Colorado + 13 more

Conditions: Type 2 Diabetes Mellitus, Obesity
Interventions: Roux-en-Y Gastric Bypass (RYGB), Caloric Restriction, Exendin-9,39, Normal Saline; Procedure · Behavioral · Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 20 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Muscle Spasticity
Interventions: Hyaluronidase, Placebo; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Post-operative Cognitive Decline, Post-operative Delirium
Interventions: Aspart insulin, Normal saline, Intranasal mucosal atomizer device; Drug · Device
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 65 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Cystic Fibrosis
Interventions: MRT5005, Normal saline; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 16
States / cities: Birmingham, Alabama • Denver, Colorado • Gainesville, Florida + 13 more

Conditions: Osteoarthritis, Knee, Pain, Knee
Interventions: Resiniferatoxin, Saline; Drug
Lead sponsor: Sorrento Therapeutics, Inc.; Industry
Eligibility: 35 Years to 85 Years
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 4
States / cities: Los Angeles, California • Miami, Florida • Boston, Massachusetts + 1 more

Conditions: Chronic Myelogenous Leukemia
Interventions: Busulfan, Cyclophosphamide, Imatinib Mesylate, Autologous Stem Cell Transplantation; Drug · Procedure
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: Up to 70 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Rhinosinusitis
Interventions: SinuSurf irrigation twice daily, NeilMed Sinus rinse irrigation twice daily; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Hysterectomy, Blood Loss, Surgical
Interventions: Tranexamic Acid, Sodium Chloride; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Posttraumatic Stress Disorder
Interventions: Neuropeptide Y; Drug
Lead sponsor: James Murrough; Other
Eligibility: 18 Years to 60 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Suicidal Ideation
Interventions: Ketamine, Normal Saline; Drug
Lead sponsor: Allen Richert; Other
Eligibility: 18 Years to 64 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Jackson, Mississippi

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The Safety and Efficacy of Recombinant Human Prolactin

Mesenchymal Stem Cell Therapy for Knee Osteoarthritis

Dose-Finding Trial to Evaluate the Safety and Immunogenicity of Cytomegalovirus (CMV) Vaccine mRNA-1647 in Healthy Adults

Expanded Access Protocol Using 131I-MIBG

GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip Fracture

Clinical Trial of Sodium Nitrite for Out of Hospital Cardiac Arrest

Trial of Steroids in Pediatric Acute Lung Injury/ARDS

Saline Versus Lactated Ringer's Solution: The SOLAR Fluid Trial

Effectiveness for Interventions to Minimize Surgical Site Infections

Donor Iron Deficiency Study - Red Blood Cells From Iron-deficient Donors: Recovery and Storage Quality

Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse

A Safety Study Evaluating N6022 in Multiple-Ascending Doses in Healthy Subjects

Safety, Tolerability and Pharmacokinetic First in Human (FIH) Study for Intravenous (IV) TKM-100802

Phase 2b Study of ALN-RSV01 in Lung Transplant Patients Infected With Respiratory Syncytial Virus (RSV)

The Effect of Bariatric Surgery on Metabolism, the Metabolome and Microbiome in Patients With Type 2 Diabetes

Peripheral Modulation of Muscle Stiffness and Spasticity

Cardiac Surgery Neuroprotection Study in Elders

Study to Evaluate the Safety & Tolerability of MRT5005 Administered by Nebulization in Adults With Cystic Fibrosis

Study of Resiniferatoxin for Knee Pain in Moderate to Severe Osteoarthritis

Autologous Transplantation for Chronic Myelogenous Leukemia

SinuSurf vs. Saline Solution in Normal Subjects

IV Tranexamic Acid Prior to Hysterectomy

A Dose Escalation Study of Intranasal Neuropeptide Y in Post Traumatic Stress Disorder (PTSD)

The Effect of Ketamine on the Length of Hospital Stay of Patients Hospitalized With Suicidal Ideation.