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ClinicalTrials.gov public records Last synced Nov 10, 2026, 1:24 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2545–2568 of 2,690 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Normal saline solution Clear all

Conditions: Respiratory Tract Infection
Interventions: RSV Vaccine, Tdap, Placebo; Biological
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 49 Years · Female only
Enrollment: 713 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 16
States / cities: Stockbridge, Georgia • Honolulu, Hawaii • Wichita, Kansas + 12 more

Conditions: Squamous Cell Carcinoma of Hypopharynx, Squamous Cell Carcinoma of Larynx, Squamous Cell Carcinoma of Oropharynx, Squamous Cell Carcinoma of Oral Cavity
Interventions: Scheduled IV Hydration, Clinician Assessment-Based IV Hydration; Other
Lead sponsor: West Virginia University; Other
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 6
States / cities: Bridgeport, West Virginia • Martinsburg, West Virginia • Morgantown, West Virginia + 3 more

Conditions: West Nile Fever
Interventions: ChimeriVax-WN02 vaccine, Placebo; Biological
Lead sponsor: Sanofi Pasteur, a Sanofi Company; Industry
Eligibility: 50 Years and older
Enrollment: 479 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 15
States / cities: Anaheim, California • Colorado Springs, Colorado • South Miami, Florida + 12 more

Conditions: Cardiac Arrest, Return of Spontaneous Circulation
Interventions: Magnesium Sulfate, Saline; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 85 Years
Enrollment: 178 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Palate; Wound
Interventions: Amnion-chorion Membrane, ActCel Cellulose Gauze; Other
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 89 Years
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Cancer, Tumour, Surgery
Interventions: Tranexamic acid (TXA), Normal saline; Drug
Lead sponsor: Sunnybrook Health Sciences Centre; Other
Eligibility: 18 Years and older
Enrollment: 1,386 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2027
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Fractures, Comminuted, Surgical Wound Dehiscence, Necrosis
Interventions: ICG (Indocyanine Green); Drug
Lead sponsor: Louisiana State University Health Sciences Center Shreveport; Other
Eligibility: 18 Years to 65 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Shreveport, Louisiana

Conditions: COVID-19
Interventions: Gimsilumab, Placebo; Drug
Lead sponsor: Kinevant Sciences GmbH; Industry
Eligibility: 18 Years and older
Enrollment: 227 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 33
States / cities: Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 21 more

Conditions: Cellulite
Interventions: Calcium Hydroxyapatite; Drug
Lead sponsor: Kalpna Kay Durairaj, MD, FACS; Other
Eligibility: 21 Years to 50 Years · Female only
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Pasadena, California

Conditions: Obesity
Interventions: BTA, Placebo (normal saline); Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Osteoarthritis, Osteo Arthritis Knee, Osteo Arthritis Shoulders, Osteoarthritis of Multiple Joints, Osteoarthritis, Hip, Osteoarthritis - Ankle/Foot
Interventions: Tissue Stromal Vascular Fraction (tSVF) Arm 1, PRP Concentrate Arm 1, Tissue Stromal Vascular Fraction (tSVF) Arm 2, PRP Concentrate Arm 2, Cellular Stromal Vascular Fraction (cSVF) Arm 2, Cellular Stromal Vascular Fraction (cSVF) Arm 3, Sterile Normal Saline (IV Solution); Procedure · Biological · Drug
Lead sponsor: Healeon Medical Inc; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 2
States / cities: Valencia, California • Stevensville, Montana

Conditions: Ectropion, Skin Neoplasms
Interventions: 5-Fluorouracil, Normal saline; Drug · Other
Lead sponsor: Massachusetts Eye and Ear Infirmary; Other
Eligibility: 18 Years to 89 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Transesophageal Echocardiography Contrast Agents
Interventions: normal saline, human albumin, human albumin and propofol; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Premature Ejaculation
Interventions: OnabotulinumtoxinA, Normal Saline; Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 50 Years · Male only
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 6
States / cities: San Diego, California • Torrance, California • Middlebury, Connecticut + 3 more

Conditions: Pain
Interventions: Bipivacaine 0.5% with epinephrine, Normal Saline; Drug
Lead sponsor: Souza, Amanda, M.D.; Individual
Eligibility: 21 Years to 65 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Farmington Hills, Michigan

Conditions: Marburg Hemorrhagic Fever
Interventions: AVI-6003, Placebo; Drug
Lead sponsor: Sarepta Therapeutics, Inc.; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011
U.S. locations: 1
States / cities: Cypress, California

Conditions: Cervical Cancer
Interventions: Pembrolizumab, Paclitaxel, Cisplatin, Carboplatin, Bevacizumab, Placebo to pembrolizumab; Biological · Drug
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 617 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 20
States / cities: Anchorage, Alaska • Phoenix, Arizona • Orange, California + 15 more

Conditions: Clostridium Difficile Infection (CDI)
Interventions: RBX2660, Placebo, Open label RBX2660 (only for confirmed CDI recurrence); Drug
Lead sponsor: Rebiotix Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 320 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 60
States / cities: Athens, Alabama • Dothan, Alabama • Phoenix, Arizona + 54 more

Conditions: Type 2 Diabetes
Interventions: GIP, Modified GIP, Normal Saline; Drug
Lead sponsor: National Institute on Aging (NIA); NIH
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Urinary Retention
Interventions: Retained fluid, Emptied fluid; Procedure
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years and older · Female only
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Acute Bronchiolitis
Interventions: 3% Hypertonic Saline, 0.9 % normal saline; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 2 Months to 12 Months
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Pain
Interventions: Bupivacaine, Placebo; Drug
Lead sponsor: Children's Hospitals and Clinics of Minnesota; Other
Eligibility: Up to 17 Years
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Cancer-related Fatigue
Interventions: Thyrotropin releasing hormone (TRH), Placebo; Drug
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Cancer
Interventions: anti-thymocyte globulin, rituximab, clofarabine, stem cell transplantation; Biological · Drug · Procedure
Lead sponsor: Masonic Cancer Center, University of Minnesota; Other
Eligibility: Not listed
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2015
U.S. locations: 1
States / cities: Minneapolis, Minnesota

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A STUDY OF A RSV VACCINE WHEN GIVEN TOGETHER WITH TDAP IN HEALTHY NONPREGNANT WOMEN AGED BETWEEN 18 TO 49 YEARS

Scheduled IV Fluids in the Supportive Management of Patients Undergoing Chemo-radiotherapy for Head and Neck Cancer

Safety and Immunogenicity Study of ChimeriVax West Nile Vaccine in Healthy Adults

Post-CA Neuroprotection With Magnesium

Palatal Donor Site Wound Healing Following Periodontal Plastic Surgery Using Amnion-Chorion Membrane

The HeLiX (Hemorrhage During Liver Resection: traneXamic Acid) Trial

Application of Indocyanine Green Angiography for Closed Operative Calcaneus Fractures

A Study to Assess the Efficacy and Safety of Gimsilumab in Subjects With Lung Injury or Acute Respiratory Distress Syndrome Secondary to COVID-19 (BREATHE)

Effects of Calcium Hydroxylapatite on Cellulite Dimples in the Buttocks

Effects of Gastric Antral Botulinum Toxin Injections in Obese Subjects

Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis

5-fluorouracil Versus Placebo in Periocular Full Thickness Skin Grafts

Agitated Saline, Albumin, or Propofol-albumin Mixture for Enhanced Contrast in TEE Examinations

A Safety and Efficacy Study of OnabotulinumtoxinA in Premature Ejaculation

Bupivacaine Injections Into Uterosacral Ligaments During Robotic Assisted Total Hysterectomies

Safety Study of Single Administration Post-exposure Prophylaxis Treatment for Marburg Virus

Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826)

Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCHCD3)

GIP: Glucose-dependent Insulinotropic Peptide

Post Hysterectomy Benefits of Retained Cystoscopy Fluid

Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis

Parasternal Nerve Block Using Bupivacaine for Postoperative Analgesia in Children Undergoing Cardiac Surgery

Evaluation of Synthetic Thyrotropin Releasing Hormone (TRH) as a Treatment for Cancer-related Fatigue

Antithymocyte Globulin, Clofarabine, and Rituximab in Treating Patients After an Unsuccessful Stem Cell Transplant