Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 6, 2026, 1:52 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1969–1992 of 2,691 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Normal saline solution Clear all

Conditions: Pain
Interventions: Ketamine, Placebo; Drug
Lead sponsor: The Brooklyn Hospital Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Severe Sepsis, Septic Shock
Interventions: NICOM/FloTrac, Crystalloid Fluid Challenge; Device · Other
Lead sponsor: Santa Barbara Cottage Hospital; Other
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Santa Barbara, California

Conditions: Wound Infection Rate
Interventions: wound irrigation with study fluid; Procedure
Lead sponsor: Stanford University; Other
Eligibility: 12 Months and older
Enrollment: 660 participants
Timeline: 1994 – 1996
U.S. locations: 1
States / cities: Stanford, California

Conditions: Acute Pain, Regional Anesthesia Morbidity
Interventions: ropivacaine, bupivacaine, Sham Adductor Canal Catheter, Adductor Canal Catheter; Drug · Device
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 40 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Melanoma
Interventions: Intismeran autogene, Pembrolizumab, Placebo; Biological · Other
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Eligibility: 18 Years and older
Enrollment: 1,089 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2030
U.S. locations: 34
States / cities: Springdale, Arkansas • Los Angeles, California • San Francisco, California + 27 more

Conditions: Lassa Fever
Interventions: LASSARAB+ aPHAD-SEat 700rU, HDCV Comparator, Normal Saline Placebo, LASSARAB+ aPHAD-SEat 1400rU; Biological · Other
Lead sponsor: Wilbur Chen, MD, MS; Other
Eligibility: 18 Years to 50 Years
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Muscle-Invasive Bladder Carcinoma, Bladder Cancer
Interventions: CG0070, Nivolumab; Drug
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Post-Traumatic Stress Disorders, Major Depressive Disorder
Interventions: Ketamine, Normal Saline; Drug · Other
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 75 Years
Enrollment: 67 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Hypogammaglobulinemia, Bacterial Infections, B-cell Chronic Lymphocytic Leukemia, Multiple Myleoma, Non-Hodgkin Lymphoma
Interventions: Xembify, Placebo; Drug
Lead sponsor: Grifols Therapeutics LLC; Industry
Eligibility: 18 Years and older
Enrollment: 386 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2029
U.S. locations: 9
States / cities: Bullhead City, Arizona • Huntington Park, California • St. Petersburg, Florida + 6 more

Conditions: Atrophic Acne Scar
Interventions: Normal Saline, Artefill; Drug · Device
Lead sponsor: Suneva Medical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 175 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 10
States / cities: Beverly Hills, California • Los Angeles, California • San Diego, California + 7 more

Conditions: Pelvic Floor Disorders
Interventions: Bladder scan post void residual, Straight catheter post void residual, Back fill voiding trial; Device · Procedure
Lead sponsor: Tufts Medical Center; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Preeclampsia
Interventions: Oxytocin, Placebo; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 13 Years to 45 Years · Female only
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Mastectomy, Breast Cancer
Interventions: Liposomal bupivacaine, Standard bupivacaine, Placebo; Drug · Other
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Warts
Interventions: Human Papillomavirus 9-valent Vaccine, Recombinant, Normal Saline; Biological · Other
Lead sponsor: Western Institute for Veterans Research; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Salt Lake City, Utah

Conditions: Head and Neck Cancer
Interventions: ZD 1839 500mg; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2018
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Antibody-mediated Rejection, NMO Spectrum Disorder, TTP, CIDP
Interventions: Not listed
Lead sponsor: Charles M Knudson; Other
Eligibility: 12 Years to 99 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2040
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Familial Hypercholesterolemia - Homozygous
Interventions: Inclisiran, Placebo; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 2 Years to 11 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 4
States / cities: San Francisco, California • Washington D.C., District of Columbia • St Louis, Missouri + 1 more

Conditions: Pregnancy
Interventions: Iloprost, normal saline; Drug · Other
Lead sponsor: Fertility Specialists of Houston; Other
Eligibility: 20 Years to 39 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Epstein-Barr Virus Infection, Infectious Mononucleosis, Herpesvirus
Interventions: Matrix-M1 Adjuvant, EBV gp350-Ferritin Vaccine, Placebo Comparator; Drug · Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 25 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Bethesda, Maryland • Minneapolis, Minnesota

Conditions: Osteoarthritis, Pain
Interventions: Exparel, Femoral Nerve Block Bupivacaine, Toradol, Morphine Sulfate; Drug
Lead sponsor: The New England Baptist Hospital; Other
Eligibility: 18 Years to 73 Years
Enrollment: 312 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Coagulation; Intravascular, Rotational Thromboelastometry, Fibrinolysis; Hemorrhage, Tranexamic Acid, Total Hip Arthroplasty
Interventions: Tranexamic Acid, Placebo; Drug
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Kidney Diseases
Interventions: YSPSL, placebo; Drug
Lead sponsor: Y's Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 15
States / cities: Los Angeles, California • San Francisco, California • Denver, Colorado + 11 more

Conditions: Post-Traumatic Headache
Interventions: Bupivacaine bilateral greater occipital nerve block; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Post Operative Pain, Nausea and Vomiting, Postoperative, Opioid Use
Interventions: bilateral superficial cervical plexus blocks and local wound infiltration, placebo injection and local wound infiltration; Procedure
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years to 99 Years
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Sacramento, California

Search by objective public record fields.

Ketamine For Acute Treatment of Pain in Emergency Department

Monitoring Devices in Prediction of Fluid Responsiveness in Severe Sepsis and Septic Shock

Tap Water Versus Normal Saline for Wound Irrigation

Adductor Canal Catheter vs Local Infiltration of Analgesia for Total Knee Arthroplasty

A Clinical Study of Intismeran Autogene (V940) Plus Pembrolizumab in People With High-Risk Melanoma (V940-001)

DMID 23-0015; Lassa Fever CVD 1000

Study of CG0070 Combined With Nivolumab in Cisplatin Ineligible Patients With MIBC

Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

Use of Artefill® for Moderate to Severe Atrophic Acne Scar Correction

Accuracy of Bladder Scanners in Post-operative Voiding Trials

Postpartum Hemorrhage Prevention in Patients With Preeclampsia (PHP3 Study)

Post-Mastectomy Analgesia Using Exparel (Liposomal) Versus Standard Bupivacaine or Placebo

Human Papillomavirus (HPV) Vaccination vs. Placebo for the Treatment of Refractory Cutaneous Warts

Trial of Induction Chemotherapy With Carboplatin and Paclitaxel, Followed by Concurrent Chemotherapy/Radiation Therapy With ZD1839 (IRESSA), 5-FU, Hydroxyurea, and Twice-Daily Radiation, Followed by Adjuvant ZD1839 Monotherapy in Patients With Locally Advanced Head & Neck Cancer

Biorepository and Registry for Plasma Exchange Patients

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

Enhanced Assisted Reproductive Technology Pregnancy Rate by Prostacyclin Analog (Iloprost)

Trial Evaluating the Immunogenicity and Safety of an Adjuvanted Epstein-Barr Virus (EBV) Glycoprotein 350 Vaccine in EBV-seronegative Persons

Femoral Nerve Block Compared to Exparel in Total Knee Replacement

The Effect of Tranexamic Acid on Blood Coagulation in Total Hip Arthroplasty Surgery

YSPSL for Prevention of Delayed Graft Function Part B

Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 2

ENDOblock: Bilateral Superficial Cervical Blocks With Local Wound Infiltration in Thyroid Surgery