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ClinicalTrials.gov public records Last synced Nov 9, 2026, 5:20 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2065–2088 of 2,691 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Normal saline solution Clear all

Conditions: Chronic Pain, Depression
Interventions: Ketamine, Normal saline; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Stanford, California

Conditions: Healthy Participants
Interventions: Combination [RSVpreF+BNTb162b2], Bivalent BNT162b2 (original/Omi BA.4/BA.5), RSVpreF, QIV, Normal Saline Placebo; Biological
Lead sponsor: Pfizer; Industry
Eligibility: 65 Years and older
Enrollment: 1,142 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 37
States / cities: Dublin, California • Huntington Beach, California • Lake Forest, California + 26 more

Conditions: Surgical Site Infection
Interventions: Povidone-Iodine, Normal Saline; Drug · Other
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 3 Years to 18 Years
Enrollment: 173 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Kansas City, Missouri • Philadelphia, Pennsylvania

Conditions: Cardiac Surgery-CABG, Cardiac Valve Replacement
Interventions: Epogen, Normal Saline; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 64 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Achalasia, Dysphagia
Interventions: Submucosal endoscopic myotomy with mucosal flap technique, Submucosal Endoscopic Mucosal Flap (SEMF) technique; Procedure
Lead sponsor: Winthrop University Hospital; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Mineola, New York

Conditions: Post-Cesarean Pain, Cesarean Section Complications
Interventions: Dexamethasone, placebo; Drug · Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Hypertension
Interventions: clevidipine; Drug
Lead sponsor: The Medicines Company; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 2
States / cities: Boston, Massachusetts • Philadelphia, Pennsylvania

Conditions: Corneal Abrasion
Interventions: Ophthalmic Tetracaine, Normal Saline; Drug · Other
Lead sponsor: New York Presbyterian Brooklyn Methodist Hospital; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Nail Psoriasis, Nail Diseases
Interventions: Placebos, Triamcinolone Acetonide 2.5 mg/mL, Triamcinolone Acetonide 5.0 mg/mL, Triamcinolone Acetonide 7.5 mg/mL, Triamcinolone Acetonide 10 mg/mL; Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Rift Valley Fever
Interventions: IDB-011 dose level 1, IDB-011 dose level 2, IDB-011 dose level 3, IDB-011 dose level 4, IDB-011 dose level 5, Placebo; Drug · Other
Lead sponsor: IDBiologics, Inc.; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Cypress, California

Conditions: Fever, Critical Illness
Interventions: Acetaminophen, Placebo; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 2
States / cities: San Francisco, California

Conditions: Androgenetic Alopecia
Interventions: NTAP; Device
Lead sponsor: Dr. Peter C. Friedman; Industry
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: New City, New York

Conditions: Sepsis, Systemic Inflammatory Response Syndrome
Interventions: Automated Pulse Pressure Variation; Device
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: Up to 17 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Premature Ejaculation
Interventions: OnabotulinumtoxinA, Normal Saline; Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years to 50 Years · Male only
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 6
States / cities: San Diego, California • Torrance, California • Middlebury, Connecticut + 3 more

Conditions: Lateral Canthus Rhytides, Crow's Feet Lines
Interventions: onabotulinumtoxinA, normal saline; Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 446 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Newport Beach, California

Conditions: Facial Rhytides, Glabellar Rhytides
Interventions: OnabotulinumtoxinA, Normal Saline; Biological · Drug
Lead sponsor: Allergan; Industry
Eligibility: 18 Years and older
Enrollment: 787 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 10
States / cities: Little Rock, Arkansas • Los Angeles, California • Newport Beach, California + 6 more

Conditions: Breast Cancer Female
Interventions: Bupivacaine Hydrochloride, Placebo Drug, Pulsed Electromagnetic Field (PEMF) Device, Placebo Device, Ropivacaine Hydrochloride; Drug · Other · Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Postoperative Pain
Interventions: Dexamethasone, Placebo; Drug
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Androgenetic Alopecia, Alopecia
Interventions: Platelet Rich Plasma, Normal saline; Device · Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Thyroidectomy, Nerve Monitoring
Interventions: Lidocaine, Placebo; Drug
Lead sponsor: Bronx-Lebanon Hospital Center Health Care System; Other
Eligibility: 18 Years to 85 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Aging
Interventions: Esmolol infusion, Saline infusion, Pre exercise baseline, Isometric handgrip exercise, Semi-recumbent cycling; Drug · Other
Lead sponsor: David N. Proctor, PhD; Other
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Aqueous Deficient Dry Eye, Meibomium Gland Dysfunction
Interventions: Subjective Questionnaire, Measurement with wavefront sensor (right eye, then left eye), Instill Saline Drop; Behavioral · Procedure · Drug
Lead sponsor: University of Rochester; Other
Eligibility: 20 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Rochester, New York

Conditions: This Study Will Evaluate Whether TXA Reduces Pain
Interventions: Tranexamic acid, placebo; Drug · Other
Lead sponsor: St. Louis Joint Replacement Institute; Other
Eligibility: Not listed
Enrollment: 165 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Bridgeton, Missouri

Conditions: Back Pain, Chronic Low Back Pain, Internal Disc Disruption, Degenerative Disc Disease
Interventions: BIOSTAT BIOLOGX, Saline; Biological · Drug
Lead sponsor: Spinal Restoration, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 20
States / cities: Birmingham, Alabama • Phoenix, Arizona • Chula Vista, California + 17 more

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Propofol-Enhanced Assessment of Ketamine for Chronic Pain and Depression

A Study to Learn About Two or More Vaccines That Are Put Together as One Shot Against Infectious Lung Illnesses, Including COVID-19 and Respiratory Syncytial Virus (RSV).

Bacterial Contamination: Iodine vs Saline Irrigation in Pediatric Spine Surgery

EPOgen and Restrictive Transfusions in Patients Undergoing Cardiac Surgery (EPORT)

Efficacy & Safety of Submucosal Endoscopic Myotomy With Mucosal Flap (SEMF) in the Treatment of Patients With Achalasia

Postoperative Dexamethasone on Post-Cesarean Pain

Clevidipine Bolus Administration in the Treatment of Hypertensive Patients Undergoing Cardiac Surgery (SPRINT)

Treatment of Corneal Abrasions With Topical Tetracaine

Benefit of Placebo and Different Concentrations of Triamcinolone Acetonide in Nail Psoriasis

Study to Evaluate Safety, Tolerability and Pharmacokinetics of IDB-011

Effects of Intravenous Acetaminophen on Body Temperature and Hemodynamic Responses in Febrile Critically Ill Adults

Penetration-enhanced Direct DBD Non-thermal Plasma for Hair Loss

PPV to Guide Fluid Management in the PICU

A Safety and Efficacy Study of OnabotulinumtoxinA in Premature Ejaculation

Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Crow's Feet Lines

A Safety and Efficacy Study of OnabotulinumtoxinA in Upper Facial Rhytides

PEMF and PEC Blocks in Mastectomy Reconstruction Patients

Dexamethasone for Post Cesarean Delivery Analgesia

The Effect of Platelet Rich Plasma on Non-scarring Alopecia

Efficacy of Intravenous Lidocaine in the Operative Management of Thyroid Surgery With Intraoperative Nerve Monitoring

Age Comparisons of Exercising Muscle O2 Supply in Healthy Adults: Effects of Esmolol Infusion

Non-invasive Tear Film Dynamic Measurements in Normal, MGD and ADDE Subjects After Saline Instillation

Effect of Tranexamic Acid (TXA) Administered Prior to Shoulder Arthroscopy on Postoperative Pain Medication Usage: A Randomized Controlled Trial

Treatment of Symptomatic Lumbar Internal Disc Disruption (IDD) With the Biostat® System