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Showing 1–24 of 90 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: OMT (osteopathic manipulative treatment) Clear all
Not listed Not applicable Interventional

Diabetes and Osteopathic Manipulative Medicine (OMM)

NCT03663322
View directory record Official record
Conditions
Type2 Diabetes Mellitus, Osteopathy in Diseases Classified Elsewhere
Interventions
OMT Protocol, OMT-Sham Protocol
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
30 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Central Islip, New York • Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated May 1, 2022 · Synced Sep 29, 2026, 8:37 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Techniques for the Treatment of Chronic Migraine Headaches

NCT04520425
View directory record Official record
Conditions
Chronic Migraine, Headache
Interventions
Osteopathic manipulative therapy
Procedure
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 29, 2026, 8:37 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Acute Low Back Pain in the Emergency Department Treated With Osteopathic Manipulative Treatment Versus NSAIDs

NCT04129437
View directory record Official record
Conditions
Low Back Pain
Interventions
Ibuprofen, Osteopathic manipulative treatment
Drug · Procedure
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 6, 2022 · Synced Sep 29, 2026, 8:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Medicine in Pregnancy: Physiologic and Clinical Effects

NCT00426244
View directory record Official record
Conditions
Low Back Pain, Pregnancy
Interventions
Osteopathic Manipulative Treatment, Placebo Ultrasound
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Sep 29, 2026, 8:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

By Potentially Adding a Century Old Therapeutic Measure to Pain Treatment Regimens Called Osteopathic Manipulative Treatment, Can Help Decrease Muscle and Bone Pain and the Usage of Opioid Pain Medication.

NCT06930196
View directory record Official record
Conditions
Osteopathic Manipulative Treatment
Interventions
Counterstrain, Muscle Energy, High Velocity Low Amplitude, The Ultralign SA201 used for measuring tissue texture changes, IsoTouch
Other · Device
Lead sponsor
Skagit Regional Health
Other
Eligibility
18 Years to 65 Years
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Sep 29, 2026, 8:37 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Treatment and Migraine Headaches

NCT04976985
View directory record Official record
Conditions
Chronic Migraine, Migraine Disorders, Headache Disorders, Headache, Migraine
Interventions
Osteopathic Manipulative Therapy (OMT), Standard of care
Procedure · Other
Lead sponsor
St. Luke's Hospital, Pennsylvania
Other
Eligibility
18 Years to 50 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 2, 2021 · Synced Sep 29, 2026, 8:37 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Physical Exam, Static & Dynamic Ultrasound Assessment, & Treatment of Thoracolumbar Fascia (TLF) Mediated Low Back Pain

NCT06818175
View directory record Official record
Conditions
Low Back Pain, Chronic Low-back Pain, Acute Low Back Pain
Interventions
Ultrsound Guided Hydrodissection of the Thoracolumbar Fascia, Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 50 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 29, 2026, 8:37 AM EDT
Not listed Not applicable Interventional

Effects of a Single Osteopathic Manipulative Treatment (OMT) on Intraocular Pressure (IOP) Reduction

NCT03590249
View directory record Official record
Conditions
Glaucoma
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Sep 29, 2026, 8:37 AM EDT
Completed Not applicable Interventional

OMT vs. Standard Therapy in the Management of Acute Neck and Low Back Pain in the Emergency Department

NCT06987578
View directory record Official record
Conditions
Acute Pain
Interventions
OMT vs. Ibruprofen
Other
Lead sponsor
St. Joseph's Regional Medical Center, New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Paterson, New Jersey
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Sep 29, 2026, 8:37 AM EDT
Recruiting Phase 1Phase 2 Interventional

Treating Chronic Cervicogenic Head and Neck Pain

NCT05617365
View directory record Official record
Conditions
Cervicogenic Headache, Neck Pain, Posterior
Interventions
Osteopathic Manipulative Therapy and Exercise Therapy
Combination Product
Lead sponsor
Michigan State University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 29, 2026, 8:37 AM EDT
Withdrawn Not applicable Interventional

Osteopathic Manipulative Treatment for Recurrent Mastitis

NCT05132426
View directory record Official record
Conditions
Mastitis
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Western University of Health Sciences
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 29, 2026, 8:37 AM EDT
Recruiting Not applicable Interventional

Comparing Efficacy of Osteopathic Manipulation vs. Wrist Immobilization for Carpal Tunnel Syndrome

NCT07432750
View directory record Official record
Conditions
Carpal Tunnel Syndrome (CTS)
Interventions
Osteopathic Manipulative Treatment, Wrist Immobilizer
Procedure · Device
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 29, 2026, 8:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Osteopathic Manipulative Treatment (OMT) on Proprioception in Adults

NCT04374227
View directory record Official record
Conditions
Osteopathy in Diseases Classified Elsewhere
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
Des Moines University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Sep 29, 2026, 8:37 AM EDT
Recruiting Not applicable Interventional

Effects of Osteopathic Manipulative Treatment Protocol on Sleep Quality in Parkinson's Disease Subjects

NCT06671600
View directory record Official record
Conditions
Parkinsons Disease, Sleep
Interventions
Osteopathic Manipulative Treatment, Sham (No Treatment)
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 29, 2026, 8:37 AM EDT
Terminated Not applicable Interventional

OMT of Somatic Dysfunction and Chronic Low Back Pain in Patients With Type 2 Diabetes Mellitus

NCT02054650
View directory record Official record
Conditions
Chronic Low Back Pain, Type 2 Diabetes Mellitus
Interventions
Osteopathic Manual Treatment (OMT), Sham OMT
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years to 79 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2016 · Synced Sep 29, 2026, 8:37 AM EDT
Completed Not applicable Interventional

Effect of OMT on Asthma Symptoms in Southwest Virginia

NCT00545376
View directory record Official record
Conditions
Asthma
Interventions
Osteopathic Manipulative Treatment - in clinic, Osteopathic Manipulative Treatment - at home, Education to physicians
Procedure · Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
5 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 21, 2019 · Synced Sep 29, 2026, 8:37 AM EDT
Completed Not applicable Interventional

The Effect of OMT on Patients With COPD: Correlating Pulmonary Function Tests With Biochemical Alterations

NCT01582958
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Osteopathic Manipulative Treatment (OMT), sham omt
Procedure · Other
Lead sponsor
Michigan State University
Other
Eligibility
49 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 7, 2015 · Synced Sep 29, 2026, 8:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Therapy Effects on Prolonged Post-COVID Olfactory Dysfunction

NCT05112887
View directory record Official record
Conditions
COVID-19 Lower Respiratory Infection, SARS-CoV2 Infection
Interventions
Osteopathic Manipulative Therapy
Other
Lead sponsor
Ohio University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Dublin, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Sep 29, 2026, 8:37 AM EDT
Completed Not applicable Interventional

Preventative Osteopathic Manipulative Treatment (OMT) and the Nursing Home Patient

NCT01000142
View directory record Official record
Conditions
General Health Status
Interventions
Osteopathic Manipulative Treatment, Light Touch
Procedure
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
65 Years to 100 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Kirksville, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Sep 29, 2026, 8:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Augmentation of Immune Response to COVID-19 mRNA Vaccination Through OMT With Lymphatic Pumps

NCT04928456
View directory record Official record
Conditions
Covid19
Interventions
Osteopathic Manipulative Treatment (OMT)
Other
Lead sponsor
Western University of Health Sciences
Other
Eligibility
18 Years to 65 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Sep 29, 2026, 8:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of OMT on Gait Kinematics and Postural Control in Parkinson Disease

NCT04946760
View directory record Official record
Conditions
Parkinson Disease
Interventions
Sham Manipulation
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
50 Years and older
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Sep 29, 2026, 8:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing the Impact of OMT on Physician Pain

NCT05488158
View directory record Official record
Conditions
Pain
Interventions
Osteopathic manipulation
Other
Lead sponsor
Fort Wayne Medical Education Program
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 3, 2022 · Synced Sep 29, 2026, 8:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Treatment and Its Relationship to Autonomic Nervous System Activity

NCT00516984
View directory record Official record
Conditions
Healthy
Interventions
Placebo, Sham, OMT
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
19 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 21, 2008 · Synced Sep 29, 2026, 8:37 AM EDT
Completed Early Phase 1 Interventional Results available

The Effectiveness of Osteopathic Manipulative Medicine in the Management of Headaches Associated With Post Concussion Syndrome

NCT04732338
View directory record Official record
Conditions
Headache, Post-Concussion Syndrome
Interventions
Osteopathic Manipulative Therapy
Other
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Edison, New Jersey
Source: ClinicalTrials.gov public record
Updated May 24, 2021 · Synced Sep 29, 2026, 8:37 AM EDT