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ClinicalTrials.gov public records Last synced Oct 16, 2026, 10:45 AM EDT

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Showing 1297–1320 of 2,136 matching trials from the local directory fallback.

Filters: Intervention: ONE Clear all

Conditions: Postoperative Pain, Recovery
Interventions: Intravenous Methadone, Short-acting Opioids Intraoperative analgesia; Drug
Lead sponsor: Alexandre P. Joosten; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Irvine, California

Conditions: Mental Well-being, Resilience, Psychological
Interventions: Intervention WONE App (full Version); Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 260 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Stanford, California

Conditions: Toxicant Induced Chronic Multisymptom Illness and Associated Symptoms and Comorbidities
Interventions: Placebo, Ubiquinone 100 mg Oral Soft Gel; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Hip Arthritis, Hip Dysplasia, Hip Osteoarthritis, Hip Pain Chronic, Psychosocial Problem
Interventions: Cell Phone Based Cognitive Based Therapy (Pacifica App), Control; Device · Other
Lead sponsor: Michael C Willey; Other
Eligibility: 15 Years to 39 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Retinal Disease
Interventions: IRX-101, Providone-Iodine; Drug
Lead sponsor: iRenix Medical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Forehead; Wound
Interventions: Group 1 cannabidiol (CBD) with silicone ointment, Group 2 silicone patch; Biological
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 99 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Post Cataract Surgery
Interventions: Triamcinolone (Optional), control group; Drug
Lead sponsor: Research Insight LLC; Industry
Eligibility: 22 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Laguna Hills, California

Conditions: Work of Breathing
Interventions: Cold temperature environment, Hot temperature environment, Thermoneutral temperature environment; Other
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2028 – 2029
U.S. locations: 1
States / cities: Bloomington, Indiana

Conditions: Fentanyl, Opioid Use Disorder
Interventions: Injectable buprenorphine, Sublingual Buprenorphine (SUBOXONE, Zubsolv, or generic tablets); Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Bronchopulmonary Dysplasia (BPD), Respiratory Distress Syndrome (RDS)
Interventions: Betamethasone; Drug
Lead sponsor: Khang Nguyen; Other
Eligibility: Up to 28 Weeks
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Valhalla, New York

Conditions: Aging, Postmenopause
Interventions: Mitoquinone (MitoQ), Placebo; Dietary Supplement
Lead sponsor: Colorado State University; Other
Eligibility: 60 Years and older · Female only
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Fort Collins, Colorado

Conditions: Hyperinsulinemia, Insulin Resistance, Metabolic Dysfunction Associated Steatotic Liver Disease, Non-Alcoholic Fatty Liver Disease, Obesity, Prediabetic State
Interventions: 20% D-glucose (aq), Glucagon, Growth Hormone, Human, Harvard Apparatus PHD ULTRA CP syringe pump, Insulin human, KIND Bar, Nestle BOOST Plus, Octreotide Acetate, Yellow Springs Instruments (YSI) 2500 Biochemistry Glucose/Lactate Analyzer, [1-13C1] sodium acetate, [6,6-2H2] D-glucose; Drug · Device · Dietary Supplement + 1 more
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: New York, New York

Conditions: Early Life Trauma, Major Depressive Diorder
Interventions: Lumateperone 42 mg, Placebo; Drug · Other
Lead sponsor: University of Texas at Austin; Other
Eligibility: 21 Years to 70 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Hypogonadism, Male
Interventions: Testosterone Cypionate Injection 200 mg/mL; Drug
Lead sponsor: Azurity Pharmaceuticals; Industry
Eligibility: 18 Years to 75 Years · Male only
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 6
States / cities: Birmingham, Alabama • DeLand, Florida • Hialeah, Florida + 3 more

Conditions: Prostate Cancer
Interventions: Darolutamide, Physician choice Androgen Deprivation (Hormone) Therapy; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older · Male only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Opioid Use Disorder
Interventions: Active rTMS, Placebo, Sham rTMS, Yohimbine + Hydrocortisone; Device · Drug
Lead sponsor: Wayne State University; Other
Eligibility: 21 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Glaucoma
Interventions: Rocklatan eye drops will be instilled nightly in one eye diagnosed with glaucoma for up to 12 months., Two optical coherence tomography (OCT) devices will be used to assess blood flow changes.; Drug · Device
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 21 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Hypertension, Preeclampsia
Interventions: Drospirenone, Norethindrone 0.35 MG; Drug
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Pain, Placebo Effect, Rejection
Interventions: Control Cream with Naloxone, Control Cream with Saline, Placebo Cream with Naloxone, Placebo Cream with Saline; Drug
Lead sponsor: Trustees of Dartmouth College; Other
Eligibility: 18 Years to 55 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Hanover, New Hampshire

Conditions: Chronic Rhinosinusitis
Interventions: budesonide lavage via NeilMed, nebulized budesonide via NasoNeb; Combination Product
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Type 2 Diabetes
Interventions: Standard of Care (SOC), phone application; Other · Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 10 Years to 21 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 2
States / cities: Oakland, California • San Francisco, California

Conditions: Skin Texture
Interventions: PLLA, Sterile Water as control, microneedling RF treatment; Device · Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Dyspareunia, Lichen Sclerosus of Vulva, Vulvodynia
Interventions: Estradiol 0.01% Vag Cream, testosterone 0.1% and estradiol 0.01% vaginal cream; Drug
Lead sponsor: TriHealth Inc.; Other
Eligibility: 18 Years and older · Female only
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Cincinnati, Ohio

Conditions: Chronic Stroke Patients, Chronic Stroke Survivors, Stroke
Interventions: Robot assisted gait training alone, Robot-assisted gait training and transcutaneous spinal cord stimulation in chronic non-ambulatory stroke survivors: pilot RCT trial; Device
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Kansas City, Kansas

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Methadone for Enhanced Postoperative Analgesia in Intermediate-Risk Noncardiac Surgery (MELODY)

Evaluating a Digital Intervention to Improve Resilience and Reduce Stress in Stanford Populations

Mitigating Toxic Impact: The Role of Coenzyme Q10 in Post-Exposure Protection

Psychosocial Interventions for Young Adults With Hip Pain

Safety and Tolerability of IRX-101 in Patients Receiving Intravitreal Injections

Topical CBD Scar Outcomes Study

The TRIBECA Study (TRIessence/Byqlovi for Easier CAtaract Surgery)

The Role of Environmental Temperatures in Respiratory Control

Comparing Outpatient Treatment Retention Among Individuals Using Fentanyl Randomized to Low-dose and Direct-to-inject Buprenorphine Initiation

Can Betamethasone Given After Birth Help Extremely Premature Babies Come Off Breathing Support Safely and Effectively?

Oral Antioxidant Therapy Targeted to the Mitochondria for Improving Brain Artery Health in Postmenopausal Women

Human Models of Selective Insulin Resistance: Pancreatic Clamp

Neurocircuitry Mechanisms and Efficacy of Lumateperone as Adjunctive Therapy for Major Depressive Disorder and History of Early Life Abuse

Ambulatory Blood Pressure Monitoring (ABPM) Study in Hypogonadal Men

Evaluating Treatment Outcomes Using Darolutamide and Androgen Deprivation Therapy in Patients With Metastatic Hormone-Sensitive Prostate Cancer.

Effects of Pharmacological Stress and rTMS on Executive Function in Opioid Use Disorder

Rocklatan Retinal Perfusion OCT Study

A Randomized Feasibility Trial Comparing Drospirenone and Norethindrone for Postpartum Hypertension Management in Preeclampsia

The Role of the Opioid System in Placebo Effects on Pain and Social Rejection

Nebulized Nasal Steroids

Artificial Intelligence-based Methods to Predict Disease Progression in Youth With Type 2 Diabetes

Characterization of Skin and Facial Fat Pad Thickness Changes Following Microneedling Radiofrequency With and Without Topical Poly-L-Lactic Acid for Facial Rejuvenation

Use of Topical Testosterone and Estrogen vs Estrogen Alone in Vulvodynia: a Randomized Controlled Trial

Walking and tSCS in Non-ambulatory Stroke Survivors