Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 7, 2026, 11:46 PM EDT

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Showing 1–7 of 7 matching trials from the live ClinicalTrials.gov search.
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Conditions
Refractive Errors
Interventions
LID021201 contact lenses, OPTI-FREE multipurpose solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
3
States / cities
Maitland, Florida • Memphis, Tennessee • Wichita Falls, Texas
Conditions
Myopia, Astigmatism, Refractive Error
Interventions
OPTI-FREE RepleniSH multipurpose solution, ReNu Biotrue multipurpose solution, Silicone hydrogel contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Not applicable Interventional Results available

Clinical Biocompatibility Evaluation of Contact Lens Coatings

NCT03034928
Conditions
Refractive Errors, Ametropia
Interventions
Contact lens with investigational coating 1, Balafilcon A contact lens, OPTI-FREE® RepleniSH® MPDS, Contact lens with investigational coating 2
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Johns Creek, Georgia
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions

NCT01024855
Conditions
Myopia, Hyperopia, Astigmatism
Interventions
RevitaLens OcuTec MPS (Investigational MPS) and Opti-Free RepleniSH MPS (control)
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Santa Ana, California
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface

NCT01250925
Conditions
Myopia, Refractive Error
Interventions
ReNu MultiPlus® MultiPurpose Solution, OPTI-FREE® RepleniSH®, Clear Care®
Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
2
States / cities
Iowa City, Iowa • Boston, Massachusetts
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Evaluation of an Investigational Multi-Purpose Solution (MPS)

NCT00961051
Conditions
Study Focus is Healthy Contact Lens Wearers
Interventions
Investigational MPS, Opti-Free
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
9
States / cities
San Diego, California • Waipahu, Hawaii • Warrensburg, Missouri + 6 more
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Multipurpose disinfection solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
3
States / cities
Orlando, Florida • Bloomington, Illinois • Powell, Ohio