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ClinicalTrials.gov public records Last synced Nov 7, 2026, 6:17 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 212 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: OUD Clear all

Conditions: Pregnancy, Postpartum Period, Opioid Use Disorder
Interventions: Usual Care, Adapted Collaborative Care Model (CCM); Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 1,350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Opioid Use, Pregnancy
Interventions: In-Person Perinatal OUD Treatment, Perinatal OUD Treatment via Telemedicine; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Opioid-use Disorder, Mental Health Conditions
Interventions: Collaborative Care for Opioid Use Disorders and Mental Health Conditions, Augmented Usual Care, Collaborative Care for Opioid Use Disorders and Mental Health Conditions Plus Certified Recovery Specialists; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 567 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Opioid-use Disorder
Interventions: MOUD Pre-Treatment Telehealth, MOUD Pre-Treatment Telehealth and Peer Navigator, Services as Usual; Behavioral · Other
Lead sponsor: Michele Staton; Other
Eligibility: 18 Years and older · Female only
Enrollment: 900 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2026
U.S. locations: 9
States / cities: Elizabethtown, Kentucky • Harlan, Kentucky • Henderson, Kentucky + 6 more

Conditions: Opioid Use Disorder, Chronic Pain, Anxiety
Interventions: Virtual Tai Chi Easy; Behavioral
Lead sponsor: Asana Recovery; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Costa Mesa, California

Conditions: Opioid Use Disorder
Interventions: Placebo, Cannabidiol (CBD) 200mg, Cannabidiol (CBD) 400mg; Drug
Lead sponsor: Yasmin Hurd; Other
Eligibility: 18 Years to 65 Years
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Opioid-Related Disorders, Drug Abuse
Interventions: Contingency management, Cognitive-Behavior Therapy Modules, Peer Contingency Management (CM) Guide, Drug testing, Wellness modules, Peer technical support; Behavioral
Lead sponsor: Western Michigan University; Other
Eligibility: 18 Years and older
Enrollment: 97 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Kalamazoo, Michigan

Conditions: Opioid Use Disorder
Interventions: Patient Decision Aid; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Tarzana, California

Conditions: Opioid Use Disorder
Interventions: HC-MOUD Only, BT-MOUD with Buprenorphine; Behavioral
Lead sponsor: Howard University; Other
Eligibility: 16 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 4
States / cities: Washington D.C., District of Columbia • Miami, Florida • Chicago, Illinois + 1 more

Conditions: Opioid Use Disorder, Cigarette Smoking
Interventions: Telehealth Motivational Counseling, Nicotine Replacement Product, National Institute on Drug Abuse (NIDA) Standardized Research Electronic Cigarette (SREC).; Behavioral · Drug · Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 21 Years to 75 Years
Enrollment: 302 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: New York, New York • The Bronx, New York

Conditions: Opioid Use Disorder
Interventions: 3D Therapy Thrive; Device
Lead sponsor: 3D Therapy, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Quincy, Massachusetts

Conditions: Opioid Use Disorder
Interventions: AZD4041, Itraconazole, Buprenorphine, Buprenorphine / Naloxone, Hydromorphone, Placebo; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Opioid Use Disorder
Interventions: Peer Support Checklist; Behavioral
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 2
States / cities: Clinton, South Carolina • Seneca, South Carolina

Conditions: Opioid-use Disorder, Opioid Use, Unspecified, Buprenorphine Dependence
Interventions: Subutex / Buprenorphine, Fetal & Neonatal MRI, DNA/Genetic/Pharmacokenetic Blood Draws; Drug · Diagnostic Test
Lead sponsor: Senthil Sadhasivam; Other
Eligibility: 18 Years and older · Female only
Enrollment: 600 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Opioid Use Disorder, Stimulant Use Disorder
Interventions: Suvorexant (dual orexin receptor antagonist), Placebo; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Opioid-Related Disorders, Opioid Dependence, Opioid Addiction, Opioid Withdrawal
Interventions: Bridge Device, Lofexidine, Placebo, Sham Bridge Device; Device · Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Opioid Use Disorder
Interventions: Tezampanel, Placebo; Drug
Lead sponsor: Proniras Corporation; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Opioid Use Disorder, Serious Bacterial Infections
Interventions: Smart IOP Intervention, Peer Recovery Coach; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Opioid-use Disorder, Medication Adherence
Interventions: Youth Opioid Recovery Support (YORS); Behavioral
Lead sponsor: Potomac Health Foundations; Other
Eligibility: 18 Years to 28 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Opioid Use Disorder
Interventions: Youth Opioid Recovery Support (YORS); Behavioral
Lead sponsor: Potomac Health Foundations; Other
Eligibility: 13 Years to 21 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Opioid Use Disorder
Interventions: OUD treatment intervention; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 99 Years
Enrollment: 400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Opioid-use Disorder, Contingency Management, Medication for Opioid-use Disorder
Interventions: Software Application; Other
Lead sponsor: Q2i, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Opioid Use Disorder (OUD)
Interventions: Observational study with MRI/EEG; Other
Lead sponsor: University of California, Irvine; Other
Eligibility: 21 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Irvine, California

Conditions: Opioid Overdose Prevention, HIV Prevention and Care, Harm Reduction
Interventions: PROTECT-ED Care Coordination; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Search by objective public record fields.

Impact of Collaborative Care for Pregnant Women With Opioid Use Disorder in Low-Resource Obstetric Settings

Perinatal Opioid Use

The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions

Kentucky Women's Justice Community Opioid Innovation Network

Tai Chi Easy for Opioid Use Disorder, Anxiety, and Chronic Pain

Cannabidiol in the Treatment of Opioid Use Disorder

OUD Smartphone Services

Pilot Test of Patient Decision Aid for Opioid Use Disorder

Integrating MOUD in Nonmedical Community Settings (Better Together)

E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder

The Feasibility of VR for OUD

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

STAMPS: South Carolina Buprenorphine Treatment Initiation, Adherence, and Retention Utilizing Mobile Health Units and Peer Support Specialists

Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes

Suvorexant for Opioid/Stimulant Co-use

An Innovative Intervention for OUD Treatment

Study to Assess the Use of Tezampanel for Opioid Withdrawal Syndrome in Treatment-Seeking Patients With Opioid Use Disorder

Pilot Testing a Novel Remotely Delivered Intensive Outpatient Program for Individuals With OUD

The Youth Opioid Recovery Support (YORS) Intervention

Expanding the Youth Opioid Recovery Support (YORS) Intervention for MOUD Adherence to Adolescents With OUD

A Multi-site Intervention to Expand Hospital Based OUD Treatment Provision

Usability Testing for the Reward-based Technology to Improve OUD Treatment

Mapping Ibogaine Neural Dynamics in Opioid Use Disorder

Prevention and Rapid Outreach for Treatment, Engagement, and Care Transition From the Emergency Department