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ClinicalTrials.gov public records Last synced Nov 7, 2026, 6:48 AM EST

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Showing 169–192 of 212 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: OUD Clear all

Conditions: Overdose Risk, Opioid Use Disorder, Stimulant Use Disorders
Interventions: Overdose Prevention Intervention Package (OPIP); Behavioral
Lead sponsor: Michele Staton; Other
Eligibility: 18 Years and older · Female only
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 3
States / cities: Barbourville, Kentucky • Harlan, Kentucky • Hyden, Kentucky

Conditions: Opioid-use Disorder
Interventions: Interview, Surveys; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older · Female only
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Opioid Use Disorder, Medication Adherence, Polysubstance Drug Use (Indiscriminate Drug Use), Methamphetamine-dependence
Interventions: Patient Navigation and mHealth (PN+mHealth); Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Substance Use Disorder (SUD)
Interventions: real-time functional magnetic resonance imaging (rt-fMRI) neurofeedback; Device
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Opioid-Use Disorder (OUD)
Interventions: Team Intervention; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 130 Years
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 2
States / cities: New Haven, Connecticut

Conditions: Opioid Use Disorder
Interventions: [14C]IDV184001AN; Drug
Lead sponsor: Indivior Inc.; Industry
Eligibility: 19 Years to 55 Years · Male only
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Opioid Use Disorder, Infectious Disease, Risk Reduction Behavior, Substance Use, Substance Abuse, Stimulant Use Disorder
Interventions: Patient Navigator, Mobile Health Unit; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 601 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 3
States / cities: New Haven, Connecticut • Dallas, Texas • Fort Worth, Texas

Conditions: Opioid-use Disorder, Stress Related Disorder, Anxiety, Pain Interference
Interventions: Live-Online M-ROCC, Live-Online Control; Behavioral
Lead sponsor: Cambridge Health Alliance; Other
Eligibility: 18 Years to 70 Years
Enrollment: 260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Somerville, Massachusetts

Conditions: Opioid Use Disorder
Interventions: NYX-783, Placebo, Oxycodone; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 58 Years
Enrollment: 9 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 2
States / cities: New Haven, Connecticut

Conditions: Opioid Use Disorder, Neonatal Abstinence Syndrome
Interventions: An implementation model for co-located Medications for Opioid Use Disorder (MOUD) prescription in the NICU; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 3
States / cities: Philadelphia, Pennsylvania

Conditions: Opioid Use Disorder
Interventions: Wiidookaage'win Facebook Group; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Post Traumatic Stress Disorder, Opioid-use Disorder
Interventions: Lofexidine, Placebo oral tablet; Drug
Lead sponsor: Pharmacotherapies for Alcohol and Substance Use Disorders Alliance; Other
Eligibility: 18 Years to 70 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Houston, Texas • San Antonio, Texas

Conditions: Chronic Pain, Opioid Use Disorder, Opioid Misuse and Addiction
Interventions: Usual Care, Pain Self-Management; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 204 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 17
States / cities: Baltimore, Maryland • Allison Park, Pennsylvania • Blawnox, Pennsylvania + 9 more

Conditions: Perinatal Opioid Use Disorder, Opioid Use Disorder
Interventions: Penny COPILOT; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Opioid-use Disorder
Interventions: Active repetitive transcranial magnetic stimulation (rTMS), Sham repetitive transcranial magnetic stimulation (rTMS); Device
Lead sponsor: Rutgers University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 81 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Opioid Use Disorder, Opioid Use
Interventions: Sub-acute stabilization; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 40,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Opioid Abuse
Interventions: Implementation of the BINDeR-Tx service model; Behavioral
Lead sponsor: Jerry Cochran; Other
Eligibility: 18 Years and older
Enrollment: 65 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Opioid Use Disorder, Bloodstream Infection, Osteomyelitis, Endocarditis, Septic Arthritis, Epidural Abscess
Interventions: RETAIN, Unrelated videos; Other
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Opioid-use Disorder, Cocaine Use Disorder
Interventions: Cariprazine 1.5 MG, Placebo; Drug
Lead sponsor: Kyle Kampman; Other
Eligibility: 18 Years to 65 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Opioid Use Disorder
Interventions: Telehealth for opioid use disorder treatment delivery; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Alcohol Use Disorder, Opioid Use Disorder, Alcohol Use, Opioid Use
Interventions: Brief opioid-informed alcohol treatment; Behavioral
Lead sponsor: University of Notre Dame; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Notre Dame, Indiana

Conditions: Opioid Use Disorder
Interventions: SUN, SUN + Telebridge, ED-ITT, ED-ITT + BHS; Behavioral
Lead sponsor: RAND; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Colton, California

Conditions: Opioid Overdose
Interventions: RELAY; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 99 Years
Enrollment: 253 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Opioid Use Disorder, Opioid Withdrawal
Interventions: Addinex; Device
Lead sponsor: Addinex Technologies, Inc.; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Greenwich, Connecticut

Search by objective public record fields.

Kentucky Women's Justice Community Overdose Innovation Network - Phase II

Obstetric Pain Management for Women With Opioid Use Disorder (QUEST)

MHealth Incentivized Adherence Plus Patient Navigation

Real-time Opioid Study

SafetyNet Program for Opioid Use Disorder (OUD)

Single Dose Study of [14C]-IDV184001AN ([14C]-IDV184001) in Healthy Adult Male Participants

Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among Justice-involved Populations

Effect of Mindfulness on Opioid Use and Anxiety During Primary Care Buprenorphine Treatment (R33 Phase)

Safety, Tolerability and Pharmacokinetics of NYX-783 and Oxycodone DDI Study

An Intervention Mapping Approach to Closing the Gap in Maternal OUD and Infant NAS Care (SUPPORT)

Using Facebook to Support Opioid Recovery Among American Indian Women

Lofexidine Combined With Buprenorphine for Reducing Symptoms of PTSD and OU Relapse in Veterans

Pain Self-Management and Treatment Engagement for Patients Taking Opioids

Adapting the Penny Chatbot for Perinatal OUD Patients: COPILOT

Using Combined EEG and Non-invasive Brain Stimulation to Examine and Improve Reward Functioning in Opioid Use Disorder

Overdose Recovery and Care Access (ORCA) Qualitative Stakeholder Interviews and County-level Data

Buprenorphine Induction and Naloxone Distribution Program-Combined With Warm Hand-Off Referral to Continued Treatment

Retention and Re-Engagement in Treatment for Addiction Following Serious Injection Related Infections (RETAIN)

Cariprazine for Comorbid Cocaine and Opioid Use Disorder

Improving Access to Opioid Use Disorder Treatment Among Marginalized Patients With a Tailored Telehealth Intervention

Better Experiences in Substance Treatment: A Brief Alcohol-focused Intervention Tailored for Patients in Opioid Agonist Treatment

Adaptive Interventions for Emergency Department Patients With Opioid Use Disorder

Multi-Center Randomized Controlled Trial of Relay- NYC's Nonfatal Overdose Response Program

Suboxone Dispenser for OUD