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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:30 PM EDT

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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: OUD screening Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Kentucky Women's Justice Community Overdose Innovation Network - Phase II

NCT07179614
View directory record Official record
Conditions
Overdose Risk, Opioid Use Disorder, Stimulant Use Disorders
Interventions
Overdose Prevention Intervention Package (OPIP)
Behavioral
Lead sponsor
Michele Staton
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
3
States / cities
Barbourville, Kentucky • Harlan, Kentucky • Hyden, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 21, 2026, 1:30 PM EDT
Terminated Not applicable Interventional Results available

Reward-based Technology to Improve OUD Treatment

NCT05180669
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
OARSCM Software Application, MyMAT Software Application
Other
Lead sponsor
Q2i, LLC
Industry
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 21, 2026, 1:30 PM EDT
Completed Not applicable Interventional Results available

Treatment of Pregnant Women With OUD

NCT04240392
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Collaborative Care (CC), Extension for Community Healthcare Outcomes (ECHO)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
11
States / cities
Hartford, Connecticut • New Britain, Connecticut • New Haven, Connecticut + 7 more
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Oct 21, 2026, 1:30 PM EDT
Not yet recruiting Not applicable Interventional

Improving Access to Opioid Use Disorder Treatment Among Marginalized Patients With a Tailored Telehealth Intervention

NCT06341608
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Telehealth for opioid use disorder treatment delivery
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 21, 2026, 1:30 PM EDT
Completed Not applicable Interventional Results available

Clinical Decision Support to Implement ED-initiated Buprenorphine for OUD

NCT03658642
View directory record Official record
Conditions
Clinical Decision Support, Buprenorphine, Opioid-use Disorder
Interventions
Clinical Decision Support (CDS)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
5,047 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
22
States / cities
Birmingham, Alabama • Gardendale, Alabama • Aurora, Colorado + 17 more
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Oct 21, 2026, 1:30 PM EDT
Recruiting Not applicable Interventional

Building Retention and Initiation Through Delivery of Peer-Guided Evidence-Based Practices

NCT07541417
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Certified Peer Support Specialist Intervention
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 21, 2026, 1:30 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Chicago Data-driven Opioid Use Disorder Screening, Engagement, Treatment and Planning System

NCT07498322
View directory record Official record
Conditions
Opiod Use Disorder
Interventions
OUD screening, MOUD, Continuity of care
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
16 Years and older
Enrollment
271,031 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 21, 2026, 1:30 PM EDT
Suspended Not applicable Interventional

Neuroplasticity in Maternal Opioid Use Disorder (OUD)

NCT05495984
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
ERPs with electroencephalography (EEG), MIO
Behavioral
Lead sponsor
Yale University
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 21, 2026, 1:30 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The STop UNhealthy Substance Use Now Trial

NCT06524232
View directory record Official record
Conditions
Risky Health Behavior, Substance Use Disorders, Substance Abuse, Alcohol Use Disorder, Drinking, Alcohol, Substance Use
Interventions
Practice Facilitation (PF), Learning Collaborative (LC), Performance Incentives (PI)
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
3
States / cities
Cincinnati, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 21, 2026, 1:30 PM EDT
Active, not recruiting Not applicable Interventional

Buprenorphine Integration Research and Community Health

NCT05668780
View directory record Official record
Conditions
Opioid Use Disorder, HIV Infections, Hepatitis C
Interventions
NIATx Coaching
Behavioral
Lead sponsor
Yale University
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 21, 2026, 1:30 PM EDT
Completed Not applicable Interventional Results available

Collaborating to Heal Addiction and Mental Health in Primary Care

NCT04600414
View directory record Official record
Conditions
Opioid-use Disorder, Mental Health Disorder
Interventions
Collaborative Care for Mental Health Symptoms, Collaborative Care for Opioid Use Disorder and Mental Health Symptoms
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
33
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • Dunwoody, Georgia + 22 more
Source: ClinicalTrials.gov public record
Updated Oct 3, 2025 · Synced Oct 21, 2026, 1:30 PM EDT
Completed No phase listed Observational

Emergency Department Connection to Care With Buprenorphine for Opioid Use Disorder

NCT03544112
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Employ a multifaceted approach to facilitate clinical protocol implementation, Initiate BUP (SL-BUP or XR-BUP) in the ED
Behavioral · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
4
States / cities
Claremont, New Hampshire • Manchester, New Hampshire • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 30, 2019 · Synced Oct 21, 2026, 1:30 PM EDT
Completed Not applicable Interventional

An Integrated Intervention Involving Recovery Coaching and Cognitive Behavioral Therapy for Opioid Use Disorder

NCT06102200
View directory record Official record
Conditions
Standard of Care, Standard of Care + CBT4CBT, Standard of Care + CBT4CBT + RC
Interventions
CBT4CBT, RC, Sandard of care
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 21, 2026, 1:30 PM EDT
Completed Not applicable Interventional Results available

Usability Testing for the Reward-based Technology to Improve OUD Treatment

NCT05159362
View directory record Official record
Conditions
Opioid-use Disorder, Contingency Management, Medication for Opioid-use Disorder
Interventions
Software Application
Other
Lead sponsor
Q2i, LLC
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 30, 2023 · Synced Oct 21, 2026, 1:30 PM EDT
Completed Not applicable Interventional

Opioid Treatment and Peer Recovery Support

NCT04978168
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Core Intervention, Peer Support Specialists (PSS), Treatment as Usual (TAU)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 21, 2026, 1:30 PM EDT
Enrolling by invitation Not applicable Interventional

Developing and Testing Innovative Care Pathways for Screening and Treatment of OUD/PTSD in Jails

NCT07490717
View directory record Official record
Conditions
Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms, Opioid Use Disorder (OUD), Stimulant Use Disorder, Stimulant Use & Co-occuring Opioid Use Disorders, Co-occurring Mental and Substance Use Disorders, Medications for Opioid Use Disorder
Interventions
Cognitive Processing Therapy (CPT), Written Exposure Therapy (WET)
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 21, 2026, 1:30 PM EDT
Enrolling by invitation Not applicable Interventional

Pre-Pilot (R61) WINGS+++: mHealth to Improve MOUD Uptake in Women Experiencing Intimate Partner Violence and PTSD

NCT07665502
View directory record Official record
Conditions
Opioid-Related Disorders, Substance-Related Disorders, Intimate Partner Violence (IPV), Stress Disorders, Post-Traumatic, Domestic Violence, Medication for Opioid Use Disorder (MOUD), Post Traumatic Stress Disorder PTSD
Interventions
Pre-Pilot WINGS++++
Behavioral
Lead sponsor
Dawn A. Goddard-Eckrich
Other
Eligibility
18 Years and older · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
New York, New York • Newburgh, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 21, 2026, 1:30 PM EDT
Recruiting Not applicable Interventional

Expanding the Youth Opioid Recovery Support (YORS) Intervention for MOUD Adherence to Adolescents With OUD

NCT06774248
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Youth Opioid Recovery Support (YORS)
Behavioral
Lead sponsor
Potomac Health Foundations
Other
Eligibility
13 Years to 21 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Oct 21, 2026, 1:30 PM EDT
Completed Phase 2 Interventional Results available

Stimulant Oxytocin Study

NCT03016598
View directory record Official record
Conditions
Stimulant Use & Co-occuring Opioid Use Disorders
Interventions
Intranasal oxytocin, Intranasal placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Sacramento, California • San Francisco, California • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Oct 21, 2026, 1:30 PM EDT