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ClinicalTrials.gov public records Last synced Sep 20, 2026, 4:43 PM EDT

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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Occipital Nerve Stimulation Clear all
Completed No phase listed Observational

Bion Occipital Nerve Stimulation (ONS) Compassionate Use Study

NCT01050959
View directory record Official record
Conditions
Chronic, Medically Refractory Headache
Interventions
bion
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Phoenix, Arizona • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Sep 20, 2026, 4:43 PM EDT
Not yet recruiting Not applicable Interventional

Effect Of Percutaneous Electrical Nerve Field Stimulation on Symptom Control/Nervous System Activity in Patients w/Diabetes Types 1/2

NCT06783504
View directory record Official record
Conditions
Diabetes, Gastroparesis
Interventions
PERCUTANEOUS ELECTRICAL FIELD NERVE STIMULATION, Sham percutaneous electrical nerve field stimulation
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 20, 2026, 4:43 PM EDT
Completed Phase 1 Interventional

Occipital Nerve Stimulation for the Treatment of Chronic Migraine Headache.

NCT00200109
View directory record Official record
Conditions
Chronic Migraine Headache
Interventions
Occipital Nerve Stimulation
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
7
States / cities
Scottsdale, Arizona • Oceanside, California • Denver, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 11, 2011 · Synced Sep 20, 2026, 4:43 PM EDT
Terminated Phase 1 Interventional

Occipital Nerve Stimulation in the Treatment of Migraine

NCT01855672
View directory record Official record
Conditions
Migraine
Interventions
Stimulation of the Occipital Nerves
Device
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
8 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
4
States / cities
Newington, New Hampshire • New York, New York • Cincinnati, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 16, 2013 · Synced Sep 20, 2026, 4:43 PM EDT
Active, not recruiting Not applicable Interventional

The MONARCH Case Series Study: SPRINT® Peripheral Nerve Stimulation for the Treatment of Head Pain

NCT05491915
View directory record Official record
Conditions
Cervicogenic Headache, Occipital Neuralgia
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
10
States / cities
Santa Rosa, California • Waltham, Massachusetts • Rochester, Minnesota + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 20, 2026, 4:43 PM EDT
Completed Phase 1Phase 2 Interventional

Occipital Nerve Stimulation to Treat Chronic Headaches

NCT00205894
View directory record Official record
Conditions
Headache Disorders
Interventions
bion microstimulator
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
2
States / cities
Scottsdale, Arizona • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 4, 2008 · Synced Sep 20, 2026, 4:43 PM EDT
Active, not recruiting No phase listed Observational

EEG Biomarker Study for Participants in the Neurolief "MOOD" Trial

NCT05178784
View directory record Official record
Conditions
Depression
Interventions
External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) stimulation
Device
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Sep 20, 2026, 4:43 PM EDT
Completed Not applicable Interventional Results available

Treatment for Migraines With an Implantable Device

NCT00286078
View directory record Official record
Conditions
Migraine
Interventions
Precision
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
15
States / cities
Denver, Colorado • Stamford, Connecticut • Augusta, Georgia + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Sep 20, 2026, 4:43 PM EDT
Completed Not applicable Interventional

Auriculo-Nerve Stimulation on Post-Operative Opioid Requirement

NCT05506878
View directory record Official record
Conditions
Opioid Use, Auriculotherapy, Pain, Abdominal, Cancer Pain, Liver Transplant
Interventions
NSS-2 BRIDGE, Sham NSS-2 BRIDGE
Device
Lead sponsor
Jacques E. Chelly
Other
Eligibility
18 Years and older
Enrollment
286 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 20, 2026, 4:43 PM EDT
Enrolling by invitation No phase listed Observational

Utilization of 60-Day Peripheral Nerve Stimulation of the Occipital Nerves for the Treatment of Headache

NCT07553533
View directory record Official record
Conditions
Headache
Interventions
Occipital nerve peripheral nerve stimulation (PNS)
Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
New Haven, Connecticut • Old Saybrook, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 20, 2026, 4:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of a Device to Reduce Motion Sickness and Spatial Disorientation

NCT06892340
View directory record Official record
Conditions
Motion Sickness
Interventions
Transcutaneous Auricular Neurostimulation device
Device
Lead sponsor
59th Medical Wing
Federal
Eligibility
18 Years to 50 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Sep 20, 2026, 4:43 PM EDT
Completed Not applicable Interventional Results available

The RIME Study - Combined Occipital and Supraorbital Transcutaneous Nerve Stimulation for Treatment of Migraine

NCT03631550
View directory record Official record
Conditions
Acute Migraine
Interventions
Relivion active, Relivion Sham
Device
Lead sponsor
Neurolief Ltd.
Industry
Eligibility
18 Years and older
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
6
States / cities
Tempe, Arizona • Hartford, Connecticut • New Haven, Connecticut + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Sep 20, 2026, 4:43 PM EDT
Terminated Phase 1 Interventional

Study of Chiropractic and Neuromuscular Reeducation as a Treatment for Autism Symptoms

NCT01996800
View directory record Official record
Conditions
Autism
Interventions
Spinal Manipulative Therapy (SMT), SMT and Neuromuscular Reeducation
Procedure
Lead sponsor
Southern California University of Health Sciences
Other
Eligibility
5 Years to 15 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Whittier, California
Source: ClinicalTrials.gov public record
Updated Oct 3, 2016 · Synced Sep 20, 2026, 4:43 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Peri-neural Electrical Dry Needling Migraine Treatment Study

NCT04252391
View directory record Official record
Conditions
Migraine Headache
Interventions
Perineural electrical dry needling, Standard Care
Procedure
Lead sponsor
Wheaton Franciscan Healthcare
Other
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 8, 2022 · Synced Sep 20, 2026, 4:43 PM EDT
Terminated Not applicable Interventional Results available

Impact of Bridge™ Device to Treat Opioid Withdrawal Symptoms

NCT05924945
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Bridge™ active device, Bridge™ sham device
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Wernersville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Sep 20, 2026, 4:43 PM EDT
Terminated Not applicable Interventional Results available

Occipital Nerve Stimulation (ONS) for Migraine: OPTIMISE

NCT01775735
View directory record Official record
Conditions
Migraine Disorders
Interventions
Occipital nerve stimulator
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
21 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
10
States / cities
Valencia, California • Chicago, Illinois • Shreveport, Louisiana + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Sep 20, 2026, 4:43 PM EDT
Completed Not applicable Interventional Results available

The MOOD Study - External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) for the Treatment of Major Depressive Disorder (MDD)

NCT04279522
View directory record Official record
Conditions
MDD
Interventions
Relivion®DP- Active, Relivion®DP- Sham
Device
Lead sponsor
Neurolief Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
12
States / cities
La Jolla, California • Los Angeles, California • Miami Lakes, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Sep 20, 2026, 4:43 PM EDT
Completed Not applicable Interventional Results available

Pulsed Radiofrequency vs. Steroid Injections for Occipital Neuralgia

NCT01670825
View directory record Official record
Conditions
Occipital Neuralgia
Interventions
Pulsed radiofrequency, Corticosteroid injection, Local anethestic injection
Procedure · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Baltimore, Maryland • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Sep 20, 2026, 4:43 PM EDT
Not yet recruiting Not applicable Interventional

Optic Nerve Stimulation To Prevent Visual Deficits After Endoscopic Cranial Approaches

NCT06495580
View directory record Official record
Conditions
Optic Nerve Injuries, Sellar Tumor, Skull Base Neoplasms
Interventions
Optic Nerve Stimulation
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Sep 20, 2026, 4:43 PM EDT
Terminated No phase listed Interventional Results available

Feasibility of Bridge for Post-Operative Pain Management in Hip Arthroplasty

NCT05017701
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Bridge device, Sham device
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Sep 20, 2026, 4:43 PM EDT