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Conditions: Venous Leg Ulcer (VLU)
Interventions: Amnion-Intermediate-Chorion, Standard of Care (SOC); Other · Procedure
Lead sponsor: Cellution Biologics; Industry
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Rocky Mount, North Carolina

Conditions: Diabetic Foot Ulcers (DFUs), Diabetic Foot, Chronic Wounds
Interventions: Miro3D Wound Matrix, Standard of Care; Device · Other
Lead sponsor: Reprise Biomedical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 14
States / cities: Phoenix, Arizona • Coconut Creek, Florida • Coral Gables, Florida + 9 more

Conditions: Diabetic Foot Ulcer
Interventions: Derm-Maxx; Other
Lead sponsor: Capsicure, LLC; Network
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 11
States / cities: Athens, Alabama • Encino, California • Hollywood, Florida + 8 more

Conditions: Diabetic Foot Ulcer
Interventions: Dressing Application, Offloading; Procedure · Device
Lead sponsor: MiMedx Group, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 2
States / cities: Tulsa, Oklahoma • Roanoke, Virginia

Conditions: Diabetes, Peripheral Neuropathy, Diabetic Foot Ulcer
Interventions: Orpyx Sensory Insole System; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Diabetic Foot Ulcers
Interventions: AMNIOEXCEL, Standard of Care, Diabetic Foot Ulcers; Other
Lead sponsor: Integra LifeSciences Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 8
States / cities: Phoenix, Arizona • Castro Valley, California • Stockton, California + 5 more

Conditions: Diabetic Foot Ulcer
Interventions: Tenex TXB MicroTip Ultrasound system plus SOC, Standard of Care for diabetic foot ulcer; Device · Other
Lead sponsor: Tenex Health Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Mobile, Alabama • St. George, Utah

Conditions: Open Wound
Interventions: NeoThelium FT; Other
Lead sponsor: NuScience Medical Biologics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Hammond, Louisiana

Conditions: Diabetic Foot, Diabetic Foot Ulcer, Foot Ulcer, Diabetic, Foot Wound
Interventions: Lifestyle-focused Occupational Therapy Intervention, Education; Behavioral · Other
Lead sponsor: University of Southern California; Other
Eligibility: 21 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 3
States / cities: Downey, California • Los Angeles, California

Conditions: Diabetic Foot, Ulcer Foot
Interventions: Human split thickness skin allograft, Additional Outer Dressing Applicaiton, Offloading, Fibracol Wound Dressing; Other
Lead sponsor: Professional Education and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 5
States / cities: San Francisco, California • O'Fallon, Illinois • Youngstown, Ohio + 2 more

Conditions: Diabetic Foot Ulcer, Diabetic Foot, Foot Ulcer, Ulcer Foot, DFU
Interventions: SLAM + SOC, SOC; Other
Lead sponsor: Applied Biologics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Clinton Township, Michigan

Conditions: Diabetic Foot Ulcer, Diabetes Mellitus, Foot Ulcer, Foot Ulcer, Diabetic, Ulcer, Ulcer Foot, Ulcer, Leg, Ankle Ulcer
Interventions: Total Contact Soft Cast, Cam Boot; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Wounds
Interventions: After-care summary, Control group; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 2
States / cities: Ann Arbor, Michigan • Seattle, Washington

Conditions: Pressure Ulcer, Ulcer, Pressure, Pressure Wound, Pressure Area
Interventions: Standard of Care, XPURT + SOC; Other
Lead sponsor: Applied Biologics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Monroeville, Pennsylvania

Conditions: Heel Pressure Ulceration Prevention Strategies
Interventions: Pillow Condition 1, Pillow Condition 2, Heel Foam Pillow, Offloading Device A, Offloading Device B, Offloading Device C; Other · Device
Lead sponsor: DeRoyal Industries, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Diabetic Foot
Interventions: Removable cast walker, Irremovable cast walker; Device
Lead sponsor: University of Arizona; Other
Eligibility: 37 Years to 68 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Plantar Fasciitis, Chronic, Heel Pain Syndrome, Fat Pad Syndrome
Interventions: PopSole™ Offloading Device; Device
Lead sponsor: Jeffrey A. Gusenoff, MD; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Diabetic Foot Ulcers (DFUs), Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)
Interventions: Miro3D Wound Matrix, Standard of Care (SOC); Device · Other
Lead sponsor: Reprise Biomedical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 3
States / cities: Coconut Creek, Florida • Tamarac, Florida • New York, New York

Conditions: Diabetic Foot Ulcer
Interventions: Standard of Care: Moist Wound Therapy and Offloading, EpiFix plus Standard of Care; Other
Lead sponsor: MiMedx Group, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 20
States / cities: Birmingham, Alabama • Bakersfield, California • Castro Valley, California + 16 more

Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer, Ulcer Foot, Leg Ulcer
Interventions: Standard of Care-DFU, AmnioCore - DFU, Amnio Quad-Core - DFU, Standard of Care-VLU, Amnio Tri-Core - VLU, Amniocore Pro +; Other
Lead sponsor: Stability Biologics; Industry
Eligibility: 21 Years and older
Enrollment: 324 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Circleville, Ohio

Conditions: Venous Leg Ulcer (VLU), Venous Leg Ulcers, Venous Leg, Nonhealing Venous Leg Ulcer
Interventions: Intact Fish Skin Graft (IFSG) + Standard of Care, Standard of Care; Other
Lead sponsor: Kerecis Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Monroeville, Pennsylvania

Conditions: Diabetic Foot, Foot Ulcer; Diabetic
Interventions: Offloading, Dressing Application; Device · Procedure
Lead sponsor: Lower Extremity Institute for Research and Therapy; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2015
U.S. locations: 3
States / cities: Canfield, Ohio • Danville, Virginia • Troutville, Virginia

Conditions: Venous Leg Ulcer, Venous Leg, Diabetic Foot, Diabetic Foot Ulcer, Foot Ulcer, Diabetic, Ulcer Foot, Leg Ulcer, Ulcer Venous, Ulcer
Interventions: ACApatch™, caregraFT™, Standard of Care; Other
Lead sponsor: Tiger Biosciences, LLC.; Industry
Eligibility: 21 Years and older
Enrollment: 340 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Monroeville, Pennsylvania

Conditions: Diabetic Foot Ulcer, Ulcer Foot, Diabetic Foot
Interventions: Mirragen Advanced Wound Matrix, Fibracol; Device
Lead sponsor: ETS Wound Care, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 148 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 15
States / cities: Los Angeles, California • Pomona, California • San Francisco, California + 12 more

Search by objective public record fields.

Nonhealing Venous Leg Ulcers Treated With a Standard of Care (SoC) Alone or Standard of Care and Dehydrated Human Placenta Tissue (dHPT) With Crossover

Miro3D Wound Matrix for Treatment of Diabetic Foot Ulcers

Derm-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone

DHACM vs Other Commercially Available Treatments

Wearable Insoles for Recurrent Diabetic Ulcer Prevention

Phase IV Study to Evaluate the Efficacy of AMNIOEXCEL in Diabetic Foot Ulcers

Prospective, Multicenter, RCT of the Tenex Ultrasound System

Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Open Wounds

Evaluating a Lifestyle Intervention to Prevent Recurrence of Diabetic Foot Ulcers

Bioactive Split Thickness Skin Allograft Versus Standard of Care in the Treatment of Diabetic Foot Ulcers

Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care Versus Standard of Care

Total Contact Soft Cast in Diabetic Foot Ulcers

Does Use of a Wound After-care Summary Improve Patient Satisfaction and Time to Wound Healing?

A Multicenter, Prospective, Clinical Trial Evaluating a Single Layer Amniotic Membrane and Standard of Care Versus Matched Controls in the Management of Nonhealing Pressure Ulcers

Evaluation of Heel Offloading Devices for Reducing Heel Contact Pressures in Healthy Volunteers

The Association Between Unprotected Standing, Walking and Wound Healing in Diabetes

Validation of a Novel Foot Offloading Device

Miro3D Wound Matrix Study for Diabetic Foot Ulcers and Wound Healing

Trial of Dehydrated Human Amnion/Chorion Membrane (dHACM) In the Management of Diabetic Foot Ulcers

Modified Multi-Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of DFU and VLUs

Evaluating Intact Fish Skin Graft and Standard of Care Versus Standard of Care Alone in Nonhealing Venous Leg Ulcers

Study of Amniotic Membrane Graft in the Management of Diabetic Foot Ulcers

Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.

Bioresorbable Glass Fiber Matrix in the Treatment of Diabetic Foot Ulcers