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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Oleic Diet Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy Study of Stearidonic Acid (SDA) Soybean Oil-containing Foods on Red Blood Cell Fatty Acid Content

NCT01369550
View directory record Official record
Conditions
Healthy Volunteers, Markers of Cardiovascular Risk
Interventions
SDA soybean oil-containing foods, High-oleic sunflower oil containing foods, Eicosapentaenoic acid
Other
Lead sponsor
Monsanto Company, LLC
Industry
Eligibility
21 Years to 65 Years
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
2
States / cities
St. Petersburg, Florida • Addison, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 8, 2011 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of a Novel Method to Study in Vivo Fatty Acid Metabolism Using Stable Isotope Labeled Fatty Acids in Humans

NCT02312492
View directory record Official record
Conditions
Dyslipidemia
Interventions
Oleic Diet, Palmitic Diet, Stearic Diet
Other
Lead sponsor
Tufts University
Other
Eligibility
50 Years to 85 Years · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Differential Metabolism of Dietary Fatty Acids

NCT00059254
View directory record Official record
Conditions
Obesity, Diabetes, Hyperlipidemia
Interventions
Oleic acid (OA), Palmitic Acid (PA)
Dietary Supplement
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 35 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2005
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 11, 2017 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Canola Oil Multi-Centre Intervention Trial II

NCT02029833
View directory record Official record
Conditions
Cardiovascular Disease, Diabetes, Metabolic Syndrome
Interventions
Regular Canola Oil, High Oleic Canola Oil, Western Type Diet - Common Dietary Oils
Other
Lead sponsor
University of Manitoba
Other
Eligibility
20 Years to 65 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 16, 2023 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Soybean Oil Trial of cArdiovascular Risk

NCT02404207
View directory record Official record
Conditions
Cardiovascular Disease, Diabetes, Metabolic Syndrome
Interventions
Soybean oil, High-oleic soybean oil, High-oleic soybean oil + fully hydrogenated soybean oil, Palm olein + palm stearin
Other
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
30 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Saturated Fat Versus Monounsaturated Fat and Insulin Action

NCT01612234
View directory record Official record
Conditions
Obesity
Interventions
High palmitate or high oleate diet.
Dietary Supplement
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 40 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Dec 1, 2015 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Canola Oil Multi-center Intervention Trial II

NCT03054779
View directory record Official record
Conditions
Cardiovascular Disease, Metabolic Syndrome
Interventions
Canola Oil, High oleic acid canola oil, Western diet oil combination
Other
Lead sponsor
Penn State University
Other
Eligibility
20 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Role of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) on Inflammation and Lipids

NCT02670382
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
EPA, DHA, sunflower oil
Dietary Supplement
Lead sponsor
Tufts University
Other
Eligibility
50 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Phase 2 Interventional Results available

Fish Oil Supplementation, Nutrigenomics and Colorectal Cancer Prevention

NCT01661764
View directory record Official record
Conditions
Colorectal Adenomatous Polyps
Interventions
Eicosapentanoic acid and docosahexanoic acid, Oleic Acid
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
40 Years to 79 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 7, 2018 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Walnuts on Central Blood Pressure, Arterial Stiffness Indices, Lipoproteins, and Other CVD Risk Factors

NCT02210767
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Walnut Diet, Walnut Control Diet, Low ALA Diet
Other
Lead sponsor
Penn State University
Other
Eligibility
30 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 5, 2026, 2:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Fatty Acid Modulation of Brain Function in Older Adults

NCT06192407
View directory record Official record
Conditions
Aging
Interventions
High Oleic Acid Diet, High Palmitic Acid Diet
Dietary Supplement
Lead sponsor
University of Vermont
Other
Eligibility
65 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Avocado and Postprandial Responses

NCT06818032
View directory record Official record
Conditions
Healthy, Healthy Volunteer, Healthy Volunteers, Healthy Adult, Healthy Male and Female Subjects, Healthy Subjects, Healthy Volunteers Only, Healthy Non-smokers
Interventions
Negative control, Avocado, Fat and fiber addition
Other
Lead sponsor
University of Vermont Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Canola Oil Multicentre Intervention Trial (COMIT)

NCT01233778
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Canola Oil, High Oleic Acid + DHA Canola Oil, High Oleic Acid Canola Oil, Flax Oil, Safflower Oil
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
20 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Palmitoleic Acid on C-reactive Protein

NCT03625427
View directory record Official record
Conditions
Chronic Inflammation, Overweight
Interventions
Placebo, Palmitoleic acid, 500 mg (Dose 1), Palmitoleic acid, 1,000 mg (Dose 2)
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 30, 2022 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluation of the Safety and Biologic Effects of an Eicosapentaenoic (EPA)-Enriched Oil

NCT00988585
View directory record Official record
Conditions
Heart Disease
Interventions
EPA 600, EPA 1800, Olive Oil, DHA
Dietary Supplement
Lead sponsor
Cardiovascular Research Associates
Network
Eligibility
21 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 22, 2011 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Dietary Fatty Acids on Cardiovascular Disease Risk Indicators and Inflammation

NCT02145936
View directory record Official record
Conditions
Dyslipidemia
Interventions
diet
Other
Lead sponsor
Tufts University
Other
Eligibility
50 Years to 85 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 12, 2018 · Synced Sep 5, 2026, 2:19 AM EDT
Recruiting Not applicable Interventional

The Foods & Oil to Repair, Correct and Enhance Strength (FORCES) Study

NCT06361511
View directory record Official record
Conditions
Sarcopenia
Interventions
High Linoleic Acid Foods, High Oleic Acid Foods
Other
Lead sponsor
Ohio State University
Other
Eligibility
65 Years to 80 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 5, 2026, 2:19 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Fish Oil on Athlete's Executive Function

NCT04570995
View directory record Official record
Conditions
Brain Health, Brain Function, Brain Development
Interventions
Fish Oil, Safflower Oil
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Male only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 5, 2026, 2:19 AM EDT
Terminated Phase 1 Interventional

Placebo vs. Linoleic Acid Controlled Assessment of Treatment Efficacy in MS

NCT00638196
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Linoleic Acid/Oleic Acid
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 70 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 10, 2015 · Synced Sep 5, 2026, 2:19 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Omega-3 Fatty Acids for Smoking Cessation in Pregnancy

NCT04417595
View directory record Official record
Conditions
Preterm Labor, Tobacco Use Disorder
Interventions
Fish Oil (Containing Omega-3 Acids), Olive Oil
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
16 Years to 40 Years · Female only
Enrollment
237 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 5, 2026, 2:19 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Heat Therapy and Omega 3 on Cardio-Metabolic Health

NCT04051034
View directory record Official record
Conditions
Hypertension
Interventions
Omega 3, Placebo
Dietary Supplement · Other
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Sep 5, 2026, 2:19 AM EDT
Active, not recruiting Not applicable Interventional

Ritual Synbiotic+, a Dietary Supplement Designed to Impact Gastrointestinal Health, Mood, and Behavior in Women

NCT06834984
View directory record Official record
Conditions
Gastrointestinal Disease Symptoms
Interventions
Prebiotic, probiotic, postbiotic combination, Placebo
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
25 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 5, 2026, 2:19 AM EDT