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ClinicalTrials.gov public records Last synced Nov 7, 2026, 3:06 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 531 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Omega-3 fatty acid Clear all

Conditions: Bone Density, Bone Health, Fractures
Interventions: Vitamin D3 placebo, Fish oil placebo, Omega-3 fatty acids (fish oil), Vitamin D3; Dietary Supplement · Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 50 Years and older
Enrollment: 25,871 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Healthy
Interventions: Aspirin, omega-3 acid ethyl esters; Drug
Lead sponsor: Sanford Research; Other
Eligibility: 21 Years to 60 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007
U.S. locations: 1
States / cities: Sioux Falls, South Dakota

Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: Fish Oil Supplementation, Placebo Supplementation; Drug
Lead sponsor: Columbia University; Other
Eligibility: 12 Years to 18 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Cystic Fibrosis
Interventions: RELiZORB (immobilized lipase) cartridge, Impact Peptide 1.5; Device · Other
Lead sponsor: Alcresta Therapeutics, Inc.; Industry
Eligibility: 4 Years and older
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 10
States / cities: Hollywood, Florida • Boise, Idaho • Indianapolis, Indiana + 7 more

Conditions: Aging Problems
Interventions: Fish Oil, Soybean Oil; Dietary Supplement
Lead sponsor: University of Michigan; Other
Eligibility: 50 Years to 99 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Moderate Hypertriglyceridemia.
Interventions: Omega 3 fatty acid (Lovaza); Dietary Supplement
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Eldery People, Cognitive Decline, Memory Decline, DHA CNS Delivery
Interventions: LPC-EPA+DHA capsules containing omega-3 fatty acids EPA and DHA esterified to lysophosphatidylcholine (LPC-EPA+DHA)(Trade name: Lysoveta); Dietary Supplement
Lead sponsor: University of Cincinnati; Other
Eligibility: 55 Years to 82 Years
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Severe Hypertriglyceridemia
Interventions: placebo, omefas; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years and older
Enrollment: 399 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 30
States / cities: National City, California • Sacramento, California • Manchester, Connecticut + 25 more

Conditions: Inflammation
Interventions: Maqui berry/omeg-3 fatty acids, Placebos; Dietary Supplement
Lead sponsor: Arizona State University; Other
Eligibility: 50 Years to 85 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Alzheimer Disease
Interventions: Mediterranean Diet, Study Supplement, Low-fat Diet; Behavioral · Dietary Supplement
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 65 Years and older
Enrollment: 209 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Alzheimer's Disease
Interventions: icosapent ethyl (IPE), gel cap placebo; Drug · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years to 75 Years
Enrollment: 131 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Adenocarcinoma of the Prostate, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
Interventions: behavioral dietary intervention, omega-3 fatty acid, laboratory biomarker analysis; Behavioral · Dietary Supplement · Other
Lead sponsor: Jonsson Comprehensive Cancer Center; Other
Eligibility: 50 Years to 80 Years · Male only
Enrollment: 107 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)
Interventions: Epanova® (omega-3 carboxylic acids), corn oil control; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 13,078 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 229
States / cities: Birmingham, Alabama • Huntsville, Alabama • Muscle Shoals, Alabama + 183 more

Conditions: Myofacial Pain
Interventions: MyoRx Cream (6% Omega 3 Fatty Acid), Placebo cream, no Omega 3 fatty acid; Drug
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Tourette's Disorder
Interventions: Omega-3 Fatty Acids, Olive oil; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 6 Years to 18 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Omega-3 Fatty Acids, Pediatric Bipolar Disorder, Adolescent Bipolar Disorder, Magnetic Resonance Spectroscopy Imaging
Interventions: Omega-3 Fatty Acid, Placebo; Dietary Supplement · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 12 Years to 18 Years
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Cardiovascular Disease, Metabolic Syndrome
Interventions: Canola Oil, High oleic acid canola oil, Western diet oil combination; Other
Lead sponsor: Penn State University; Other
Eligibility: 20 Years to 65 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: Attention Deficit Hyperactivity Disorder (ADHD), Deficient Emotional Self-Regulation (DESR)
Interventions: ADHD Medication, Omega-3 Fatty Acids; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 55 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Bladder Cancer, Cystectomy, Chemotherapy
Interventions: Dietary and Exercise Intervention; Combination Product
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Cataract, Dry Eye Disease
Interventions: Omega-3 (Triglyceride form); Dietary Supplement
Lead sponsor: Physician Recommended Nutriceuticals; Industry
Eligibility: 30 Years to 90 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 2
States / cities: Lexington, Kentucky • Greenville, South Carolina

Conditions: Stress-related Changes in Inflammation
Interventions: omega-3 supplementation, Oral omega-3 fish oil placebo; Dietary Supplement
Lead sponsor: National Center for Complementary and Integrative Health (NCCIH); NIH
Eligibility: 18 Years to 40 Years
Enrollment: 68 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Bipolar Disorder, Involutional Depression, Mood Disorder
Interventions: Ethyl Eicosapentaenoic Acid, OmegaBrite; Drug
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: Not listed
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2002
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Mild Concussion, Brain Concussion, Cerebral Concussion
Interventions: Docosahexaenoic acid, Placebo; Dietary Supplement · Drug
Lead sponsor: East Carolina University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Greenville, North Carolina

Conditions: Brain Health, Brain Function, Brain Development
Interventions: Fish Oil, Safflower Oil; Dietary Supplement
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older · Male only
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Search by objective public record fields.

VITamin D and OmegA-3 TriaL: Interrelationship of Vitamin D and Vitamin K on Bone (VITAL)

Effects of Omacor and Aspirin on Platelet Function

Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study

Absorption and Safety With Sustained Use of RELiZORB Evaluation (ASSURE) Study

Explore Effects of Dietary Fish Oil in Human Skin

Lovaza Mechanisms of Action

Optimizing CNS DHA Delivery in Elderly Adults at Risk for Dementia

Epanova® for Lowering Very High Triglycerides

Maqui Berry Extract and Omega-3 Fatty Acids for Cytokine Reduction

Nutrition Interventions for Cognitive Enhancement

Brain Amyloid and Vascular Effects of Eicosapentaenoic Acid

Low-Fat Diet and Fish Oil in Men on Active Surveillance for Prostate Cancer

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia

Topical Application of MyoRx (Omega 3 Fatty Acids Containing) Cream

Omega-3 Fatty Acids in Tourette's Disorder

Omega 3 Fatty Acid Trial

Canola Oil Multi-center Intervention Trial II

Omega-3 Fatty Acid Supplementation to ADHD Pharmacotherapy in ADHD Adults With Deficient Emotional Self-Regulation Traits

A Home-based Lifestyle Intervention for Optimizing Surgical Outcomes Among Urinary Bladder Cancer Patients

The Influence of PRN Omega-3 Nutritional Supplement on Visual Acuity

Academic Stress and Proinflammatory Cytokines: Omega-3 Intervention

Omega-3 Fatty Acids in the Treatment of Bipolar Disorder: A Double-Blind, Placebo-Controlled Trial

High Dose Omega-3 Fatty Acids in the Treatment of Sport Related Concussions

Effect of Fish Oil on Athlete's Executive Function