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ClinicalTrials.gov public records Last synced Sep 23, 2026, 9:28 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Open Reduction and Internal Fixation Clear all
Not yet recruiting Not applicable Interventional

Study on Outcomes of Proximal Humerus Fractures

NCT07060664
View directory record Official record
Conditions
Proximal Humerus Fracture
Interventions
open reduction internal fixation, intramedullary nail, reverse total shoulder arthroplasty
Procedure
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 23, 2026, 9:28 PM EDT
Terminated Not applicable Interventional

Reamed Locked Plating - Metaphyseal Fractures of the Distal Femur and Tibia

NCT01553630
View directory record Official record
Conditions
Femoral Fractures, Tibial Fractures
Interventions
RIA bone graft, Surgery without bone graft
Procedure
Lead sponsor
Florida Orthopaedic Institute
Network
Eligibility
18 Years to 90 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 10, 2014 · Synced Sep 23, 2026, 9:28 PM EDT
Not yet recruiting Not applicable Interventional

Biodegradable Magnesium Screws for Unstable Ankle Fracture Surgery

NCT07693933
View directory record Official record
Conditions
Ankle Fractures, Syndesmotic Injury
Interventions
RemeOs Magnesium-Based Biodegradable Screw
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 23, 2026, 9:28 PM EDT
Not yet recruiting No phase listed Observational

Clinical Outcomes After Treatment of Distal Humerus Fractures With the LORRAINE 2.5/3.5 mm Distal Humerus System

NCT07774091
View directory record Official record
Conditions
Intra-Articular or Extra-Articular Distal Humerus Fracture, Distal Humerus Fracture
Interventions
LORRAINE 2.5/3.5 mm Distal Humerus System
Device
Lead sponsor
Bonebridge AG
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 23, 2026, 9:28 PM EDT
Completed Not applicable Interventional Results available

Using Alternative Implants for the Surgical Treatment of Hip Fractures (The FAITH Study)

NCT00761813
View directory record Official record
Conditions
Femoral Neck Fractures
Interventions
Open reduction internal fixation (ORIF) with single sliding hip screw, ORIF with multiple cancellous screws
Device
Lead sponsor
University of Minnesota
Other
Eligibility
50 Years and older
Enrollment
1,108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
32
States / cities
Birmingham, Alabama • Irvine, California • Orange, California + 28 more
Source: ClinicalTrials.gov public record
Updated Jan 4, 2018 · Synced Sep 23, 2026, 9:28 PM EDT
Withdrawn Not applicable Interventional

Auricular Acupuncture As Part Of A Multimodal Regimen After Distal Radius Open Reduction and Internal Fixation

NCT05974254
View directory record Official record
Conditions
Radius Fracture Distal, Pain, Postoperative
Interventions
Acupuncture
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Sep 23, 2026, 9:28 PM EDT
Completed Not applicable Interventional

Non-Operative Versus Operative Treatment for High-Energy Midshaft Clavicle Fractures

NCT00590850
View directory record Official record
Conditions
High Energy Midshaft Clavicle Fractures
Interventions
ORIF with Plate and Screws, Pin Fixation
Procedure
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years to 85 Years
Enrollment
412 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2023
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Sep 23, 2026, 9:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does Early Elbow Motion Improve Patient Outcomes After Surgically Treated Elbow Fractures?

NCT05980312
View directory record Official record
Conditions
Elbow Fracture, Range of Motion, Immobilization
Interventions
Splint Immobilization, Early Motion
Other
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 6, 2023 · Synced Sep 23, 2026, 9:28 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Impact of Early ADL Education on Outcomes Post DRF ORIF

NCT06251206
View directory record Official record
Conditions
Distal Radius Fractures
Interventions
ADL/Postoperative Instruction, Postoperative Instruction
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 110 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Washington, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 23, 2026, 9:28 PM EDT
Completed Not applicable Interventional

A Multicenter RCT to Investigate the Treatment of Double (Bilateral) Mandibular Fractures

NCT02341443
View directory record Official record
Conditions
Mandibular Fractures
Interventions
Implants
Procedure
Lead sponsor
AO Clinical Investigation and Publishing Documentation
Other
Eligibility
18 Years and older
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
New York, New York • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 18, 2020 · Synced Sep 23, 2026, 9:28 PM EDT
Terminated Not applicable Interventional

Diabetic Fibular Nail Study

NCT05204485
View directory record Official record
Conditions
Ankle Fractures
Interventions
Fibular intramedullary nail, Open reduction and internal fixation
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 85 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Sep 23, 2026, 9:28 PM EDT
Recruiting Not applicable Interventional

Cast or Operation for Medial Epicondyle Fracture Treatment in Children

NCT05131672
View directory record Official record
Conditions
Fracture Elbow
Interventions
open reduction and internal fixation (ORIF), cast immobilization
Procedure
Lead sponsor
Joseph Janicki
Other
Eligibility
7 Years to 17 Years
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2031
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 23, 2026, 9:28 PM EDT
Recruiting Phase 1 Interventional

Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau

NCT06639503
View directory record Official record
Conditions
Tibial Plateau Fractures
Interventions
Bupivacain
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 23, 2026, 9:28 PM EDT
Not listed No phase listed Observational

Treatment of Complex Pilon Fractures

NCT06089525
View directory record Official record
Conditions
Pilon Fracture
Interventions
Not listed
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 17, 2023 · Synced Sep 23, 2026, 9:28 PM EDT
Completed Not applicable Interventional Results available

Comparison of Operating Room Time Length With the Use of Virtual Surgical Planning Versus Conventional Treatment of Mandible Fractures

NCT04283981
View directory record Official record
Conditions
Mandibular Fractures
Interventions
Control group without use of VSP, Treatment Group with use of VSP
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 19, 2024 · Synced Sep 23, 2026, 9:28 PM EDT
Not listed Not applicable Interventional

Intraoperative Monitoring of Femoral Head Perfusion

NCT04110639
View directory record Official record
Conditions
Femoral Neck Fractures
Interventions
Intracranial pressure (ICP) monitor, Standard of Care
Device · Other
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
1 Year to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Sep 23, 2026, 9:28 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Application of Indocyanine Green Angiography for Closed Operative Calcaneus Fractures

NCT01693484
View directory record Official record
Conditions
Fractures, Comminuted, Surgical Wound Dehiscence, Necrosis
Interventions
ICG (Indocyanine Green)
Drug
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Sep 23, 2026, 9:28 PM EDT
Withdrawn Phase 4 Interventional

Duloxetine Tibial Plateau

NCT04639011
View directory record Official record
Conditions
Tibial Plateau Fracture, Pain, Postoperative
Interventions
Duloxetine, Placebo, Standard of care (SOC) for tibial plateau surgery
Drug · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts • Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2022 · Synced Sep 23, 2026, 9:28 PM EDT
Withdrawn Phase 1Phase 2 Interventional

A Study of Postsurgical Pain Control for Lower Extremity Fractures

NCT02214810
View directory record Official record
Conditions
Lower Extremity Fractures.
Interventions
Bupivacaine/Exparel
Drug
Lead sponsor
Broward Health
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Sep 23, 2026, 9:28 PM EDT
Completed Not applicable Interventional Results available

Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries

NCT00582998
View directory record Official record
Conditions
Fracture of Calcaneus, Pilon or Tibial Plateau
Interventions
Standard Wound Dressing, Vacuum Assisted Closure Device
Procedure · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Sep 23, 2026, 9:28 PM EDT
Completed Not applicable Interventional

RCT Determining Best Treatment for Geriatric Acetabular Fractures

NCT03419182
View directory record Official record
Conditions
Acetabular Fracture
Interventions
Open Reduction internal Fixation, Open Reduction Internal Fixation with Total Hip Arthroscopy
Procedure
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
60 Years to 100 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Sep 23, 2026, 9:28 PM EDT
Withdrawn No phase listed Observational

Operative Versus Nonoperative Treatment for Scapula Fractures

NCT00849771
View directory record Official record
Conditions
Scapula Fracture, Clavicle Fracture
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 12, 2015 · Synced Sep 23, 2026, 9:28 PM EDT
Terminated Not applicable Interventional Results available

Computer-Assisted Fixation of Trochanteric Femur Fractures

NCT04528459
View directory record Official record
Conditions
Hip Fractures
Interventions
Stryker© ADAPT™ platform, Traditional fluoroscopy
Device · Radiation
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2025 · Synced Sep 23, 2026, 9:28 PM EDT
Terminated No phase listed Observational

Safety Study of Treatment of Leg Fractures

NCT03881241
View directory record Official record
Conditions
Tibial Fractures
Interventions
Not listed
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Athens, Georgia • Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 9, 2020 · Synced Sep 23, 2026, 9:28 PM EDT