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ClinicalTrials.gov public records Last synced Oct 28, 2026, 12:59 PM EDT

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Showing 577–600 of 1,547 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Open Surgery Clear all
Completed Not applicable Interventional

Videoscopic Versus Open Inguinal Lymphadenectomy for Cancer

NCT01526486
View directory record Official record
Conditions
Melanoma, Merkel Cell Carcinoma, Squamous Cell Carcinoma, Penile Carcinoma, Urethral Carcinoma, Extramammary Paget's Disease, Scrotal Carcinoma, Anal Cancer, Vulvar Cancer, Skin Cancer, Lymphadenopathy
Interventions
Videoscopic procedure, Open, traditional approach
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 6, 2015 · Synced Oct 28, 2026, 12:59 PM EDT
Completed No phase listed Observational

Prospective Registry of Epicardial LV Leads Placed During Cardiac Surgery Procedures

NCT00288288
View directory record Official record
Conditions
Chronic Heart Failure
Interventions
Epicardial left ventricular lead placement, Transvenous left ventricular lead implant
Procedure
Lead sponsor
University of Kansas
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2012 · Synced Oct 28, 2026, 12:59 PM EDT
Completed Phase 1 Interventional

Thymus Transplantation With Immunosuppression

NCT00579709
View directory record Official record
Conditions
DiGeorge Syndrome, DiGeorge Anomaly, Complete DiGeorge Anomaly, Complete DiGeorge Syndrome
Interventions
Thymus Tissue for Transplantation
Biological
Lead sponsor
Sumitomo Pharma Switzerland GmbH
Industry
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Oct 28, 2026, 12:59 PM EDT
Not yet recruiting Phase 4 Interventional

MIRICURE: Mirikizumab With Curettage and Repair (Closure) for Perianal Fistulizing Crohn's Disease

NCT07782021
View directory record Official record
Conditions
Crohn's Disease, Perianal Fistula
Interventions
Mirikizumab, Fistula Tract Curettage and Closure
Drug · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Louis, Missouri • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 28, 2026, 12:59 PM EDT
Recruiting No phase listed Observational

Understanding the Acute Pain Phenotype in Patients Undergoing Surgery

NCT06466941
View directory record Official record
Conditions
Acute Pain, Chronic Post Operative Pain, Opioid Use
Interventions
regional anesthesia, no regional anesthesia, acute pain consultation, no acute pain consultation
Procedure · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 28, 2026, 12:59 PM EDT
Enrolling by invitation Phase 2Phase 3 Interventional

Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain

NCT06077422
View directory record Official record
Conditions
Pain, Postoperative, Opioid Use, Perioperative Complication, Heart Diseases
Interventions
bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 28, 2026, 12:59 PM EDT
Completed Early Phase 1 Interventional

Intraoperative Imaging of Breast Cancer With Indocyanine Green

NCT01796041
View directory record Official record
Conditions
Invasive Ductal Carcinoma, Invasive Lobular Carcinoma, Ductal Carcinoma
Interventions
Indocyanine Green
Drug
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Oct 28, 2026, 12:59 PM EDT
No Longer Available No phase listed Expanded access

Riociguat in Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

NCT01784562
View directory record Official record
Conditions
Hypertension, Pulmonary
Interventions
Adempas (Riociguat, BAY63-2521)
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 80 Years
U.S. locations
24
States / cities
Tucson, Arizona • La Jolla, California • Los Angeles, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2016 · Synced Oct 28, 2026, 12:59 PM EDT
Recruiting Not applicable Interventional

Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release

NCT05783245
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Perioperative/Postoperative Complications
Interventions
Polarcare Machine, Standard of care ice therapy
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 28, 2026, 12:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Feasibility of the IC-Flow Device for Fluorescent Perfusion Evaluation During Feasibility of the IC-Flow Device

NCT03860493
View directory record Official record
Conditions
Skin Flap Necrosis, Perfusion; Complications
Interventions
Perfusion evaluation with indocyanine green
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Oct 28, 2026, 12:59 PM EDT
Completed Phase 2 Interventional Results available

Study of Diclofenac Capsules to Treat Pain Following Surgery in Children Ages 6 to <17 Years of Age

NCT02424578
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Diclofenac Capsules low dose, Diclofenac Capsules high dose
Drug
Lead sponsor
Iroko Pharmaceuticals, LLC
Industry
Eligibility
6 Years to 16 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
5
States / cities
Sheffield, Alabama • Little Rock, Arkansas • Durham, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2017 · Synced Oct 28, 2026, 12:59 PM EDT
Terminated Not applicable Interventional Results available

An Open Label Trial to Decrease Signs and Symptoms of Orthostatic Hypotension Using Midodrine or Intravenous Fluid Bolus in Patients Following Total Hip Arthroplasty

NCT02154243
View directory record Official record
Conditions
Orthostatic Hypotension
Interventions
Midodrine, Intravenous fluid bolus
Drug · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 90 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced Oct 28, 2026, 12:59 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Assessing Superion Clinical Endpoints vs. Decompression

NCT03048955
View directory record Official record
Conditions
Spinal Stenosis, Lumbar Region With Neurogenic Claudication
Interventions
Superion® IDS, Direct decompression Surgery
Device · Procedure
Lead sponsor
VertiFlex, Incorporated
Industry
Eligibility
45 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
5
States / cities
Birmingham, Alabama • Carlsbad, California • Celebration, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2019 · Synced Oct 28, 2026, 12:59 PM EDT
Recruiting Not applicable Interventional

DBS of the SCC for the Treatment of Medically Refractory CLBP

NCT04085406
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Deep Brain Stimulation of the Subgenus Cingulate Cortex
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
40 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Oct 28, 2026, 12:59 PM EDT
Terminated Early Phase 1 Interventional

Phase 0 Biodistribution of Novel Imaging for Resectable Pancreatic Cancer

NCT01962909
View directory record Official record
Conditions
Pancreatic Ductal Adenocarcinoma
Interventions
PTP-01
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 18, 2016 · Synced Oct 28, 2026, 12:59 PM EDT
Completed Not applicable Interventional

"Embolization Before Ablation of Renal Cell Carcinoma (EMBARC)"

NCT05410509
View directory record Official record
Conditions
Renal Cell Carcinoma (RCC)
Interventions
Trans-arterial embolization (TAE)
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Birmingham, Alabama • Stanford, California • Rochester, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 28, 2026, 12:59 PM EDT
Enrolling by invitation No phase listed Observational

CTICU Device Study CRUISE

NCT06828432
View directory record Official record
Conditions
Open Heart Surgery
Interventions
CRUISE CTICU CareTaker Vitalstream Device, CRUISE CTICU CNAP Device, CRUISE CTICU Edwards Clearsight Device
Device
Lead sponsor
Hernando Gomez
Other
Eligibility
18 Years to 105 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 28, 2026, 12:59 PM EDT
Withdrawn No phase listed Observational

Omega-3 Fatty Acid Status in Morbid Obesity Before and After Surgical Treatment

NCT00558532
View directory record Official record
Conditions
Morbid Obesity, Cardiovascular Disease, Fatty Acid Levels
Interventions
Bariatric Surgery
Procedure
Lead sponsor
University of Cincinnati
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 13, 2016 · Synced Oct 28, 2026, 12:59 PM EDT
Suspended Not applicable Interventional

Operative Procedures Vs. Endovascular Neurosurgery for Untreated Pseudotumor Trial

NCT02513914
View directory record Official record
Conditions
Pseudotumor Cerebri, Idiopathic Intracranial Hypertension (IIH)
Interventions
Dural Venous Sinus Stenting, Cerebrospinal Fluid Shunting
Device
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Phoenix, Arizona • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Oct 28, 2026, 12:59 PM EDT
Recruiting Not applicable Interventional

TAVR vs SAVR in Severe Bicuspid Aortic Stenosis

NCT07413965
View directory record Official record
Conditions
Bicuspid Aortic Valve Disease
Interventions
Transcatheter Aortic Valve Replacement, the open chest surgery to replace the aortic valve
Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
50 Years and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2040
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 28, 2026, 12:59 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With Depression

NCT05966532
View directory record Official record
Conditions
Major Depressive Disorder (MDD), Healthy Adult Volunteer
Interventions
Hot Cognitive Task, Cold cognitive tasks, Structural magnetic resonance imaging (sMRI), Magnetoencephalography imaging (MEG), four self-report forms per the requirement of the NIH Common Data Elements project, Four self-report measures to assess interpersonal functioning, Clinical assessments, ATHF
Behavioral · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
276 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
Arlington, Texas • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 28, 2026, 12:59 PM EDT
Completed No phase listed Observational

A Quality Initiative to Improve Glycemic Control in Diabetic and Non-Diabetic Insulin Study

NCT01916733
View directory record Official record
Conditions
Glycemic Control, Surgical Site Infections, Cardiac Complications, Length of Stay, Cost
Interventions
standard insulin protocol post-op (continuous IV insulin)
Drug
Lead sponsor
University of Vermont Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 25, 2016 · Synced Oct 28, 2026, 12:59 PM EDT
Completed No phase listed Observational

Age and Endothelial Progenitor Cell Mobilization

NCT00585949
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Percutaneous Coronary Angioplasty, Angiography
Procedure
Lead sponsor
Emory University
Other
Eligibility
Not listed
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Oct 28, 2026, 12:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of Human Laryngeal Evoked Brainstem Potentials

NCT02803359
View directory record Official record
Conditions
Thyroidectomy
Interventions
Placement of a needle electrode through the thyrohyoid membrane into the submucosal space within the false vocal fold
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2020 · Synced Oct 28, 2026, 12:59 PM EDT