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Showing 1–24 of 309 matching trials from the live ClinicalTrials.gov search.
Conditions
Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe, Criminal Behavior
Interventions
BNI Chatbot, OUD Education & Treatment Resources
Behavioral
Lead sponsor
Center for Progressive Recovery, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Opioid Consumption, Postoperative, Pain After Surgery, Opioid Dependency
Interventions
Opioid tapering with CBT and education, Opioid tapering with education alone
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Philadephia, Pennsylvania
Conditions
Pain, Postoperative, Medication Adherence, Opioid Use, Knowledge, Attitudes, Practice, Risk Reduction Behavior
Interventions
Educational Intervention, Nudge
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 99 Years
Enrollment
712 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty (Postoperative Pain)
Interventions
Transcranial Direct Current Stimulation, Cognitive-Behavioral (CB) intervention
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 90 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Phase 3 Interventional Results available

Buprenorphine Group Medical Visits in Primary Care

NCT02526212
Conditions
Opioid-Related Disorders
Interventions
G-BMT, Treatment as usual, Buprenorphine
Behavioral · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Low Back Pain, Opioid Use
Interventions
Meditation, Usual care
Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
La Jolla, California • Salt Lake City, Utah
Recruiting Not applicable Interventional Accepts healthy volunteers

Craving & Decision-Making

NCT06440577
Conditions
Decision Making
Interventions
Audio-visual stimuli (Neutral-Relaxing), Audio-visual stimuli (Drug), Audio-visual stimuli (Non-Food), Audio-visual stimuli (Food)
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Piscataway, New Jersey
Conditions
Orthopedic Surgery, Neurosurgery, Surgery, Opioid Use, Opioid Misuse
Interventions
Medication Disposal Packet
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 99 Years
Enrollment
657 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nudges and Incentives to Enhance the Opioid Treatment Workforce

NCT03834025
Conditions
Opioid Abuse (Disorder)
Interventions
Phase 1 Condition 1, Phase 1 Condition 2, Phase 1 Condition 3, Phase 1 Condition 4, Phase 2 Condition 1, Phase 2 Condition 2, Phase 2 Condition 3
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Opioid Overdose
Interventions
Enhanced Overdose Education (EOE), Standard education
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
21 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Hartford, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treatment, Pain, and Opioids

NCT05363176
Conditions
Chronic Pain
Interventions
Cognitive-Behavioral Therapy for Treatment Seeking, Pain treatment education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Canandaigua, New York
Conditions
Cognitive Coping, Cancer
Interventions
Cancer Pain 101, Pharmacotherapy Informational Packet
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Opioid Use Disorder
Interventions
Gender-specific digital intervention (GSDI), Treatment as usual
Behavioral · Other
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Belmont, Massachusetts
Conditions
Pain, Postoperative, Opioid Use
Interventions
Perioperative Pain Management Education and Counseling
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
14 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Surgical Procedure, Unspecified, Orthopedic Disorder
Interventions
Standardized instructions, Conventional instructions
Other
Lead sponsor
Giorgio Veneziano
Other
Eligibility
Up to 20 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Opioid Use Disorder, Chronic Pain
Interventions
Steps 2 Change (S2C), Control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
West Haven, Connecticut
Conditions
Stigma, Social, Opioid Use, Opioid-use Disorder, Substance Use Disorders
Interventions
Intrapersonal Stigma Reduction, Interpersonal Stigma Reduction
Other
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Memphis, Tennessee
Not yet recruiting Not applicable Interventional

MedSMA℞T Mobile ED

NCT06848504
Conditions
Opiate-Related Disorders, Opiate Use Disorder, Opioid
Interventions
MedSMA℞T Mobile
Behavioral
Lead sponsor
Olufunmilola Abraham
Other
Eligibility
12 Years and older
Enrollment
244 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
3
States / cities
Rockford, Illinois • Madison, Wisconsin
Completed Not applicable Interventional Results available

Opioid Use Disorder in the Emergency Department: CTN 0069

NCT03023930
Conditions
Opioid Use Disorder
Interventions
Standard Dissemination Practice, Implementation Facilitation (IF)
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
1,731 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
5
States / cities
Baltimore, Maryland • New York, New York • Cincinnati, Ohio + 1 more
Conditions
HIV Disease, Chronic Pain
Interventions
Communication Strategy, Standard of Care
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Facilitating MAT Acceptance & Implementation in Problem Solving & Felony Courts

NCT03229447
Conditions
Improving Treatment for Opioid Use Disorder in Courts
Interventions
eLearning Modules, Change Team Intervention
Behavioral
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Terminated Not applicable Interventional Accepts healthy volunteers

BUPrenorphine Facilitated Access and Supportive Treatment --AIM 3

NCT02902835
Conditions
Opioid-related Disorders
Interventions
BUP_FAST, Referral to treatment
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Completed Not applicable Interventional Results available

De-Implementing Opioids for Dental Extractions

NCT03584789
Conditions
Tooth Extraction
Interventions
Clinical Decision Support, Patient education
Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
16 Years and older
Enrollment
5,722 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Bloomington, Minnesota
Conditions
Mood Disorders, Anxiety, Depressive Symptoms, Depression, Anxiety Disorders, Anxiety Depression
Interventions
-RxWell
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Monroeville, Pennsylvania • Pittsburgh, Pennsylvania