- Conditions
- Opioid-Related Disorders
- Interventions
- Buprenorphine
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years to 65 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1988 – 2006
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
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Showing 1–24
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Opioid Use Disorder
- Interventions
- Computerized Anxiety Sensitivity Treatment
- Behavioral
- Lead sponsor
- Southeast Louisiana Veterans Health Care System
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- New Orleans, Louisiana
- Conditions
- Opioid Use Disorder, Injection Related Infections, Stimulant Use Disorder
- Interventions
- Integrated Infectious Diseases and Substance Use Disorder Clinic (IC)
- Behavioral
- Lead sponsor
- Elana Rosenthal
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 304 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 4
- States / cities
- Washington D.C., District of Columbia • Atlanta, Georgia • Baltimore, Maryland + 1 more
- Conditions
- Opioid Use Disorder
- Interventions
- ED-LINC
- Other
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Opioid Dependence
- Interventions
- Suboxone Sublingual Film, Zubsolv sublingual tablets
- Drug
- Lead sponsor
- Indivior Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013
- U.S. locations
- 1
- States / cities
- St. Petersburg, Florida
- Conditions
- Opiate Antagonist Overdose, Opioid-Related Disorders
- Interventions
- Naloxone Auto-Injector
- Behavioral
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 395 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Opiate-Related Disorders, Opiate Use Disorder, Opioid
- Interventions
- MedSMA℞T Mobile
- Behavioral
- Lead sponsor
- Olufunmilola Abraham
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 244 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 3
- States / cities
- Rockford, Illinois • Madison, Wisconsin
- Conditions
- Compliance, Chronic Pain
- Interventions
- acetazolamide, Quinine, Riboflavin
- Drug
- Lead sponsor
- Georgetown University
- Other
- Eligibility
- 18 Years to 50 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Opioid Agonist Treatment, Alcohol Use Disorder, Opioid Use Disorder
- Interventions
- Digital Contingency Management Intervention Arm, Digital Wellness Arm
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 19 Years to 63 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Opioid Abuse
- Interventions
- Overdose Notification
- Behavioral
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 61 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Opioid Use
- Interventions
- Life Care Specialist (LCS) Intervention, Clinical Coordination with Referrals, Pilot Study of Pain Management Strategies
- Behavioral · Other
- Lead sponsor
- Emory University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 333 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Opioid-use Disorder, Opioid Dependence, Opioid Overdose, Opioid Use, Substance Use Disorders
- Interventions
- Buprenorphine, Naloxone Drug Combination, Individual Counseling, Peer Recovery Support Services, Support Group, Referral to Medication Management, Assertive Outreach
- Drug · Behavioral
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2030
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Opioid-Related Disorders, Pain Management, Pain Management and Care, Advanced Cancer, Advanced Cancers
- Interventions
- Psilocybin
- Drug
- Lead sponsor
- Yvan Beaussant, MD, MSci
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Opiate Overdose, Opioid-Related Disorders, Narcotic-Related Disorders, Substance-related Disorders, Chemically-Induced Disorders, Mental Disorders
- Interventions
- Machine Learning-Based Clinical Decision Support: Overdose Prevention Alert (OPA) Intervention
- Behavioral
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 674 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Pain, Drug Overdose, Opioid Use Disorders
- Interventions
- Motivational intervention, Psycho-educational control, Long-term opioid therapy informed consent
- Behavioral · Other
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 299 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2021
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Opioid-use Disorder
- Interventions
- reSET-O app
- Device
- Lead sponsor
- Milton S. Hershey Medical Center
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Harrisburg, Pennsylvania
- Conditions
- Opioid-use Disorder, HIV Prevention Program
- Interventions
- Contingency Management with stepped care to PrEP adherence and support services (CoMPASS)
- Behavioral
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 526 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2027
- U.S. locations
- 6
- States / cities
- Bridgeport, Connecticut • Danbury, Connecticut • New Haven, Connecticut + 1 more
- Conditions
- Persistent Post-surgical Pain, Acceptance and Commitment Therapy, Substance Use Disorder
- Interventions
- ACT (Acceptance and Commitment Therapy)
- Behavioral
- Lead sponsor
- Barbara A Rakel
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- HIV Infections
- Interventions
- Methadone hydrochloride, Zidovudine
- Drug
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Eligibility
- 18 Years and older
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Opioid Use, Opioid-use Disorder
- Interventions
- Case Management and Peer Recovery, Naloxone-Only
- Behavioral
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,500 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2026
- U.S. locations
- 5
- States / cities
- Chicago, Illinois • Murphysboro, Illinois • Ottawa, Illinois + 2 more
- Conditions
- Opioid Use Disorder
- Interventions
- Exablate Model 4000 Type 2.0/2.1
- Device
- Lead sponsor
- West Virginia University
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Morgantown, West Virginia
- Conditions
- Chronic Pain
- Interventions
- Pregabalin, Placebo
- Drug
- Lead sponsor
- Georgetown University
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Opioid-Related Disorders
- Interventions
- OD prevention/response training, OD prevention/response training + PI mobile application
- Behavioral
- Lead sponsor
- National Development and Research Institutes, Inc.
- Other
- Eligibility
- 18 Years to 29 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Opiate Dependence, Sexually Transmitted Diseases, HIV
- Interventions
- Acceptance and Commitment Therapy, Information Motivation Behavioral Model
- Behavioral
- Lead sponsor
- Rhode Island Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island