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ClinicalTrials.gov public records Last synced Oct 17, 2026, 4:43 PM EDT

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Showing 73–96 of 124 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Opt-out Clear all
Not yet recruiting Not applicable Interventional

Implementation of an Opt-Out Testing and Rapid Diagnostic Strategy for Syphilis and HIV in Pregnant Patients Presenting to the Emergency Department

NCT07525076
View directory record Official record
Conditions
HIV Infections, Syphilis Infection
Interventions
Chembio HIV/Syphilis rapid Point of Care (POC) test, Laboratory-based HIV and syphilis testing
Diagnostic Test
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
1,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 17, 2026, 4:43 PM EDT
Recruiting No phase listed Observational

Biomarkers of Resiliency In Childhood Cancer Surgery

NCT06674811
View directory record Official record
Conditions
Pediatric Cancer, Neuroblastoma, Sarcoma, Wilms Tumor and Other Childhood Kidney Tumors, Childhood Soft Tissue Sarcoma, Childhood Bone Sarcoma, Childhood Malignant Intestinal Neoplasm, Childhood Malignant Liver Neoplasm, Childhood Malignant Lung Neoplasm, Childhood Malignant Ovarian Neoplasm, Childhood Malignant Pleural Neoplasm, Childhood Neuroblastic Tumor, Childhood Sarcoma
Interventions
Wearing Smartwatch, Patient Report Outcomes, Blood Draw, Clinical Data Review
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
3 Years to 25 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 17, 2026, 4:43 PM EDT
Completed Phase 3 Interventional Results available

Low Dose Oral Methotrexate in Pediatric Crohn's Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy

NCT02772965
View directory record Official record
Conditions
Pediatric Crohn's Disease
Interventions
Methotrexate, Sugar pill (placebo)
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
Up to 20 Years
Enrollment
306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
32
States / cities
Birmingham, Alabama • Alto, California • New Haven, Connecticut + 27 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Oct 17, 2026, 4:43 PM EDT
Terminated Not applicable Interventional

The Comparison of Semiconductor Embedded Therapeutic Arm Sleeves for the Treatment of ECRB Tendinopathy

NCT06846593
View directory record Official record
Conditions
ECRB Tendinopathy
Interventions
Semiconductor Embedded Therapeutic Arm Sleeves, Placebo Arm Sleeves, Platelet-Rich Plasma with Adipose Stem Cell (PRP+ASC) Injections
Device · Other
Lead sponsor
INCREDIWEAR HOLDINGS, INC.
Industry
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 17, 2026, 4:43 PM EDT
Not yet recruiting Not applicable Interventional

Opt-In Early Pilot Study

NCT06908187
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Opt-In Early Latinx intervention, Opt-In Early Rural Intervention
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
15 Months and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Hartford, Connecticut • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 17, 2026, 4:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Default Option for Health: Improving Nutrition Within the Financial and Geographic Constraints of Food Insecurity

NCT04186533
View directory record Official record
Conditions
Food Selection, Obesity
Interventions
Default Option, Nutrition Education
Behavioral
Lead sponsor
University at Albany
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Dec 4, 2019 · Synced Oct 17, 2026, 4:43 PM EDT
Completed Not applicable Interventional

Default Genetics Referrals for Young-Onset Colorectal Cancer

NCT05018156
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Default Genetics Referral Process
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years to 49 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 19, 2022 · Synced Oct 17, 2026, 4:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Boricua Youth Study COVID-19 Coping Intervention Study

NCT05444881
View directory record Official record
Conditions
Psychological Stress, Depression, Anxiety
Interventions
Mindfulness-based Intervention (Headspace TM)
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
Not listed
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 17, 2026, 4:43 PM EDT
Completed No phase listed Observational

Prematurity-Related Ventilatory Control

NCT03464396
View directory record Official record
Conditions
Respiratory Control in Premature Infants
Interventions
Bedside Physiology study, Carotid Body Function Test, Room Air Challenge, Hypoxia Challenge Test, Effects of Nasal Cannula Flow, Magnetic Resonance Imaging, Echocardiogram, Blood Sample
Other · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
1 Day to 28 Days
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Oct 17, 2026, 4:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

BP PAL - Hypertension Chat Bot Pilot

NCT05571410
View directory record Official record
Conditions
Hypertension
Interventions
HTN Chat bot
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 25, 2024 · Synced Oct 17, 2026, 4:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Screen Smart: Using Digital Health to Improve HIV Screening and Prevention

NCT06003192
View directory record Official record
Conditions
HIV Infections
Interventions
Universal Opt-out HIV Screening
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
15 Years to 21 Years
Enrollment
63,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
4
States / cities
Columbus, Ohio • Philadelphia, Pennsylvania • Salt Lake City, Utah + 1 more
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 17, 2026, 4:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Arizona CEAL: Linking Social Care With Healthcare Systems to Address SDOH

NCT07799961
View directory record Official record
Conditions
Social Determinants of Health (SDOH), Hypertension, Diabetes Mellitus, Hypercholesterolaemia
Interventions
Community Health Worker intervention, Usual Care
Other
Lead sponsor
Sairam Parthasarathy
Other
Eligibility
18 Years and older
Enrollment
740 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 17, 2026, 4:43 PM EDT
Completed Not applicable Interventional

Machine-Generated Mortality Estimates and Nudges to Promote Advance Care Planning Discussion Among Cancer Patients

NCT03984773
View directory record Official record
Conditions
Oncology
Interventions
Nudge
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 17, 2026, 4:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Text Message Nudges for COVID-19 Vaccination

NCT05037201
View directory record Official record
Conditions
Covid19
Interventions
Text message
Behavioral
Lead sponsor
Mitesh Patel
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Oct 17, 2026, 4:43 PM EDT
Completed Not applicable Interventional Results available

Telephone-Based Program to Promote Inhaled Corticosteroid Adherence Among Individuals With Asthma

NCT00414817
View directory record Official record
Conditions
Asthma
Interventions
Automated Phone-Based Refill Reminders
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
14,064 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Honolulu, Hawaii • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Oct 17, 2026, 4:43 PM EDT
Withdrawn No phase listed Observational

Biopsy Collection for Men Undergoing Brachytherapy for Prostate Cancer

NCT04243473
View directory record Official record
Conditions
Prostate Cancer
Interventions
Not listed
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years to 100 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 17, 2026, 4:43 PM EDT
Recruiting No phase listed Observational

Navigator-Assisted Hypofractionation (NAVAH) on Radiation Therapy Completion in Breast Cancer and Prostate Cancer

NCT07014618
View directory record Official record
Conditions
Breast Cancer, Prostate Cancer
Interventions
Pre & Post Surveys, Opt Out of Questionnaire
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 17, 2026, 4:43 PM EDT
Completed Not applicable Interventional

Caria: Digital Intervention for Menopause Symptom

NCT04882982
View directory record Official record
Conditions
Menopause, Hot Flashes
Interventions
Caria app, Menopause Education
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Oct 17, 2026, 4:43 PM EDT
Active, not recruiting Not applicable Interventional

Comparing an Opt-out to an opt-in Approach for Smoking Cessation in VA Primary Care Clinics

NCT03477435
View directory record Official record
Conditions
Tobacco Use
Interventions
Staff training and academic detailing
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
1,365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 17, 2026, 4:43 PM EDT
Completed No phase listed Observational

HIV Jail POC-AgAB Testings

NCT04296331
View directory record Official record
Conditions
HIV/AIDS
Interventions
POC, Ag/Ab, POC + Ag/Ab
Diagnostic Test
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
6,613 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Oct 17, 2026, 4:43 PM EDT
Completed Not applicable Interventional

Improving Diagnosis and Clinical Management of Familial Hypercholesterolemia Through Integrated Machine Learning, Implementation Science, and Behavioral Economics

NCT05746247
View directory record Official record
Conditions
Familial Hypercholesterolemia
Interventions
Testing centralized referral mechanism for PCPs, Inviting patients to complete a telehealth appointment with a lipid specialist for an FH evaluation
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 17, 2026, 4:43 PM EDT
Completed Not applicable Interventional Results available

Evaluating the Efficacy of Pediatric Lipid Screening Alerts

NCT04118348
View directory record Official record
Conditions
Hypercholesterolemia, Hypercholesterolemia, Familial, Hypercholesteremia in Children, Hyperlipidemia in Children
Interventions
Best Practice Alert, Health Maintenance Topic
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
9 Years to 11 Years
Enrollment
13,340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 17, 2026, 4:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining Choice Architecture for Genetic Testing Decisions

NCT04372888
View directory record Official record
Conditions
Decision Making
Interventions
choice decision frame, opt-in decision frame, opt-out decision frame, enhanced choice (context) decision frame, enhanced choice (norms) decision frame, enhanced choice (affect) decision frame
Behavioral
Lead sponsor
Boston College
Other
Eligibility
18 Years to 64 Years
Enrollment
1,012 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Oct 17, 2026, 4:43 PM EDT
Completed Not applicable Interventional

Incentivizing Buprenorphine-Naloxone Initiation in Emergency Departments

NCT03821103
View directory record Official record
Conditions
Opioid Use
Interventions
Training, Behavioral economic enhanced arm
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Oct 17, 2026, 4:43 PM EDT