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ClinicalTrials.gov public records Last synced Nov 12, 2026, 12:14 AM EST

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Showing 1–24 of 154 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Oral Hygiene Clear all

Conditions: Peri-implant Mucositis, Peri-Implantitis
Interventions: Induction of experimental peri-implant mucositis, Resolution of experimental peri-implant mucositis; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Autism
Interventions: Procedure alteration and occupational therapy; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 5 Years to 12 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Post Extubation Dysphagia
Interventions: Ice chips; Other
Lead sponsor: Atlantic Health System; Other
Eligibility: 18 Years to 100 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Morristown, New Jersey

Conditions: Dental Caries
Interventions: Toothpaste & Telephone Support; Behavioral
Lead sponsor: Advantage Dental Services, LLC; Industry
Eligibility: 6 Months to 20 Years
Enrollment: 21,731 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Redmond, Oregon

Conditions: Pain, Thirst, Anxiety, Satisfaction
Interventions: mouth care, pain intervention; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Gingivitis, Supragingival Plaque
Interventions: Brushing and Flossing of teeth, Brushing Only; Device · Other
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Rib Fracture, Rib Fracture Multiple, Trauma, Trauma Chest, Trauma Injury, Trauma, Multiple
Interventions: RibFx Orthosis Belt; Device
Lead sponsor: University of Vermont Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Inflammation, Periodontitis
Interventions: Sonicare/Elite-Flexcare Toothbrush, Manual Toothbrush; Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 75 Years
Enrollment: 175 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Microstomia
Interventions: Splint; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 2 Years to 99 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Radiation-Induced Xerostomia, Head and Neck Cancer, Radiation Toxicity, Oral Complications of Chemotherapy and Head/Neck Radiation
Interventions: Standard Oral Hygiene, Standard Oral Hygiene + True Acupuncture, Standard Oral Hygiene + Sham Acupuncture; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 258 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2022
U.S. locations: 36
States / cities: Burbank, California • San Francisco, California • San Jose, California + 26 more

Conditions: Gingivitis
Interventions: AirFloss + BreathRx, AirFloss + Listerine, Dental Floss, Manual Toothbrush; Device
Lead sponsor: Philips Oral Healthcare; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 290 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Oral Hygiene
Interventions: Motivational Interviewing; Behavioral
Lead sponsor: San Diego State University; Other
Eligibility: 14 Years to 19 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Vista, California

Conditions: Motivational Interviewing, BMI, OHI
Interventions: BMI; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Cancer Survivors, Neoplasms
Interventions: Eat, Play, Sleep; Behavioral
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Head and Neck Cancer, Oral Mucositis
Interventions: Standard of Care Oral Hygiene, Oral mucosal deterging and dental prophylaxis; Other · Procedure
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Cardiovascular Disease, Coronary Heart Disease, Myocardial Infarction, Cerebrovascular Accident
Interventions: Periodontal Treatment: SRP, Referral; Procedure
Lead sponsor: University at Buffalo; Other
Eligibility: Up to 75 Years
Enrollment: 303 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Health Knowledge, Attitudes, Practices
Interventions: Science Tooth Fairy Narrative, Cavities vs. Toothpaste, book by Didi Dragon; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: Not listed
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Primary Total Hip Arthroplasty, Primary Total Knee Arthroplasty
Interventions: Diphenhydramine (Benadryl), Melatonin, Sleep Hygiene Education; Drug · Dietary Supplement · Behavioral
Lead sponsor: James A. Keeney; Other
Eligibility: 18 Years and older
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Gingival Inflammation
Interventions: Flossing technique; Other
Lead sponsor: Tufts University; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Gingivitis
Interventions: Abstinence of oral hygiene on select teeth; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 35 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Dental Anxiety in Children, Feasibility Studies, Comfort
Interventions: Modified Bottom-to-Bottom Comfort Position; Other
Lead sponsor: Children's Hospital Colorado; Other
Eligibility: 12 Months to 5 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Oral Malodor
Interventions: Brush / Espresso Mild Prototype, Brush / Espresso Intense Prototype, Brush / Fresh Breath Oral Rinse, Brush / Hydroalcohol; Other
Lead sponsor: Johnson & Johnson Consumer and Personal Products Worldwide; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 166 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Lung Cancer, Mucositis Oral, Dehydration, Head and Neck Cancer
Interventions: Symptom Management Education and Nurse Coaching, Drinks Diary; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Sleep Problem, Behavior, Child
Interventions: Sleep Health in Preschoolers (SHIP), Family Check-Up (FCU), Oral Health, Child Safety, and Environmental Health Intervention (Active Control); Behavioral
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 18 Months to 48 Months
Enrollment: 305 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 2
States / cities: Denver, Colorado • Boston, Massachusetts

Search by objective public record fields.

Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty

Program to Improve Dental Care: Children With ASD

Functional Oral-Pharyngeal Rehabilitation of Patients With Dysphagia Using Ice-chips, a Prospective Randomized Study

Everybody Brush: A Community-wide Toothpaste Distribution Campaign

ICU Patient and Family Comfort Study

Evaluation of the Efficacy and Safety of a Loop Stretchable Dental Floss

Orthosis of Acute Traumatic Rib Fractures Via RibFx Belt for Pain Alleviation and Improved Pulmonary Function

Salivary Inflammatory Biomarkers: Predictors & Comparative Effects of Sonicare/Elite-Flexcare in Stages of Perio Disease

Efficacy of 3D-Printed Mouth Splints

Trial of Acupuncture for Radiation-Induced Xerostomia in Head and Neck Cancer

Efficacy and Safety Study of Interproximal Cleaning Modalities on Oral Health

Oral Hygiene Intervention for Adolescents

Brief Motivational Interviewing (BMI)

Eat, Play, Sleep: A Text Message Approach to Promoting Health Behaviors for Cancer Survivors and Their Caregivers

Commensal Oral Microbiota in Head and Neck Cancer

Periodontitis and Cardiovascular Events or "PAVE"

The Science Tooth Fairy: A Randomized Trial of a Storytelling-Based Educational Intervention to Promote Primary Tooth Donation in a Pediatric Setting

Total Joint Arthroplasty and Sleep

The Effect of Instructed Dental Flossing on Interdental Gingival Bleeding: A Randomized Controlled Clinical Trial

Variation in Gingival Inflammatory Responses

Feasibility of a Modified Dental Comfort Position for Pediatric Patients Receiving Dental Exams

Four-Week Oral Malodor and Clinical Safety for a Concentrated Cosmetic Mouthwash

Feasibility Study of a Nurse Intervention to Impact Mucositis Severity and Prevent Dehydration

Parents Advancing Toddler Health