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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:18 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 39 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Oral PCA Clear all

Conditions: Obesity, Morbid, Surgery, Bariatric Surgery Candidate
Interventions: Neurontin, Dilaudid Injectable Product, Marcaine Injectable Product, Oxycodone Hydrochloride, Hycet 7.5Mg-325Mg/15Ml Solution, Zofran Injection, Scopolamine patch, Ativan, Flexeril Oral Product, Tylenol Suspension; Drug
Lead sponsor: University of California, Davis; Other
Eligibility: 35 Years to 65 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Shoulder Pain, Opioid Use
Interventions: Acetaminophen, Celecoxib 200mg, Celecoxib 400 mg, Ropivacaine, Ketorolac, Acetaminophen Injectable Product, Oxycodone, Tramadol, Morphine Injectable Solution, hydrocodone bitartrate and acetaminophen, Morphine, Oxycodone Hydrochloride, Meloxicam; Drug
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pain, Postoperative, Lung Diseases
Interventions: Intercostal Nerve Cryoablation, Patient-controlled analgesia (PCA); Device · Drug
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years to 85 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Prostatic Neoplasms, Prostate Neoplasms, Prostate Cancer
Interventions: 5-Azacitidine, all trans retinoic acid, Lupron; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older · Male only
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Prostate Cancer
Interventions: Estramustine, Thalidomide, Paclitaxel (Taxol); Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: Male only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2004
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Post-operative Pain
Interventions: Placebo, Pregabalin; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years to 70 Years
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Perforated Appendicitis
Interventions: IV tylenol, No IV tylenol, Ketorolac; Drug
Lead sponsor: Children's Mercy Hospital Kansas City; Other
Eligibility: 2 Years to 17 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Cesarean
Interventions: Not listed
Lead sponsor: Saint Elizabeth Regional Medical Center; Other
Eligibility: 14 Years to 40 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Idiopathic Scoliosis, Post-operative Pain
Interventions: Ketamine, Placebo; Drug · Other
Lead sponsor: Albany Medical College; Other
Eligibility: Not listed
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Albany, New York

Conditions: Post Operative Pain
Interventions: TAP block; Procedure
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Ventral Hernia, Ventral Hernia Repair, Postoperative Pain
Interventions: Bupivicaine, Fentanyl, Thoracic epidural analgesia, Hydromorphone, Acetaminophen, Ketorolac, magnesium sulfate, Tramadol, Gabapentin, Cyclobenzaprine, transversus abdominis plane block; Drug · Device · Procedure
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Prosthetic Joint Infection
Interventions: Oral PCA; Dietary Supplement
Lead sponsor: Dr. Dean Reeves Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Shawnee Mission, Kansas

Conditions: Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis, Pain, Postoperative, Ileus, Ileus Paralytic, Ileus; Mechanical, Constipation Drug Induced, Constipation, Rectum Cancer, Rectum Neoplasm
Interventions: Acetaminophen, Gabapentin, Orphenadrine, Lidocaine, Marcaine, Ketamine, Methadone, Tramadol, Ketorolac, Morphine Sulfate, Fentanyl, Dilaudid, Hydrocodone-Acetaminophen Tab 5-325 MG, HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET; Drug
Lead sponsor: University of Illinois College of Medicine at Peoria; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Peoria, Illinois

Conditions: Pain
Interventions: Gabapentin, Diphenhydramine; Drug
Lead sponsor: Michelle Kinney; Other
Eligibility: 45 Years to 75 Years
Enrollment: 146 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Liver Diseases, Hepatocellular Cancer, Endstage Liver Disease, Liver Cirrhosis
Interventions: Donor pain management; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 21 Years to 60 Years
Enrollment: 177 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2018
U.S. locations: 4
States / cities: Chicago, Illinois • Burlington, Massachusetts • New York, New York + 1 more

Conditions: Spine Surgery
Interventions: Postoperative methadone, Postoperative placebo, Rescue Analgesia; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 70 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Skin Abnormalities
Interventions: Tea, Serum, Moisturizer; Dietary Supplement · Other
Lead sponsor: Integrative Skin Science and Research; Industry
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Multimodal Analgesic Approach
Interventions: Ofirmev, Per Os Acetaminophen; Drug
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 85 Years
Enrollment: 166 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Surgery, Pneumonia, Surgical Site Infection
Interventions: Continuous Sternal Block, Opioid based analgesia; Device · Drug
Lead sponsor: Halyard Health; Industry
Eligibility: 18 Years and older
Enrollment: 647 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 8
States / cities: Birmingham, Alabama • Newark, Delaware • Lexington, Kentucky + 5 more

Conditions: Pain, Postoperative
Interventions: Epidural Analgesia, Parenteral Analgesia (Intravenous); Procedure
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Orange, California

Conditions: Acute Pain, Postoperative
Interventions: IV acetaminophen, Oral acetaminophen, Morphine; Drug
Lead sponsor: Mallinckrodt; Industry
Eligibility: 50 Years to 90 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 2
States / cities: Pensacola, Florida • Columbus, Ohio

Conditions: Pain Management, Analgesia, Anesthetic
Interventions: Opioids delivered through PCA, EXPAREL® infiltration; Drug
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Post-operative Pain
Interventions: Placebo, IV acetaminophen; Drug
Lead sponsor: Aultman Health Foundation; Other
Eligibility: 18 Years to 85 Years · Female only
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Canton, Ohio

Conditions: Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis, Sickle Cell Anemia Crisis, Sickle Cell Anemia in Children, Sickle Cell Anemia (HbSS, or HbSβ-thalassemia0), Sickle Cell Hemoglobin C Disease, Pain Crisis
Interventions: Buprenorphine Buccal Film [Belbuca]; Drug
Lead sponsor: Natasha Archer; Other
Eligibility: 12 Years to 22 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2032
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Multimodal Analgesia Effect on Post Surgical Patient

Multimodal Analgesia in Shoulder Arthroplasty

Efficacy of Intercostal CryoAnalgesia in Robotic Lung Resection

A Pilot Study of 5-AZA and ATRA for Prostate Cancer With PSA-only Recurrence After Local Treatment

Study of Paclitaxel, Estramustine Phosphate and Thalidomide for Patients With Metastatic Androgen-Independent Prostate Carcinoma

Role of Pregabalin in Treatment of Post-Op Pain in Fracture Patients

The Impact of IV Acetaminophen on Pain After Appendectomy for Perforated Appendicitis

Cesarean Postoperative Pain Satisfaction

Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis

Ultrasound-guided Transversus Abdominis Plane Block After Hysterectomy

Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release

PCA Administration in Prosthetic Joint Infection

Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

Preoperative Gabapentin for Acute and Chronic Post-thoracotomy Analgesia

A2ALL-Patients Safety System Improvements in Living Donor Liver Transplantation

Postoperative Oral Methadone After Major Spine Surgery; Safety, Feasibility and Efficacy in Prevention of Progression to Chronic Opioid Usage at 3 Months

Topical and Oral Regimen for Skin Health

IV vs Oral Acetaminophen in Spine Fusion Perioperative Care

Multicenter Infection Surveillance Study Following Open Heart Surgery

Randomized Study Comparing the Use of Epidural Analgesia to Intravenous Narcotics for Laparoscopic Colorectal Resection.

Multicenter Study to Compare Intravenous and Oral Acetaminophen for the Treatment of Acute Moderate to Severe Pain

Post-Operative Pain Management Following Spine Surgery

Efficacy of IV Acetaminophen for Pain Management

Buprenorphine for the Management of Pain in Children With Sickle Cell Disease