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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:55 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 100 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Oral Probiotics Clear all

Conditions: Mania (Neurotic)
Interventions: Probio-Tec BG-VCap-6.5, Placebo; Combination Product · Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Crohn's Disease
Interventions: Growth Hormone, Nutraceutical Combination, Exclusion Diet, Placebo Growth Hormone; Drug · Dietary Supplement · Other
Lead sponsor: Columbia University; Other
Eligibility: 10 Years to 17 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Recurrent Pregnancy Loss, Unexplained Infertility
Interventions: Uterine ERA and microbiome testing, Oral antibiotics and vaginal probiotics; Diagnostic Test · Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Sunnyvale, California

Conditions: Group B Strep Infection
Interventions: Probiotic dietary supplement; Drug
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older · Female only
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Healthy
Interventions: Lactobacillus rhamnosus GG ATCC 53103, Placebo; Biological
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 50 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Children
Interventions: BB-12 supplemented strawberry yogurt, Strawberry flavored yogurt; Drug · Other
Lead sponsor: Georgetown University; Other
Eligibility: 1 Year to 5 Years
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Probiotics
Interventions: SLAB51; Dietary Supplement
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 65 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Bishop, California • La Jolla, California

Conditions: Infant Gut Microbiome
Interventions: B. infantis EVC001, Lacto-N-tetraose (LNT); Other
Lead sponsor: Evolve BioSystems, Inc.; Industry
Eligibility: Up to 60 Days
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Asthma, Obesity, Insulin Resistance
Interventions: Probiotic, Placebo; Dietary Supplement
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 99 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Nephrolithiasis, Hyperoxaluria, Crohn's Disease
Interventions: Oxadrop, Agri-King Synbiotic (AKSB), Placebo; Dietary Supplement · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: HSIL, High Grade Squamous Intraepithelial Lesion, HPV-Related Squamous Cell Carcinoma, Anal HSIL
Interventions: EXE-346 Probiotic, Placebo, Usual Care High Resolution Anoscopy (HRA); Drug · Procedure
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Schizophrenia, Schizoaffective Disorder
Interventions: Synbiotic Supplement, Inert Compound; Biological
Lead sponsor: Sheppard Pratt Health System; Other
Eligibility: 18 Years to 65 Years
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Batlimore, Maryland

Conditions: Mild Gastrointestinal Symptoms in Healthy Adults
Interventions: Bifidobacterium animals subsp. lactis BL04+PreforPro, Bifidobacterium animals subsp. lactis BL04, Placebo; Dietary Supplement · Other
Lead sponsor: Colorado State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 93 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Fort Collins, Colorado

Conditions: Cyanotic Congenital Heart Disease
Interventions: Bifidobacterium infantis, Placebo; Dietary Supplement · Other
Lead sponsor: University of California, Davis; Other
Eligibility: Up to 4 Months
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Oral Cancer
Interventions: ProDentis Lozenge, Placebo Lozenge; Dietary Supplement · Other
Lead sponsor: University of Iowa; Other
Eligibility: 21 Years to 89 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Dysbiosis, Gut -microbiota, Microbiome Analysis, Probiotic, Antibiotic Prophylaxis
Interventions: Placebo Capsule, Probiotic with Human Milk Oligosaccharides (HMO); Drug · Dietary Supplement
Lead sponsor: Acibadem Maslak Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Anxiety Disorders and Symptoms, Fibromyalgia, Arthritis, Chronic Pain, Hypertension,Essential
Interventions: IV Vitamin Infused Therapy Treatment, Herbal medicine; Dietary Supplement · Drug
Lead sponsor: Faith A. Richardson; Other
Eligibility: 21 Years to 80 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Dover, Delaware

Conditions: Post Traumatic Stress Disorder, Inflammation
Interventions: Lactobacillus rhamnosus GG (LGG; ATCC strain 53103; CRMTS #11272; PTS #3766), Placebo; Biological · Other
Lead sponsor: VA Eastern Colorado Health Care System; Federal
Eligibility: 18 Years to 60 Years
Enrollment: 383 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Oral Health
Interventions: ProBiora3 mints, Placebo tablet; Other
Lead sponsor: Oragenics, Inc.; Industry
Eligibility: 18 Years to 35 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2012
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Infant Development, Gut Microbiome, Food Protein Induced Allergic Proctocolitis
Interventions: INF108F probiotic, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 1 Day to 90 Days
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Newton, Massachusetts

Conditions: COPD, Obstructive Lung Disease
Interventions: Lactobacillus GG, Sugar pill; Dietary Supplement · Other
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years to 99 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Rheumatoid Arthritis (RA)
Interventions: Align Extra Strength Probiotic Supplement; Dietary Supplement
Lead sponsor: Ancilia Biosciences; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Overactive Bladder
Interventions: Lactobacillus Probiotic Capsule, Matching Lactobacillus Probiotic Placebo Capsule; Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older · Female only
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Hillsborough, North Carolina • Raleigh, North Carolina

Conditions: Autism Spectrum Disorder
Interventions: intranasal oxytocin, oral probiotics, oral placebo; Drug · Dietary Supplement
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 3 Years to 25 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Search by objective public record fields.

A Probiotic Intervention to Prevent Relapse Following Hospitalization for Mania

Growth Hormone and Exclusion Diet Therapy in Juvenile Crohn's Disease

Assessing the Endometrial Environment in Recurrent Pregnancy Loss and Unexplained Infertility

Group B Streptococcus Response After Probiotic Exposure

Safety of Lactobacillus Rhamnosus GG ATCC 53103 (LGG) in Healthy Volunteers

Safety of BB-12 Supplemented Strawberry Yogurt For Healthy Children

The Effect of a Multi-strain Probiotic on Acclimatization to High Altitude

The EFFECT Study: Probiotic and HMO Supplementation in Infants

Probiotics and Insulin Resistance in Obese Asthmatics

Use of Oral Probiotics to Reduce Urinary Oxalate Excretion

CASCADE 2002: PROTECT Study, "PRObiotics to TrEat Anal preCancer Trial

Synbiotic Compound to Reduce Symptoms of Schizophrenia

BacterioPHAGE for Gastrointestinal Health 2 Study

Probiotics in Infants With Cyanotic Congenital Heart Disease

The Oral Microbiome in OSCC

Impact of Probiotics on Gut Microbiome During Antibiotic Prophylaxis in Elective Orthopedic Surgery

The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature

Probiotic (LGG) for Veterans With PTSD

Effect of an Oral Probiotic Tablet on Oral Bacteria and Clinical Measurements (ProBiora3)

INF108F in Infants With Food Protein Induced Proctocolitis

Probiotic Use in Patients With Prior COPD Exacerbation

Probiotics in Adults With Rheumatoid Arthritis

Optimizing Overactive Bladder Treatment

Probiotics and Oxytocin Nasal Spray on Social Behaviors of Autism Spectrum Disorder (ASD) Children