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Showing 1–24 of 56 matching trials from the live ClinicalTrials.gov search.
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Terminated Not applicable Interventional Accepts healthy volunteers

The Effect of the DryMouth Shield on Snoring

NCT03701165
Conditions
Snoring
Interventions
DryMouth Shield
Device
Lead sponsor
VMS Medical Products, Inc
Industry
Eligibility
18 Years to 99 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Huntersville, North Carolina
Not listed Not applicable Interventional Accepts healthy volunteers

Pilot Study for Feasibility of Using an Oral Appliance for Decreasing Snoring

NCT04900285
Conditions
Snoring
Interventions
Delta Dental Oral Device
Device
Lead sponsor
Norton Healthcare
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Louisville, Kentucky
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Sleep Quality During Pregnancy Using an Oral Appliance

NCT03646214
Conditions
Snoring, Sleep Fragmentation
Interventions
Midline traction oral appliance
Device
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Remineralization of Molar Incisor Hypomineralization (MIH) With a Hydroxyapatite Toothpaste

NCT05485662
Conditions
Molar Incisor Hypomineralization
Interventions
Hydroxyapatite toothpaste, Sodium Fluoride Toothpaste
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Dental Caries
Interventions
Negative Control Toothpaste, Active Comparator, Test toothpaste
Drug
Lead sponsor
Church & Dwight Company, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Noblesville, Indiana
Terminated Not applicable Interventional

Severe OSA Study (SOS)

NCT05445869
Conditions
Obstructive Sleep Apnea, Sleep Apnea
Interventions
ProSomnus® EVO Sleep and Snore Device
Device
Lead sponsor
ProSomnus Sleep Technologies
Industry
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
5
States / cities
Redwood City, California • Boston, Massachusetts • Minneapolis, Minnesota + 2 more
Active, not recruiting No phase listed Observational

RPMO2 Oximeter Accuracy During Sleep 1 Trial

NCT07397780
Conditions
Obstructive Sleep Apnea
Interventions
RPMO2 OSA Device
Device
Lead sponsor
ProSomnus Sleep Technologies
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Malocclusion
Interventions
Extraoral OrthoPulse® PBM, Fixed Orthodontic Appliance Treatment
Device · Other
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
11 Years to 40 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Birmingham, Alabama • Suwanee, Georgia
Conditions
Dental Plaque Accumulation
Interventions
Standard Toothbrush, Ortho-Buddy
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
11 Years to 18 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Newark, New Jersey
Conditions
Sleep Apnea, Obstructive
Interventions
Positive Airway Pressure (PAP), Oral Appliance (OA)
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
4
States / cities
Redwood City, California • Boston, Massachusetts • Philadelphia, Pennsylvania + 1 more
Conditions
Obstructive Sleep Apnea
Interventions
Oral appliance, Oxygen, Oral appliance plus oxygen, No treatment
Device · Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 79 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Obstructive Sleep Apnea
Interventions
MATRx plus test
Device
Lead sponsor
Zephyr Sleep Technologies
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Timeline
2018 – 2019
U.S. locations
1
States / cities
Raleigh, North Carolina
Conditions
Obstructive Sleep Apnea
Interventions
A novel monitoring suite of sensors will be inserted into the standard oral device.
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Lebanon, New Hampshire
Conditions
Obstructive Sleep Apnea of Adult, Pregnancy Related
Interventions
Mandibular advancement Device
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 40 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Detroit, Michigan
Recruiting Not applicable Interventional Accepts healthy volunteers

Study of the Use of Orthopulse Photobiomodulation

NCT05650359
Conditions
Orthodontics
Interventions
OrthoPulse, No intervention
Device · Other
Lead sponsor
Biolux Technology GmbH
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Chandler, Arizona
Conditions
Cleft Lip, Cleft Palate, Cleft Lip and Palate
Interventions
cleft lip repair, cleft palate repair, oronasal fistula repair, pharyngoplasty, gingivoperiosteoplasty, LeFort-1 maxillary repositioning, rhinoplasty, myringotomy and tympanostomy tube placement, speech therapy, orthodontia, presurgical orthopedics, sound amplification for hearing
Procedure · Other · Device
Lead sponsor
Duke University
Other
Eligibility
1 Day to 22 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2031
U.S. locations
10
States / cities
Gainesville, Florida • Hollywood, Florida • Orlando, Florida + 7 more
Conditions
Obstructive Sleep Apnea
Interventions
CPAP, MAD
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Sleep Apnea, Obstructive
Interventions
Oral appliance, BluePro oral appliance
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Safety Monitoring for a Novel 3D Printed Mandibular Advancement Device

NCT05018234
Conditions
Obstructive Sleep Apnea
Interventions
Noval Oral Appliance
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Conditions
Obstructive Sleep Apnea (OSAS), Obstructive Sleep Apnea (SAOS)
Interventions
Under-mattress monitor, level 3 Home Sleep Apnea Test, Mandibular Advancement Device (MAD)
Device
Lead sponsor
Isabel Moreno Hay
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Obstructive Sleep Apnea, Cognitive Decline
Interventions
Positive airway pressure, Oral appliance therapy, Positional therapy
Device
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
55 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Tucson, Arizona • New York, New York • Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Intra Oral Application (IOA) Testing Study of a Stannous Toothpaste

NCT07419672
Conditions
Dental Caries
Interventions
Negative Control Treatment Slurry (Fluoride-Free), Active Comparator Fluoride Treatment (0.454% SnF), Test Fluoride Treatment (0.454% SnF) (Investigational Toothpaste)
Drug
Lead sponsor
Church & Dwight Company, Inc.
Industry
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Noblesville, Indiana
Conditions
Malocclusion
Interventions
OrthoPulse™
Device
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
11 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Suwanee, Georgia
Not listed No phase listed Observational Accepts healthy volunteers

Early Caries Lesion Management Observational Study

NCT04933331
Conditions
Initial Caries, Arrested Dental Caries, Cavitated Caries, Dental Caries, Dental Caries in Children
Interventions
Curodont Repair Fluoride Plus, Silver Diamine Fluoride, Glass Ionomer Sealant, Fluoride varnish, Fluoride toothpaste
Drug · Device
Lead sponsor
CareQuest Institute for Oral Health
Other
Eligibility
4 Years and older
Enrollment
744 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
4
States / cities
Dothan, Alabama • Westborough, Massachusetts • Bend, Oregon + 1 more