- Conditions
- Congestive Heart Failure, Renal Insufficiency
- Interventions
- Hypertonic saline, then oral sodium chloride, Normal saline, then oral placebo capsule
- Drug
- Lead sponsor
- Barnes-Jewish Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
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Showing 1–6
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- Conditions
- Exercise-associated Hyponatremia
- Interventions
- Intravenous hypertonic Saline, Oral hypertonic saline
- Other
- Lead sponsor
- Western States Endurance Run Research Foundation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Healthy
- Interventions
- Tolvaptan, Hypertonic saline infusion
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 21 Years to 55 Years · Male only
- Enrollment
- 17 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Rhinovirus
- Interventions
- Nasal Swab Healthy Surveillance, Nasal Swab Sick Samples, Nasal Swab Hospitalized Cohort, Sick Follow-up Survey, Older Cohort Control Group, Procedural Comfort or Care
- Diagnostic Test · Other
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- Up to 17 Years
- Enrollment
- 670 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Primary Ciliary Dyskinesia
- Interventions
- VX-371, Hypertonic Saline, Placebo (0.17% saline), VX-371 + HS, Ivacaftor
- Drug
- Lead sponsor
- Parion Sciences
- Industry
- Eligibility
- 12 Years and older
- Enrollment
- 123 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 21
- States / cities
- Birmingham, Alabama • Palo Alto, California • Aurora, Colorado + 18 more
- Conditions
- Cystic Fibrosis
- Interventions
- VX-371 + HS, Hypertonic saline, Placebo, Orkambi, VX-371
- Drug
- Lead sponsor
- Parion Sciences
- Industry
- Eligibility
- 12 Years and older
- Enrollment
- 147 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 30
- States / cities
- Little Rock, Arkansas • Oakland, California • Gainesville, Florida + 27 more