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ClinicalTrials.gov public records Last synced Nov 11, 2026, 8:14 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Orally-administered probiotic Clear all

Conditions: Vaginal Odor
Interventions: Orally-administered probiotic, Placebo; Dietary Supplement
Lead sponsor: Bonafide Health; Industry
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Harrison, New York

Conditions: Microbial Composition, Immune Function
Interventions: Probiotic Capsule, Placebo; Drug
Lead sponsor: Sheffield Hallam University; Other
Eligibility: 18 Years to 40 Years · Male only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Urinary Tract Infections
Interventions: E. coli Nissle 1917; Drug
Lead sponsor: Elizabeth Lucas; Other
Eligibility: 21 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Vancomycin Resistant Enterococcal Colonization
Interventions: Lactobacillus GG or Culturelle; Biological
Lead sponsor: Tufts Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Bacteriuria
Interventions: Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1; Dietary Supplement
Lead sponsor: Baylor College of Medicine; Other
Eligibility: Up to 18 Years · Female only
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Enteric Hyperoxaluria
Interventions: SYNB8802v1, Placebo; Drug · Other
Lead sponsor: Synlogic; Industry
Eligibility: 18 Years to 74 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Pregnancy
Interventions: Probiotic dietary supplement; Dietary Supplement
Lead sponsor: Marquette University; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Obesity
Interventions: Lactobacillus Rhamnosus GG, Placebo; Dietary Supplement
Lead sponsor: Tufts Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Alzheimer Disease
Interventions: Probiotic, Placebo; Drug · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 60 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Clostridium Difficile Infection
Interventions: FZ002, Placebo for FZ002; Biological · Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 75 Years
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Mania (Neurotic)
Interventions: Probio-Tec BG-VCap-6.5, Placebo; Combination Product · Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Dysbiosis, Gut -microbiota, Microbiome Analysis, Probiotic, Antibiotic Prophylaxis
Interventions: Placebo Capsule, Probiotic with Human Milk Oligosaccharides (HMO); Drug · Dietary Supplement
Lead sponsor: Acibadem Maslak Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Crohn's Disease
Interventions: Growth Hormone, Nutraceutical Combination, Exclusion Diet, Placebo Growth Hormone; Drug · Dietary Supplement · Other
Lead sponsor: Columbia University; Other
Eligibility: 10 Years to 17 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Hirschsprung Disease
Interventions: VSL#3, Placebo; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 1 Month to 12 Months
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 2
States / cities: Ann Arbor, Michigan • Buffalo, New York

Conditions: Coronary Artery Disease
Interventions: GoodBelly Probiotic, Vancomycin; Dietary Supplement · Drug
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 40 Years to 75 Years · Male only
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Milwauke, Wisconsin

Conditions: Healthy
Interventions: Bifidobacterium lactis (BB-12), Placebo; Drug
Lead sponsor: Georgetown University; Other
Eligibility: 1 Year to 3 Years
Enrollment: 182 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Autism
Interventions: Synbiotic, Prebiotic; Dietary Supplement
Lead sponsor: University of California, Davis; Other
Eligibility: 2 Years to 11 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Ventilator Associated Pneumonia, Infections, C-Difficile, Antibiotic-associated Diarrhea, Diarrhea
Interventions: L. rhamnosus GG - Probiotic, Placebo - Microcrystalline Cellulose; Drug
Lead sponsor: McMaster University; Other
Eligibility: 18 Years and older
Enrollment: 2,650 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 2
States / cities: Rochester, Minnesota • St Louis, Missouri

Conditions: Probiotics
Interventions: SLAB51; Dietary Supplement
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 65 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 2
States / cities: Bishop, California • La Jolla, California

Conditions: Metabolism
Interventions: Visbiome; Dietary Supplement
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 40 Years · Male only
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Seattle, Washington

Search by objective public record fields.

The Effects of an Orally-Administered Probiotic on Vaginal Symptoms

Gut Microbiome Response to Long-Haul Travel in Elite Football Players

Open Label Trial of Nissle 1917

Probiotic Lactobacillus GG to Eliminate VRE Colonization

Bacteriuria Eradication Through Probiotics

Safety, Tolerability, and Pharmacodynamics of SYNB8802v1 in Subjects With History of Gastric Bypass Surgery or Short-bowel Syndrome

Quasi Experiment of Prenatal Probiotics Against Group B Streptococcus Colonization

Does Weight Loss Surgery and Probiotic Supplementation Lead to a "Lean" Gut Microbiota?

The Gut - PRO Study

A Safety Trial to Evaluate an Orally Ingested Yeast Modified to Express a Tetra-specific Anti-toxin for Clostridioides Difficile

A Probiotic Intervention to Prevent Relapse Following Hospitalization for Mania

Impact of Probiotics on Gut Microbiome During Antibiotic Prophylaxis in Elective Orthopedic Surgery

Growth Hormone and Exclusion Diet Therapy in Juvenile Crohn's Disease

Probiotic Prophylaxis of Hirschprung's Disease Associated Enterocolitis (HAEC)

Effect of Probiotic Supplementation on Endothelial Function

Study to Investigate the Potential of Probiotics in Yogurt

Effect of Milk Oligosaccharides and Bifidobacteria on the Intestinal Microflora of Children With Autism

Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial

The Effect of a Multi-strain Probiotic on Acclimatization to High Altitude

Impact of Probiotics on Drug, Vitamin, and Hormone Metabolism