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ClinicalTrials.gov public records Last synced Oct 4, 2026, 3:38 PM EDT

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Showing 25–48 of 303 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Osteoarthritis Intervention Clear all
Completed Not applicable Interventional Results available

STepped Exercise Program for Knee OsteoArthritis

NCT02653768
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Stepped Exercise Program, Arthritis Education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
345 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Oct 4, 2026, 3:38 PM EDT
Not listed Not applicable Interventional

Impact of Sensor Technology in Knee OA

NCT05222503
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Knee Brace + OPUM Digital Knee, Knee Brace
Device
Lead sponsor
OPUM Technologies US LTD
Other
Eligibility
40 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Oct 4, 2026, 3:38 PM EDT
Completed No phase listed Observational

Clinical and Economic Comparison of Robot Assisted Versus Manual Knee Replacement

NCT01705886
View directory record Official record
Conditions
Knee Arthroplasty
Interventions
Total Knee Arthroplasty, MAKO® Robot Assisted Medial Knee Arthroplasty, RESTORIS Multicompartmental Knee System, Depuy Knee Replacement System, Stryker® Knee Replacement System
Procedure · Device
Lead sponsor
Northwest Surgical Specialists, Vancouver
Other
Eligibility
21 Years to 80 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Vancouver, Washington
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 4, 2026, 3:38 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Upper and Lower Extremity Exercise and Exercise-Induced Hypoalgesia in Knee Osteoarthritis

NCT06105788
View directory record Official record
Conditions
Knee Osteoarthritis, Knee Pain Chronic, Central Pain Syndrome
Interventions
Exercise
Other
Lead sponsor
University of Texas, El Paso
Other
Eligibility
45 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Dec 16, 2024 · Synced Oct 4, 2026, 3:38 PM EDT
Terminated No phase listed Observational

Clinical Outcomes of Knee Replacement

NCT01705366
View directory record Official record
Conditions
Knee Arthroplasty
Interventions
Non-MAKO® Robot Assisted Total Knee Arthroplasty, MAKO® Robot Assisted Medial Knee Arthroplasty, MAKO® Robot Assisted Medial and PF Knee Arthroplasty, RESTORIS Multicompartmental Knee System, Depuy Knee Replacement System, Stryker® Knee Replacement System
Procedure · Device
Lead sponsor
Northwest Surgical Specialists, Vancouver
Other
Eligibility
21 Years and older
Enrollment
316 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Vancouver, Washington
Source: ClinicalTrials.gov public record
Updated Sep 26, 2018 · Synced Oct 4, 2026, 3:38 PM EDT
Completed Phase 4 Interventional Results available

Bone Marrow Aspirate Compared to Platelet Rich Plasma for Treating Knee Osteoarthritis

NCT03289416
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Pure PRP II, PureBMC
Combination Product
Lead sponsor
Andrews Research & Education Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Gulf Breeze, Florida
Source: ClinicalTrials.gov public record
Updated Apr 20, 2025 · Synced Oct 4, 2026, 3:38 PM EDT
Completed Not applicable Interventional

A Pilot Observational Clinical Survey: Impacts of Tahitian Noni Juice on the Quality of Life of Patients With Osteoarthritis

NCT01070264
View directory record Official record
Conditions
Osteoarthritis
Interventions
Noni Juice
Dietary Supplement
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
40 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Rockford, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 17, 2010 · Synced Oct 4, 2026, 3:38 PM EDT
Completed No phase listed Observational

Evaluation of Bone Mineral Density Changes After Total Hip Replacement: A Two-Year Clinical and DXA Analysis

NCT02865447
View directory record Official record
Conditions
Joint Disease
Interventions
total hip arthroplasty implant
Device
Lead sponsor
MicroPort Orthopedics Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced Oct 4, 2026, 3:38 PM EDT
Terminated Not applicable Interventional

Comparison of Training Load With/Out Blood Flow Restriction Training in Rheumatoid Populations

NCT04309227
View directory record Official record
Conditions
Rheumatoid Arthritis, Myositis, Osteoarthritis, Weakness, Muscle
Interventions
Strength Training
Other
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 85 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 22, 2024 · Synced Oct 4, 2026, 3:38 PM EDT
Recruiting Not applicable Interventional

Healthier: Health Coaching for People With Rheumatoid Arthritis to Improve Mental Well-Being

NCT07222696
View directory record Official record
Conditions
Rheumatoid Arthritis (RA
Interventions
Peer Coach, Healthy Horizons
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 4, 2026, 3:38 PM EDT
Completed Not applicable Interventional

Patient and Provider Interventions for Managing Osteoarthritis in Primary Care

NCT01435109
View directory record Official record
Conditions
Osteoarthritis
Interventions
Patient Behavioral Intervention for OA, Provider Intervention for OA, Combined Patient and Provider Interventions for OA
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
537 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 8, 2016 · Synced Oct 4, 2026, 3:38 PM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time

NCT01240863
View directory record Official record
Conditions
Chronic Pain
Interventions
Hydrocodone ER, Placebo
Drug
Lead sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
391 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
73
States / cities
Mobile, Alabama • Chandler, Arizona • Scottsdale, Arizona + 63 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2017 · Synced Oct 4, 2026, 3:38 PM EDT
Terminated Phase 2 Interventional

A Study to Evaluate an Intra-Articular Injection of ZILRETTA Versus Triamcinolone Acetonide, Immediate Release in Subjects With Osteoarthritis of the Hip

NCT06977568
View directory record Official record
Conditions
Osteoarthritis of Hip
Interventions
Zilretta, Triamcinolone Acetonide
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
50 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 4, 2026, 3:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Core Activation and Stabilization for Knee OA

NCT03776981
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Core Activation, Core Stabilization
Other
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
40 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 25, 2020 · Synced Oct 4, 2026, 3:38 PM EDT
Completed Not applicable Interventional Results available

Improving Function After Knee Arthroplasty With Weight-Bearing Biofeedback

NCT01333189
View directory record Official record
Conditions
Arthropathy of Knee Joint
Interventions
Weight-bearing biofeedback exercise, Standard of care exercise
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years to 85 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 23, 2019 · Synced Oct 4, 2026, 3:38 PM EDT
Recruiting Not applicable Interventional

Activating SilverSneakers Benefits for Seniors With Osteoarthritis

NCT06782347
View directory record Official record
Conditions
Osteoarthritis, Physical Inactivity
Interventions
Proactive Care
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
65 Years and older
Enrollment
1,454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 4, 2026, 3:38 PM EDT
Not listed Phase 2 Interventional

Safety & Efficacy FloGraft (Micronized Human Amnion Chorion Membrane)® in Adults With Pain Due to OA of the Knee

NCT03441607
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
mHACMb, placebo
Drug · Other
Lead sponsor
Applied Biologics, LLC
Industry
Eligibility
30 Years and older
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 28, 2018 · Synced Oct 4, 2026, 3:38 PM EDT
Completed Not applicable Interventional

Bariatric Lap Band Surgery as a Treatment for Knee Osteoarthritis

NCT02272218
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
bariatric lap band surgery
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
25 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Oct 4, 2026, 3:38 PM EDT
Completed Not applicable Interventional Results available

Efficacy Study of an Unloading Brace for Knee Osteoarthritis

NCT02150057
View directory record Official record
Conditions
Osteoarthritis of the Knee
Interventions
Breg Fusion Unloading Brace
Device
Lead sponsor
Andrews Research & Education Foundation
Other
Eligibility
30 Years to 80 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Gulf Breeze, Florida
Source: ClinicalTrials.gov public record
Updated Oct 22, 2019 · Synced Oct 4, 2026, 3:38 PM EDT
Completed Not applicable Interventional Results available

Geniculate Artery Embolization for Knee Pain Secondary to Osteoarthritis (OA)

NCT03362957
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Geniculate Artery Embolization, Sham Procedure
Device · Diagnostic Test
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
40 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Woodbridge, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Oct 4, 2026, 3:38 PM EDT
Completed Not applicable Interventional

Closed Suction Drainage in Shoulder Arthroplasty

NCT02767453
View directory record Official record
Conditions
Osteoarthritis
Interventions
Wound drainage, Total Shoulder Arthroplasty
Procedure
Lead sponsor
Columbia University
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 27, 2019 · Synced Oct 4, 2026, 3:38 PM EDT
Not listed Not applicable Interventional

Wearable Sensor-based Balance Training for Patients With Knee Osteoarthritis

NCT02620462
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Wearable sensor-based exercise training
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 90 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 17, 2016 · Synced Oct 4, 2026, 3:38 PM EDT
Completed Not applicable Interventional Results available

Cryoneurolysis for Improvements in Pain, ADL and QOL in Patients With Ankle Osteoarthritis

NCT03567187
View directory record Official record
Conditions
Ankle Osteoarthritis
Interventions
iovera
Device
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 4, 2026, 3:38 PM EDT
Completed Not applicable Interventional Results available

Exercise Intervention to Reduce Postural Instability in Osteoarthritis

NCT00708734
View directory record Official record
Conditions
Osteoarthritis
Interventions
functional exercise training
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
50 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 23, 2014 · Synced Oct 4, 2026, 3:38 PM EDT