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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Osteoarthritis Self-Management Clear all
Completed Not applicable Interventional

The Kaia Hip and Knee Pain Intervention for Self-management of the Pain in Patients With Osteoarthritis.

NCT04615377
View directory record Official record
Conditions
Knee Osteoarthritis, Hip Osteoarthritis
Interventions
Kaia hip and knee pain application, Treatment as usual
Behavioral · Other
Lead sponsor
Kaia Health Software
Industry
Eligibility
22 Years to 75 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 15, 2022 · Synced Sep 23, 2026, 2:54 AM EDT
Terminated Not applicable Interventional

Improving Walking Quality and Quantity in Osteoarthritis (IWALQQ-OA)

NCT03064139
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
MCG, SCG
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
50 Years to 80 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional

Exercise Plus Activity Strategy Training for Osteoarthritis

NCT00613678
View directory record Official record
Conditions
Osteoarthritis
Interventions
Activity Strategy Training, Education
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
62 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Sep 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional

Patient Education in Rheumatoid Arthritis and Osteoarthritis

NCT00000414
View directory record Official record
Conditions
Rheumatoid Arthritis, Osteoarthritis
Interventions
Arthritis Self-Management Program, SMART Program
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2001
U.S. locations
4
States / cities
Palo Alto, California • Wichita, Kansas • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 20, 2013 · Synced Sep 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Self-Management of Osteoarthritis

NCT00288912
View directory record Official record
Conditions
Osteoarthritis
Interventions
Health Education, Osteoarthritis Self-Management
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
523 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 23, 2015 · Synced Sep 23, 2026, 2:54 AM EDT
Completed Phase 4 Interventional Results available

Evaluation of Methods of Teaching Self-management Strategies to Patients With Symptomatic Knee Osteoarthritis

NCT03245463
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Educational handout, Verbal script, Hyaluronic Acid
Other · Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Sep 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional

Use of a Self-Guided Mindfulness Mobile Application to Improve Pain Outcomes in Individuals With Knee Osteoarthritis

NCT03936088
View directory record Official record
Conditions
Osteo Arthritis Knee, Pain
Interventions
Intervention -- "Headspace" mindfulness application, Control -- "My Water Balance" application
Device
Lead sponsor
jilliansylvester
Federal
Eligibility
18 Years to 74 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Scott Air Force Base, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 12, 2022 · Synced Sep 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Results available

Mobile Motivational Physical Activity Targeted Intervention

NCT03160287
View directory record Official record
Conditions
Osteoarthritis
Interventions
Motivaltional interviews and infrequent motivational text messages
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
65 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Sep 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Collaborative Lifestyle Intervention Program in Knee Osteoarthritis Patients

NCT02835326
View directory record Official record
Conditions
Osteoarthritis
Interventions
Exercise and Dietary Weight Loss, Walk with Ease
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
50 Years and older
Enrollment
227 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 11, 2022 · Synced Sep 23, 2026, 2:54 AM EDT
Not yet recruiting Not applicable Interventional

taVNS in Veterans With Knee OA (AVAHCS)

NCT07804199
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Methylprednisolone acetate, taVNS
Drug · Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Results available

Home-based tDCS and Mindfulness-based Meditation for Self-management of Clinical Pain and Symptoms

NCT04375072
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
active tDCS paired with active MBM, sham tDCS paired with active MBM, active tDCS paired with sham MBM, sham tDCS paired with sham MBM
Device
Lead sponsor
University of Arizona
Other
Eligibility
50 Years to 85 Years
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 23, 2026, 2:54 AM EDT
Active, not recruiting Not applicable Interventional

Non-Surgical Management of Knee Osteoarthritis in the Military Health System (MHS)

NCT03747393
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
DoD/VA CPG Core Set + PT, DoD/VA CPG Core Set
Behavioral
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 60 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
3
States / cities
San Antonio, Texas • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional

Effect of Implanting Allogenic Cytokines Derived From Human Amniotic Membrane (HAM) and Mesenchymal Stem Cells Derived From Human Umbilical Cord Wharton's Jelly (HUMCWJ) on Pain and Functioning of Knee Osteoarthritis

NCT03337243
View directory record Official record
Conditions
Knee Osteoarthritis, Knee Pain Chronic, Joint Disease, Arthritis, Osteo Arthritis Knee, Musculoskeletal Disease
Interventions
HAM and HUMCWJ Injections
Procedure
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
50 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2020 · Synced Sep 23, 2026, 2:54 AM EDT
Recruiting Phase 3 Interventional

The Beat Pain Better Trial

NCT06932887
View directory record Official record
Conditions
Osteoarthritis, Chronic Pain Management
Interventions
Text Messaging, Motivational Messaging, Physical Activity Counseling and Self-Directed Walk with Ease, Enhanced Walk with Ease
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
45 Years and older
Enrollment
346 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
Salt Lake City, Utah • West Valley City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 23, 2026, 2:54 AM EDT
Recruiting Not applicable Interventional

Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)

NCT05792189
View directory record Official record
Conditions
Distal Femur Fracture
Interventions
Timed Up and Go Test on subjects with ORIF of distal femur fractures, Koos Jr assesment on subjects with ORIF of distal femur fractures, Timed Up and Go Test on subjects with DFR of distal femur fracture, Koos Jr assesment on subjects with DFR of distal femur fracture
Other
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional

Community-Based Programs for Improving Physical Function in People With Early Knee Osteoarthritis

NCT00586300
View directory record Official record
Conditions
Osteoarthritis
Interventions
Physical training program, Self-management training program, Physical training and self-management training programs
Other · Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
35 Years to 64 Years
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 20, 2012 · Synced Sep 23, 2026, 2:54 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Empowered Relief Study

NCT07562750
View directory record Official record
Conditions
Osteoarthritis (OA)
Interventions
Empowered Relief, "Self Management Strategies" handout
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 23, 2026, 2:54 AM EDT
Completed No phase listed Observational

Conjoint Analysis of Treatment Preferences for Osteoarthritis

NCT01003925
View directory record Official record
Conditions
Osteoarthritis
Interventions
Standard of care for osteoarthritis treatment, Conjoint Analysis for Osteoarthritis
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
65 Years to 95 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 23, 2015 · Synced Sep 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional

Couples-Oriented Psychosocial Intervention for Osteoarthritis

NCT00230945
View directory record Official record
Conditions
Osteoarthritis
Interventions
education and support intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years and older
Enrollment
543 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 27, 2008 · Synced Sep 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fit and Strong! Plus Comparative Effectiveness Trial

NCT03180008
View directory record Official record
Conditions
Osteoarthritis, Overweight and Obesity
Interventions
Fit and Strong!, Fit and Strong! Plus
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
60 Years and older
Enrollment
413 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Sep 23, 2026, 2:54 AM EDT
Active, not recruiting Not applicable Interventional

Efficacy of an Evidence-based Telehealth Intervention in Modifying Health Behavior

NCT07187024
View directory record Official record
Conditions
Post-traumatic Osteoarthritis, Knee Sprain, Knee Injuries
Interventions
mCare PTOA Intervention
Behavioral
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 54 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 23, 2026, 2:54 AM EDT
Completed Not applicable Interventional Results available

Self Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis

NCT03425019
View directory record Official record
Conditions
Knee Osteoarthritis, Chronic Pain
Interventions
Soterix 1x1 tDCS mini-CT Stimulator device
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
50 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2021 · Synced Sep 23, 2026, 2:54 AM EDT