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Showing 1–24 of 143 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Osteopathic Manipulative Treatments Clear all
Completed Early Phase 1 Interventional

Hyperbaric Oxygen and Manipulative Therapies to Regain Function Post Stroke

NCT03352232
View directory record Official record
Conditions
Stroke, Motor Dysfunction, Chronic Stroke, Ischemic Stroke
Interventions
HBOT and OMT
Combination Product
Lead sponsor
Abington Memorial Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Abington, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 20, 2021 · Synced Sep 23, 2026, 3:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inflammatory Response to OMT

NCT06820684
View directory record Official record
Conditions
Inflammation, Inflammatory Response
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Pacific Northwest University of Health Sciences
Other
Eligibility
18 Years to 59 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Yakima, Washington
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Sep 23, 2026, 3:06 PM EDT
Recruiting Not applicable Interventional

Chronic Low Back Pain and Osteopathic Manipulation Treatment

NCT07161661
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP), Low Back Pain
Interventions
Usual VA Care, Osteopathic manipulative treatment
Procedure
Lead sponsor
Edward Hines Jr. VA Hospital
Federal
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 23, 2026, 3:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

OMT to Improve Feeding After Hypothermia

NCT03380013
View directory record Official record
Conditions
Neonatal Encephalopathy, Feeding; Difficult, Newborn
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
MaineHealth
Other
Eligibility
37 Weeks and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated May 30, 2019 · Synced Sep 23, 2026, 3:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Osteopathic Manipulative Treatment on Neuromuscular Control of the Head-neck System

NCT02261259
View directory record Official record
Conditions
Neck Pain
Interventions
Osteopathic manipulative treatment
Procedure
Lead sponsor
Michigan State University
Other
Eligibility
21 Years to 65 Years
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
3
States / cities
East Lansing, Michigan • Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 3, 2019 · Synced Sep 23, 2026, 3:06 PM EDT
Not listed Not applicable Interventional

Diabetes and Osteopathic Manipulative Medicine (OMM)

NCT03663322
View directory record Official record
Conditions
Type2 Diabetes Mellitus, Osteopathy in Diseases Classified Elsewhere
Interventions
OMT Protocol, OMT-Sham Protocol
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
30 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Central Islip, New York • Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated May 1, 2022 · Synced Sep 23, 2026, 3:06 PM EDT
Recruiting Not applicable Interventional

Effects of Osteopathic Manipulative Treatment Protocol on Sleep Quality in Parkinson's Disease Subjects

NCT06671600
View directory record Official record
Conditions
Parkinsons Disease, Sleep
Interventions
Osteopathic Manipulative Treatment, Sham (No Treatment)
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 23, 2026, 3:06 PM EDT
Not yet recruiting Not applicable Interventional

Osteopathic Manipulative Treatment for Children With Chronic or Recurrent Otitis Media

NCT07639775
View directory record Official record
Conditions
Otitis Media, Otitis Media Effusion, Otitis Media Recurrent, Otitis Media With Effusion in Children, Otitis Media Chronic, Otitis Media in Children, Tympanostomy Tube Insertion, Osteopathic Manipulative Treatment (OMT)
Interventions
Experimental Osteopathic Manipulative Treatment (OMT) Protocol, Control Osteopathic Manipulative Treatment (OMT) Protocol
Other
Lead sponsor
Sarah Vidal
Other
Eligibility
6 Months to 6 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Lynchburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 23, 2026, 3:06 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Techniques for the Treatment of Chronic Migraine Headaches

NCT04520425
View directory record Official record
Conditions
Chronic Migraine, Headache
Interventions
Osteopathic manipulative therapy
Procedure
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 23, 2026, 3:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Osteopathic Cranial Manipulative Medicine on Visual Function

NCT02728713
View directory record Official record
Conditions
Visual Function
Interventions
Cranial Manipulation, Sham/Placebo
Procedure
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 35 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Apr 4, 2016 · Synced Sep 23, 2026, 3:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of Osteopathic Manipulative Treatment (OMT) and Vestibular Rehabilitation Therapy (VRT) in Individuals With Vertigo

NCT01529151
View directory record Official record
Conditions
Vertigo, Dizziness, Benign Paroxysmal Positional Vertigo, Labyrinthitis
Interventions
Osteopathic Manipulative Treatment (OMT), Vestibular Rehabilitation Therapy (VRT)
Other
Lead sponsor
Western University of Health Sciences
Other
Eligibility
18 Years to 79 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Jun 9, 2015 · Synced Sep 23, 2026, 3:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Facial Effleurage on Acute Rhinosinusitis

NCT04642989
View directory record Official record
Conditions
Rhinosinusitis Acute
Interventions
Sham Treatment, Facial Effleurage, Antibiotics
Other · Drug
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 69 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Spartanburg, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Sep 23, 2026, 3:06 PM EDT
Completed Phase 2 Interventional

Nervous System Manipulation and Botanicals for the Treatment of Recurrent Ear Infections in Children

NCT00010465
View directory record Official record
Conditions
Otitis Media
Interventions
Craniosacral Osteopathic Manipulative Treatment, Botanicals
Procedure · Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
12 Months to 60 Months
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2002
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 21, 2013 · Synced Sep 23, 2026, 3:06 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Quantitative Ultrasound Biomarkers to Assess Upper Trapezius Muscles in Patients With Chronic Pain

NCT05497622
View directory record Official record
Conditions
Chronic Neck Pain
Interventions
Quantitative Ultrasound, Osteopathic TART Assessment, Osteopathic Manipulation Treatment
Diagnostic Test · Procedure
Lead sponsor
Rocky Vista University, LLC
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Ivins, Utah
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Sep 23, 2026, 3:06 PM EDT
Completed Not applicable Interventional

Effect of Osteopathic Manipulative Medicine on Motor Function and Quality of Life in Cervical Dystonia

NCT02420106
View directory record Official record
Conditions
Cervical Dystonia
Interventions
Osteopathic Manipulative Medicine
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
2 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2019 · Synced Sep 23, 2026, 3:06 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Motion Capture and Analysis of NYIT Athletes

NCT02727049
View directory record Official record
Conditions
Athletic Injuries
Interventions
Osteopathic manipulative medicine (OMM)
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Oct 11, 2017 · Synced Sep 23, 2026, 3:06 PM EDT
Recruiting Not applicable Interventional

OPT-IN: Osteopathic Plagiocephaly Treatment for Infants and Neonates

NCT05848895
View directory record Official record
Conditions
Plagiocephaly, Nonsynostotic, Plagiocephaly, Positional, Plagiocephaly, Cranium; Deformity
Interventions
Osteopathic Manipulative Treatment, Standard of Care Repositioning
Procedure · Behavioral
Lead sponsor
Osteopathy's Promise to Children
Other
Eligibility
1 Day to 4 Months
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 2, 2025 · Synced Sep 23, 2026, 3:06 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Multiple Component Mobile-aid Pain Reduction Intervention to Decrease Myofascial Pain

NCT05860205
View directory record Official record
Conditions
Myofascial Pain Syndrome
Interventions
Multiple Component Mobile-Aid Pain Reduction Intervention, Osteopathic Manipulation Treatment, Sham Osteopathic Manipulation
Behavioral · Other
Lead sponsor
Kailea Manning
Other
Eligibility
18 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
2
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated May 15, 2023 · Synced Sep 23, 2026, 3:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutrient Nutritional Advise for Low Back Pain Patients Seeking Chiropractic Care

NCT04134013
View directory record Official record
Conditions
Low Back Pain, Nutrition Poor
Interventions
Combination: Nutrition AND Chiropractic Adjustment, Chiropractic Adjustment: Spinal Manipulation Therapy
Dietary Supplement · Other
Lead sponsor
Parker University
Other
Eligibility
21 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2022 · Synced Sep 23, 2026, 3:06 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Acute Low Back Pain in the Emergency Department Treated With Osteopathic Manipulative Treatment Versus NSAIDs

NCT04129437
View directory record Official record
Conditions
Low Back Pain
Interventions
Ibuprofen, Osteopathic manipulative treatment
Drug · Procedure
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 6, 2022 · Synced Sep 23, 2026, 3:06 PM EDT
Completed Not applicable Interventional

OMT & Intractable Singultus

NCT07149025
View directory record Official record
Conditions
Hiccup
Interventions
Osteopathic Manipulative Therapy
Procedure
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Sep 23, 2026, 3:06 PM EDT
Terminated Not applicable Interventional

Osteopathic Manipulative Treatment and Postural Control: Systems Engineering Approach

NCT02261233
View directory record Official record
Conditions
Low Back Pain
Interventions
Osteopathic manipulative treatment
Procedure
Lead sponsor
Michigan State University
Other
Eligibility
21 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
3
States / cities
East Lansing, Michigan • Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 3, 2019 · Synced Sep 23, 2026, 3:06 PM EDT
Not listed Not applicable Interventional

Comparison of Craniosacral Therapy vs Pelvic Floor Physical Therapy

NCT03213522
View directory record Official record
Conditions
Multiple Sclerosis, Bladder Dysfunction, Urinary Incontinence, Overactive Bladder
Interventions
Pelvic Floor Physical Therapy, Craniosacral Therapy
Procedure
Lead sponsor
CentraState Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Freehold, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 10, 2017 · Synced Sep 23, 2026, 3:06 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Osteopathic Manipulation Therapy in the Treatment of Interstitial Cystitis

NCT00873171
View directory record Official record
Conditions
Interstitial Cystitis
Interventions
Not listed
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 23, 2026, 3:06 PM EDT