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ClinicalTrials.gov public records Last synced Oct 3, 2026, 8:36 PM EDT

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Showing 49–72 of 144 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Osteopathic Manipulative Treatments Clear all
Recruiting Not applicable Interventional

Chronic Low Back Pain and Osteopathic Manipulation Treatment

NCT07161661
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP), Low Back Pain
Interventions
Usual VA Care, Osteopathic manipulative treatment
Procedure
Lead sponsor
Edward Hines Jr. VA Hospital
Federal
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 3, 2026, 8:36 PM EDT
Completed Phase 3 Interventional Results available

Osteopathic Health Outcomes in Chronic Low Back Pain (OSTEOPATHIC) Trial

NCT00315120
View directory record Official record
Conditions
Low Back Pain
Interventions
A. Active OMT and active UST, B. Sham OMT and active UST, C. Active OMT and sham UST, D. Sham OMT and sham UST
Procedure
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
21 Years to 69 Years
Enrollment
455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 6, 2016 · Synced Oct 3, 2026, 8:36 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

OMILQ: Osteopathic Manipulation to Increase Lactation Quantity (OMILQ)

NCT03875794
View directory record Official record
Conditions
Osteopathic Manipulation
Interventions
Osteopathic Manipulation
Other
Lead sponsor
AdventHealth
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2022 · Synced Oct 3, 2026, 8:36 PM EDT
Recruiting Not applicable Interventional

VCOM Pain Free Research Collaborative

NCT06533345
View directory record Official record
Conditions
Chronic Pain
Interventions
Behavior Change Coaching, Nutrition, Autonomic Recalibration, Dry Needling, Osteopathic Manipulative Treatment, Counseling Psychology, Multiple Treatments
Behavioral · Other · Procedure
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
21 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 3, 2026, 8:36 PM EDT
Completed Not applicable Interventional

OMT as an Adjunctive Treatment in MDD

NCT05065580
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
Corewell Health South
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Saint Joseph, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 3, 2026, 8:36 PM EDT
Withdrawn Not applicable Interventional

Osteopathic Manipulative Treatment for Recurrent Mastitis

NCT05132426
View directory record Official record
Conditions
Mastitis
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Western University of Health Sciences
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 3, 2026, 8:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Osteopathic Manipulative Treatment and Bio Electro-Magnetic Regulation Therapy on Low Back Pain in Adults.

NCT04704375
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
Bio Electro-Magnetic Regulation (BEMER) Therapy, OMT (osteopathic manipulative treatment), Light touch
Device · Procedure
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 3, 2026, 8:36 PM EDT
Completed No phase listed Observational

Cost Effectiveness of OMT for Chronic Low Back Pain

NCT03532230
View directory record Official record
Conditions
Lumbar Radiculopathy, Lesion of Sciatic Nerve, Left Lower Limb, Lesion of Sciatic Nerve, Right Lower Limb, Lumbar Spinal Stenosis, Lumbar Spondylosis, Lumbago With Sciatica, Left Side, Lumbago With Sciatica, Right Side
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 84 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
East Lansing, Michigan • Stratford, New Jersey • Voorhees Township, New Jersey
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Oct 3, 2026, 8:36 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Physical Exam, Static & Dynamic Ultrasound Assessment, & Treatment of Thoracolumbar Fascia (TLF) Mediated Low Back Pain

NCT06818175
View directory record Official record
Conditions
Low Back Pain, Chronic Low-back Pain, Acute Low Back Pain
Interventions
Ultrsound Guided Hydrodissection of the Thoracolumbar Fascia, Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 50 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 3, 2026, 8:36 PM EDT
Completed Not applicable Interventional

COMET-AOA: Median Nerve Stiffness in Mild-Moderate CTS With OMT & Conservative Therapy

NCT06150443
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Osteopathic manipulative treatment (OMT), Conservative treatment
Other
Lead sponsor
Kettering Health Network
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 3, 2026, 8:36 PM EDT
Terminated Not applicable Interventional

Osteopathic Manipulative Treatment and Postural Control: Systems Engineering Approach

NCT02261233
View directory record Official record
Conditions
Low Back Pain
Interventions
Osteopathic manipulative treatment
Procedure
Lead sponsor
Michigan State University
Other
Eligibility
21 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
3
States / cities
East Lansing, Michigan • Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 4, 2019 · Synced Oct 3, 2026, 8:36 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Motion Capture and Analysis of NYIT Athletes

NCT02727049
View directory record Official record
Conditions
Athletic Injuries
Interventions
Osteopathic manipulative medicine (OMM)
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Oct 3, 2026, 8:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Treatment and Its Relationship to Autonomic Nervous System Activity

NCT00516984
View directory record Official record
Conditions
Healthy
Interventions
Placebo, Sham, OMT
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
19 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 22, 2008 · Synced Oct 3, 2026, 8:36 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Lymphatic Osteopathic Manipulative Medicine to Enhance Coronavirus (COVID-19) Vaccination Efficacy

NCT05069636
View directory record Official record
Conditions
COVID-19
Interventions
Lymphatic OMM, Light Touch
Other
Lead sponsor
Rowan University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Stratford, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Oct 3, 2026, 8:36 PM EDT
Completed No phase listed Observational

OMM Utilization in the Clinical Setting

NCT02395965
View directory record Official record
Conditions
Conditions Treated With OMT
Interventions
Not listed
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
1,960 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
17
States / cities
Glendale, Arizona • Visalia, California • Durango, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2015 · Synced Oct 3, 2026, 8:36 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Techniques for the Treatment of Chronic Migraine Headaches

NCT04520425
View directory record Official record
Conditions
Chronic Migraine, Headache
Interventions
Osteopathic manipulative therapy
Procedure
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 3, 2026, 8:36 PM EDT
Recruiting Not applicable Interventional

OPT-IN: Osteopathic Plagiocephaly Treatment for Infants and Neonates

NCT05848895
View directory record Official record
Conditions
Plagiocephaly, Nonsynostotic, Plagiocephaly, Positional, Plagiocephaly, Cranium; Deformity
Interventions
Osteopathic Manipulative Treatment, Standard of Care Repositioning
Procedure · Behavioral
Lead sponsor
Osteopathy's Promise to Children
Other
Eligibility
1 Day to 4 Months
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 3, 2026, 8:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of OMT on Gait Kinematics and Postural Control in Parkinson Disease

NCT04946760
View directory record Official record
Conditions
Parkinson Disease
Interventions
Sham Manipulation
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
50 Years and older
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Oct 3, 2026, 8:36 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

The Effect of Osteopathic Manipulative Techniques on Human Tear Composition

NCT07633496
View directory record Official record
Conditions
No Disease or Condition is Being Directly Studied, The Focus of the Study in Healthy Volunteers
Interventions
Osteopathic Manipulative Treatment, Sham
Other
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Erie, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 3, 2026, 8:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Spencer's Technique on Shoulder Function

NCT06447493
View directory record Official record
Conditions
Shoulder
Interventions
Osteopathic Manipulative Treatment-Spencer's Technique (Modified), Rest
Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 3, 2026, 8:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preliminary Evaluation of an Osteopathic Manipulative Treatment (OMT) to Prevent Motion Sickness Symptoms

NCT05611814
View directory record Official record
Conditions
Motion Sickness
Interventions
Osteopathic Manipulative Treatment, Sham treatment
Other
Lead sponsor
United States Army Aeromedical Research Laboratory
Federal
Eligibility
19 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Fort Rucker, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 10, 2022 · Synced Oct 3, 2026, 8:36 PM EDT
Recruiting Not applicable Interventional

Impact of OMT on the Symptoms of Dysmenorrhea

NCT07849140
View directory record Official record
Conditions
Dysmenorrhea
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Western University of Health Sciences
Other
Eligibility
20 Years to 51 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 3, 2026, 8:36 PM EDT
Completed Not applicable Interventional

Changes in Pain, Spasticity, and Quality of Life After Use of Counterstrain Treatment in Individuals With SCI

NCT05559255
View directory record Official record
Conditions
Pain, Spasticity, Muscle, Quality of Life
Interventions
Counterstrain manual manipulative treatment
Other
Lead sponsor
William Carey University
Other
Eligibility
21 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Hattiesburg, Mississippi
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Oct 3, 2026, 8:36 PM EDT
Completed Not applicable Interventional

Ultrasound Evaluation of OMT for Sacral Base Asymmetry

NCT02820701
View directory record Official record
Conditions
Manipulation, Osteopathic
Interventions
OMT
Procedure
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
20 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Kirksville, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Oct 3, 2026, 8:36 PM EDT